Hey Longecity, I made a topic about this before but I am still getting no where, just seen a Neurologist, i don't know where or what to try anymore, all the doctors have no idea..
Key parts:
WIRED (by this i mean I feel heavily stimulated), Going days without sleep or need for it, most I went was 10 days is confirmed at Northwick Park Hospital. When I am wired and getting sleep during this phase it is usually just a couple of hours, but typically not needed for days.
Recently this comes with a crash, where I finally get sleep, typically 24 - 30 hours and for usually 2/3 days in a row and feel shattered. I wake up shaking, with huge anxiety running in my veins, then without warning flips back to a wired stage. I never wake up feeling normal, the stimulation is always running.
When really Wired/Stimulated my speech races, can’t settle, I feel out of it, warm, headache, eyes feel heavy, pupils dilated (without mood changes, constantly depressed), can’t eat with the feeling in my stomach. I’ve physical symptoms when wired, such as my downstairs shrinking during ‘wired’ phase (constant but so much more dramatic it hurts to pee and I will know how bad it's going to get just by looking downstairs).
I am lately having a lot of fevers, sweating a lot but with low tempatures, dizziness and other symptoms not there at the start coming into play. (which I have a feeling is a consequence of 3 years living like this).
Doctors:
3 years i've had 60 general doctors appointments, 4 endocrinologists, cardiologist, MRI, CT, EEG, Psychiatrist for a year, and this week seen a Neurologist who had no suggestions, but said because my MRI and EEG are clear he doesn't see this as Neurological, even though to me it seems like the nervous system?
Medications tried:
Melatonin – No difference to sleep
Supplements – HTP5 etc for sleep – No difference
Zoloft – Added to WIRED effect (came off it within 2 weeks)
Mirtazapine – No change to Wired, happiest I’ve been in years, helped my depersonization, depression, anhedonia / emotions, only stopped it because I wanted to tackle this first, this is a medication I feel I need in the future.
Olanzapine – No difference but helped anxiety but not as much as I’d like, still would want to be on this in the future
Zopiclones – No difference and can’t make me sleep
Last year:
Lithium – No difference at 0.9 for months
Depokte – No difference at all for anything
Quietapine – Could make me sleep but not nightly, no change to Wired
Beta Blockers – Helps shakes (still on them)
Lamotrigine - (couldn’t tolerate)
Xanax & Clonazepam - Both can bring down the feeling a bit, even sometimes get me sleeping, but the sleep only lasts 4 hours and other symptoms are still apparent, including the wired just to a less degree and takes heavy amount. Also unlike a few years ago, I can’t feel even at large doses any drowsiness, relaxed or even positive feelings, my head is just numb, even with cigarettes, no positive feelings.
Symptoms in order they came in (all are still on going and worse):
Year before this wired feeling:
Depersonization/Anxiety/Derealisation/Depression/NO THOUGHTS/ BLANK MIND/No inner monolouge – This has really changed my life and after this wired thing is one of my biggest priorities. (I have been told this is deep depression/Anhedonia – Gets some better on Mirtazapine 4 months)
Fatigue
Bladder dysfunction – Physical shrinkage depending on how ‘wired’ I feel’
Dilated pupils – Eyes dilated very large, everyone points it out and feel heavy
Last two years:
Start of this “wired”, unable to get any sleep or switch of even though I am shattered – Feel stimulated 24/7
Excessive sweating
Physical Anxiety – Bad, especially with the shakes or when I go wired
Bad memory
Last year:
Crash – After days I crash, where I sleep for over 24 hours
Easily over-stimulated – Now can instantly go into ‘wired mode’ from a simple conversation and pupils will dilate and that can then stick for days
Tremors - I shake badly without beta-blockers and sometimes with (80mg)
Shortness of breath (don’t breath automatically anymore)
Exercise intolerance – Can’t walk a mile, when I was relatively fit before
Fevers - Every few weeks I’ll have a bad fever (but low temperature 33/34)
Intolerance to heat
Cognitive impairment – Dramatic
Craving SALT
High blood pressure – I’ve been told mildly high
Aching neck and shoulders – My neck is always tight
Muscle aches and/or joint pains – All day, expect when really wired
Excessive thirst - YES, drink 4 litters of water a day
Weight gain - Massive gain – from 12 stone to 16.5!
Restless leg syndrome Shaky Vision
Headache/migraine - ALL DAY EVERY DAY
Glazed eyes when wired, family notice it and can tell straight away
Last 6 months
Legs feel weak and shaky
A lot more fevers
Dizziness – Pretty constant
More wired than a year ago
Personality changes, more aggressive, agitated
Memory much worse
Generally feel weak
For me it's clear something is very wrong, when I have a drink, I can drink all night round the clock, some crazy amounts and it won't get me drowsy and i'll just be up the next day without being even hungover and i've been out twice in a row and still out drank and not needed any sleep, this thing makes noooo sense, i just want it to end...
Suggestions I’ve had, all of which the Neurologist said is not the case in his opinion:
Parasympathetic system is overactive
Dysautonomia
Adrenergic Storm
