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What Drug is the best serotonin receptor antagonist?

serotonin

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#1 kurdishfella

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Posted 17 January 2018 - 04:17 PM


Meds that block most serotonin receptors?

excluding: Cyproheptadine,Metergoline and Antipsychotic Meds.
Right now im looking at Mianserin and Mirtazapine.
Mianserin seems to be better. What do you guys think? Are there any other good serotonin antagonists?

 

 

 


Edited by farshad, 17 January 2018 - 04:17 PM.

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#2 jack black

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Posted 17 January 2018 - 05:17 PM

you best bet is tryptophan-free diet or blocking 5HT production (Fenclonine).

but, not sure if this is the right fix for "overactive" 5HT receptors.



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#3 kurdishfella

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Posted 18 January 2018 - 02:36 AM

you best bet is tryptophan-free diet or blocking 5HT production (Fenclonine).

but, not sure if this is the right fix for "overactive" 5HT receptors.

I know but  both are really difficult .... And I cant take fenclonine forever its toxic.

Diet I suppose works but I dont want 0 Serotonin...

 

Thats why I only thought serotonin receptor antagonists would work... I tried zyprexa once and it worked wonders but I Dont wanna block dopamine thats why im looking for a different serotonin receptor blocker..

 

Which serotonin receptors would be most involved in anxiety would you say?  So I can find a good med that targets them.

 

Mianserin seems promising right?

5-HT1A 400–2,600 
5-HT1B ≥2,800 
5-HT1D 220–400 
5-HT1E ND 
5-HT1F 13 
5-HT2A 1.6–55 
5-HT2B 1.6–20 
5-HT2C 0.63–6.5 
5-HT3 5.8–300 
5-HT4 ND ND 
5-HT5A ND ND 
5-HT6 55–81 
5-HT7 48–56


Edited by farshad, 18 January 2018 - 02:37 AM.


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#4 jaybird10 2

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Posted 18 January 2018 - 01:43 PM

mirtazapine helped my panic and anxiety a lot. So Id say try and block 5ht2c.







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