Browser,
there are certain things I can and I can't say in the forum. Most things I can say revolve around micronized resveratrol, a form of resveratrol that was produced at 1.5 microns on the average. It is not marketing, when you are trying to describe what micronized resveratrol is, and what it does. Comparing Micronized resveratrol particle size, by seeing what Sirtris used is also not marketing. It is information for those that will come here at a later time, looking for answers as to what the heck is meant by "Micronized Resveratrol" whether it comes from one manufacturer or another.
You state that resveratrol lozenges that dissolve slowly are good, while I don't think anything that reduces the time of absorption is good for resveratrol. The point you are trying to make about rats, is pointless in my opinion because you as a human, can metabolize resveratrol very quickly while a rat does not. It is my belief at this time that significant plasma levels in humans cannot be reached with any slow dissolving, or timed release trans-resveratrol substance or product.
The point about resveratrol in ethanol, or micronized resveratrol is to increase absorption and see if a higher plasma levels are achieved immediately, to overcome the issue that your metabolism can quickly remove the 'trans-resveratrol' from your plasma. Because of this, regular resveratrol in a lozenge is not my first choice when it comes to Buccal absorption. Micronized resveratrol or ethanol dissolved resveratrol will certainly work much better for a Buccal application. Tablets and Lozenges are slow, and may have binders and the like, that may not help to produce fast absorption.
As you can see by checking the date I first posted this thread (09/27/2007), we were the first to dive into high absorption resveratrol, and we asked for opinions regarding micronizing resveratrol. We received a lot of feedback, and where the first to produce independently tested micronized resveratrol at 1.5 microns.
Diversity is good, but just because there is a new product on the market, certainly does not mean it is better than everything before it (or less expensive). Heck, we have even produced dry (no ethanol, just pure powder) nano-resveratrol that was measured at less than 50 nanometers by an independent lab. The fact that we can produce something like this which we believe to be the best, can't always be done in mass due to the expense of producing it (or packaging it without creating a large floating nano-resveratrol cloud).
We can create resveratrol gum, resveratrol lozenges, resveratrol drinks, nano-resveratrol powder, resveratrol eyedrops, resveratrol inhalers, resveratrol eardrops, resveratrol based anti-fungal cream, soluble dry resveratrol powder (for tang like) preparations... Oh YEaH! We certainly have the technology, know the people, and understand what it takes... however, what people like you want is not diversity. You simply want something that you believe works for your condition.
In my opinion, we already have the high absorption material people like you are looking for... but you think it is too expensive. It is funny that you believe that: Because a 20mg lozenge with sucralose (
http://www.holisticmed.com/splenda/) at $18.95 for 1.2 grams is really pretty high, when you can get 25 grams micronized resveratrol for $75. You have decided to basically pay $15.75 per gram of res in the lozenge, instead of $3 per gram of the pure micronized powder when buying bulk micronized powder.
I have to say, I definitely don't agree with the pricing of your lozenge product, specially because it does not use micronized resveratrol and because it dissolves slowly. Definitely not my personal choice, however if you are happy with it then keep on using it.
Cheers
A
Edited by Anthony_Loera, 20 April 2010 - 02:56 AM.