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Modafinil Trail


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#31 steelsky

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Posted 05 November 2008 - 08:40 AM

I'm not going to update daily from now on, but I will post anecdotes about the experience.

Update:

Slept about 7 hours yesterday (3+4), while stayed awake afterward for about 18 hours after that, where I felt sleepy only once during which, and near the end of the period. After that I've slept 7 hours (that's pretty low for my 9-10 standard). Woke up NATURALLY, but extremely sleepy ("motivation" was what made me get out of bed). After about an hour the sleepiness subsided and now I'm totally awake and alert. Note this strange fact: I DIDN'T take any dose since 2 days ago. Something in the Modafinil must have a long term effect outside the half-life period of the drug. Any thoughts about that?
I'm having a work related crisis for the past couple of days. I did feel stressed and depressed about it (as I usually do about these sort of things), but surprisingly I was able to "work past it", and might have eventually overcome it (my feeling about it, not the actually crisis), where usually I've always had kind of a problem with these sorts of things. So like reported - mood, while NOT higher, is much more manageable now. Interesting.

#32 steelsky

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Posted 06 November 2008 - 02:20 AM

I see no one comments on this thread anymore :(
Busy voting? :)

Update:

The effect of skipping a dose yesterday might have kicked in today. I've slept a lot. Not only that, taking a 50mg dose today didn't do much to my sleepiness. Even taking another 50mg afterward wasn't a hit. Had to force myself out of bed eventually.
I hope tomorrow I'll feel better from the self supposed "long term effect" of today's dose.

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#33 Wedrifid

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Posted 06 November 2008 - 04:42 AM

I see no one comments on this thread anymore :(
Busy voting? :)

Update:

The effect of skipping a dose yesterday might have kicked in today. I've slept a lot. Not only that, taking a 50mg dose today didn't do much to my sleepiness. Even taking another 50mg afterward wasn't a hit. Had to force myself out of bed eventually.
I hope tomorrow I'll feel better from the self supposed "long term effect" of today's dose.

Hi Steelsky. I'm still following along with interest. Your experiences with the 'long term effect' and also the need to have recovery days matched my own. I was far less rigorous in my recording so watching your reports is useful for me, paticularly as I plan getting my supply back.

Careful with too much yo-yoing about between manic energy and fatigue. The similarity to the symptoms of bipolar is not coincidental.

#34 Heliotrope

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Posted 06 November 2008 - 06:12 AM

I've tried adrafinil and a small sample of modafinil (Modalert). Modafinil was certainly faster-acting and seemed more potent to me. The effects are there, including the sulfur smell in my urine, stronger under modafinil, ~indetectable w/ adrafinil.

I believe I have Excessive sleepiness too, and suffer from work-shift disorder etc. Provigil is about the most expensive brand of modafinil out there, but if you insurance covers it, your Co-Pay may cost less. If you spend 4% of your income on modafinil, then it may not be worth the expensive habit. I'm a college student, and really used "parents' money", though I work and earn my own share of money too.


Cephalon has the 7-day Free trial, w/ 7 pills of 200mg Provigil, 1,400 mg total, a good starting amt to try the real deal. I'm lucky that I've never been majorly ill, and so I only know my current doctor's name (not even sure where the doctor's office is), and never even met him. He's the HMO type , under the network Blue-Cross Blue-Shields provided by my mom's employer. I know there's doc-patient confidentiality, but i wouldn't want parents finding out... me taking "life-style" pills.

When I'm independent in real-world on my own, I may shop around and find an agreeable doc who will ask little and just give me the prescription.

Edited by HYP86, 06 November 2008 - 06:19 AM.


#35 steelsky

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Posted 06 November 2008 - 02:47 PM

I'm glad you guys are staying tuned.

As far as today's update - taking the 50mg X2 doses did not work immediately. This means that contrary to when I first started with a couple of 50mg doses, I did not see a peak in alertness 2 hours after intake. I do however see an extreme improvement after the half-life period. Now, 15 hours after the last 50mg dose, I feel completely alert with no sleepiness whatsoever (not even the usual slight sleepiness common with me during the day). Another clue to Modafinil being the culprit to this is my low appetite (NO appetite, actually).

The main problem is that I wanted to be awake when I took the doses, not now (this interferes with my schedule). Oh well.

#36 steelsky

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Posted 07 November 2008 - 05:50 AM

Update:

Today I've taken 100mg and went back to sleep (to hopefully wake up invigorated), but even though I've set the alarm to an hour later, I woke up 7 hours later, still feeling sleepy. Good news is that they initial sleepiness faded after a while.
I hope this "set-back" is temporary.

#37 steelsky

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Posted 07 November 2008 - 06:38 PM

So far my sleepiness hasn't improved (meaning I still feel generally very sleepy throughout the day), but note that my "cognitive functions" (intentionally in apostrophes, as it is a general feeling and not something I've actually checked properly) is a bit higher than usual. The difference is not profound at all, but some features have been slightly improved, notably working memory and long term memory. The latter is more surprising as Modafinil is supposed to mainly affect the former. I've noticed that it's easy for me now to remember events from the past, quotes, names and faces.

Returning to the sleepiness - I think that I was wrong is assuming that taking Modafinil dose and going to sleep right after, like I've used to do with Ritalin, will make me wake up naturally, alert and ready.

#38 leaving_florida

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Posted 08 November 2008 - 01:06 AM

So far my sleepiness hasn't improved (meaning I still feel generally very sleepy throughout the day), but note that my "cognitive functions" (intentionally in apostrophes, as it is a general feeling and not something I've actually checked properly) is a bit higher than usual. The difference is not profound at all, but some features have been slightly improved, notably working memory and long term memory. The latter is more surprising as Modafinil is supposed to mainly affect the former. I've noticed that it's easy for me now to remember events from the past, quotes, names and faces.

Returning to the sleepiness - I think that I was wrong is assuming that taking Modafinil dose and going to sleep right after, like I've used to do with Ritalin, will make me wake up naturally, alert and ready.

OK, you brought up a previous interesting point. I've noticed many times that after I take moda early in the day, there's no much of a difference. But for some strange reason... 10-13 hours later... I seem to be more alert that I normally would be - much more alert. Any thougts? I'd love to know if there was a logical explanation for this.

#39 Heliotrope

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Posted 08 November 2008 - 10:04 AM

So far my sleepiness hasn't improved (meaning I still feel generally very sleepy throughout the day), but note that my "cognitive functions" (intentionally in apostrophes, as it is a general feeling and not something I've actually checked properly) is a bit higher than usual. The difference is not profound at all, but some features have been slightly improved, notably working memory and long term memory. The latter is more surprising as Modafinil is supposed to mainly affect the former. I've noticed that it's easy for me now to remember events from the past, quotes, names and faces.

Returning to the sleepiness - I think that I was wrong is assuming that taking Modafinil dose and going to sleep right after, like I've used to do with Ritalin, will make me wake up naturally, alert and ready.

OK, you brought up a previous interesting point. I've noticed many times that after I take moda early in the day, there's no much of a difference. But for some strange reason... 10-13 hours later... I seem to be more alert that I normally would be - much more alert. Any thougts? I'd love to know if there was a logical explanation for this.



i dunno. it could be analogous to the 2nd wind of distance running, sudden revival in the late period. i've finished marathons (26 miles) and ran half-marathon to near-marathon distance events. Let's take 1 mile as analgous to 1 hour.

i know, distance to time, doesn't compute, but just think some that 1 mile, 1 hr whatever as a base unit, and call it 1 unit.

I've noticed that when i take 1 unit early and immediately the response's not good (.5, 1, even 2 miles into the run), i'm tired, feel crappy, out of breath, and just plain feel like quitting the run right then.

BUT 10-13 units later (or 10-13 miles later), i could feel almost a weird esoteric happy, runner's high, heavenly, alert, feeling, purely effect of my body, no drugs (not even caffiene). feels better than i'd normally feel, and much more alert

Edited by HYP86, 08 November 2008 - 10:06 AM.


#40 Wedrifid

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Posted 08 November 2008 - 04:04 PM

So far my sleepiness hasn't improved (meaning I still feel generally very sleepy throughout the day), but note that my "cognitive functions" (intentionally in apostrophes, as it is a general feeling and not something I've actually checked properly) is a bit higher than usual. The difference is not profound at all, but some features have been slightly improved, notably working memory and long term memory. The latter is more surprising as Modafinil is supposed to mainly affect the former. I've noticed that it's easy for me now to remember events from the past, quotes, names and faces.

It's easier to remember things when you're actually alert enough to process them in the first place!

Returning to the sleepiness - I think that I was wrong is assuming that taking Modafinil dose and going to sleep right after, like I've used to do with Ritalin, will make me wake up naturally, alert and ready.

Interesting. What worked for me was a modafinil + caffeine combo then another 45 mins sleep. That was before I got a CPAP machine and discovered what sleep works like when you breath at the same time.

#41 steelsky

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Posted 09 November 2008 - 07:34 PM

So far my sleepiness hasn't improved (meaning I still feel generally very sleepy throughout the day), but note that my "cognitive functions" (intentionally in apostrophes, as it is a general feeling and not something I've actually checked properly) is a bit higher than usual. The difference is not profound at all, but some features have been slightly improved, notably working memory and long term memory. The latter is more surprising as Modafinil is supposed to mainly affect the former. I've noticed that it's easy for me now to remember events from the past, quotes, names and faces.

It's easier to remember things when you're actually alert enough to process them in the first place!


True, but I was referring to a speculation that it might have extended my limit, meaning that my memory functions are better than they even COULD be without the Modafinil. But evidence is circumstantial, so I can't know for sure.

Regarding Modafinil's "after effect" - indeed, I'm searching for a reasonable explanation. The only one I could find is that Modafinil might have an extended influence on the system which is beyond its effect when it is present in the body, much like common SSRIs. However, I'm not sure how that works. I don't think the drug changes anything in the brain structure or biochemistry, so I have no idea how it can affect the brain when it's not present.

#42 Wedrifid

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Posted 10 November 2008 - 05:07 AM

True, but I was referring to a speculation that it might have extended my limit, meaning that my memory functions are better than they even COULD be without the Modafinil. But evidence is circumstantial, so I can't know for sure.

This is the sort of thing I would like to be able to trace. I'm developing a system that does just that.

#43 Wedrifid

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Posted 10 November 2008 - 05:09 AM

Regarding Modafinil's "after effect" - indeed, I'm searching for a reasonable explanation. The only one I could find is that Modafinil might have an extended influence on the system which is beyond its effect when it is present in the body, much like common SSRIs. However, I'm not sure how that works. I don't think the drug changes anything in the brain structure or biochemistry, so I have no idea how it can affect the brain when it's not present.


Do you have a link for that or is it your own theory? I haven't been able to find anything that isn't anecdotal and yet I do not doubt my own experience, yours, or the other observations I have followed.

#44 steelsky

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Posted 10 November 2008 - 10:47 AM

Regarding Modafinil's "after effect" - indeed, I'm searching for a reasonable explanation. The only one I could find is that Modafinil might have an extended influence on the system which is beyond its effect when it is present in the body, much like common SSRIs. However, I'm not sure how that works. I don't think the drug changes anything in the brain structure or biochemistry, so I have no idea how it can affect the brain when it's not present.


Do you have a link for that or is it your own theory? I haven't been able to find anything that isn't anecdotal and yet I do not doubt my own experience, yours, or the other observations I have followed.


That's exactly my point - this is something I feel (this whole thread is so, admittedly), but I haven't found any publication supporting it.

#45 leaving_florida

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Posted 12 November 2008 - 05:38 PM

Regarding Modafinil's "after effect" - indeed, I'm searching for a reasonable explanation. The only one I could find is that Modafinil might have an extended influence on the system which is beyond its effect when it is present in the body, much like common SSRIs. However, I'm not sure how that works. I don't think the drug changes anything in the brain structure or biochemistry, so I have no idea how it can affect the brain when it's not present.


Do you have a link for that or is it your own theory? I haven't been able to find anything that isn't anecdotal and yet I do not doubt my own experience, yours, or the other observations I have followed.

Wedrifid... do you also feel a "kick" way beyond the expected time frame? It's so strange in my case. Usually, there's not much to notice during the day, but 10-13 hours later... I can easily get into this weird, comfort-zone, concentration state... hard to explain. But, I sure never expected to experience so few effects in the early stage and then prominent effects in a later stage.

Edited by leaving_florida, 12 November 2008 - 05:40 PM.


#46 steelsky

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Posted 13 November 2008 - 12:14 PM

Update:
I've went on a two days break from Modafinil, using only Ritalin. After that I've taken a 100mg dose. The effectiveness was just when I had first started using it. This leads to the conclusion that a resistance might have been built, which leads to two solutions: taking a higher dose when using Modafinil regularly, or having breaks such as taking it every other day (which might be the choice for now, as increasing the dose would make it very expensive for me).

#47 leaving_florida

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Posted 13 November 2008 - 04:56 PM

Update:
I've went on a two days break from Modafinil, using only Ritalin. After that I've taken a 100mg dose. The effectiveness was just when I had first started using it. This leads to the conclusion that a resistance might have been built, which leads to two solutions: taking a higher dose when using Modafinil regularly, or having breaks such as taking it every other day (which might be the choice for now, as increasing the dose would make it very expensive for me).

Any chance this is some sort of "Jedi Mind Trick"? For example... when you first take it, you're expecting 'something', so whatever effects are present are a bit over exaggerated. Then after a few days, the average dose obviously doesn't induce the same mental state because the previous experiences were 'mentally-driven', so any effects are now a bit under exaggerated...?

There's a wide range of conflicting reports online about building up a tolerance, but I've found most of them have an opposite opinion - they feel you can skip a few days and still 'feel it'.

#48 steelsky

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Posted 14 November 2008 - 06:02 PM

Update:
I've went on a two days break from Modafinil, using only Ritalin. After that I've taken a 100mg dose. The effectiveness was just when I had first started using it. This leads to the conclusion that a resistance might have been built, which leads to two solutions: taking a higher dose when using Modafinil regularly, or having breaks such as taking it every other day (which might be the choice for now, as increasing the dose would make it very expensive for me).

Any chance this is some sort of "Jedi Mind Trick"? For example... when you first take it, you're expecting 'something', so whatever effects are present are a bit over exaggerated. Then after a few days, the average dose obviously doesn't induce the same mental state because the previous experiences were 'mentally-driven', so any effects are now a bit under exaggerated...?

There's a wide range of conflicting reports online about building up a tolerance, but I've found most of them have an opposite opinion - they feel you can skip a few days and still 'feel it'.


Is THAT the Jedi Mind Trick? I've always wanted to know :)

Anyway - I concur. Most reports claim that consecutive use makes them lower dosage, and there are also reports about it being effective even after a 10-12 hours period. I'll keep trying different things and report.

#49 Wedrifid

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Posted 15 November 2008 - 09:07 AM

Any chance this is some sort of "Jedi Mind Trick"? For example... when you first take it, you're expecting 'something', so whatever effects are present are a bit over exaggerated. Then after a few days, the average dose obviously doesn't induce the same mental state because the previous experiences were 'mentally-driven', so any effects are now a bit under exaggerated...?


Placebo effect.

#50 Wedrifid

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Posted 15 November 2008 - 09:10 AM

Wedrifid... do you also feel a "kick" way beyond the expected time frame? It's so strange in my case. Usually, there's not much to notice during the day, but 10-13 hours later... I can easily get into this weird, comfort-zone, concentration state... hard to explain. But, I sure never expected to experience so few effects in the early stage and then prominent effects in a later stage.

I wouldn't say 'kick'. Almost the opposite of kick, somehow. The weird, comfort zone concentration state fits. Good in general but not so good when the brain should be sleepy, not concentrating. Mostly very weird.

#51 Heliotrope

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Posted 15 November 2008 - 09:26 AM

Wedrifid... do you also feel a "kick" way beyond the expected time frame? It's so strange in my case. Usually, there's not much to notice during the day, but 10-13 hours later... I can easily get into this weird, comfort-zone, concentration state... hard to explain. But, I sure never expected to experience so few effects in the early stage and then prominent effects in a later stage.

I wouldn't say 'kick'. Almost the opposite of kick, somehow. The weird, comfort zone concentration state fits. Good in general but not so good when the brain should be sleepy, not concentrating. Mostly very weird.



i've experienced similar things. see my post above, commenting on a theory of why it might exist, comparing it to endurance exercise endevours (like in the mid-late stage of marathon race). it's a nice state of existence, but not such a healthy side effect like you say, when you need sleep and rest. i worry such extent of "toxicity" might tax the brain too much.

#52 leaving_florida

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Posted 16 November 2008 - 07:50 AM

i've experienced similar things. see my post above, commenting on a theory of why it might exist, comparing it to endurance exercise endevours (like in the mid-late stage of marathon race). it's a nice state of existence, but not such a healthy side effect like you say, when you need sleep and rest. i worry such extent of "toxicity" might tax the brain too much.

I read your response. It actually reminded me of when I used to run; however, I wasn't running 20+ miles, only about 12. You are correct. That first 1-2 miles was always hardest, and then I would get into this strange 'trance'. In fact, I always thought of it as a type of meditation. Eventually, it becomes combined with 'runner's high', and it feels like a comfortable, quasi-out-of-body-experience or something.

Anyway, it's very interesting that many people notice this... let's call it... "After Hours" modafinil effect. Sometimes I question how safe modafinil is for long-term use. What grabbed my attention was the University of Arkansas doing a study on whether modafinil can help people who have tinnitus. As it turns out, I have tinnitus. What I have personally noticed is that modafinil makes my tinnitus at least 60% worse. Yet, it doesn't seem to affect my tinnitus until 10-13 hours after taking it. Then, my tinnitus gradually subsides to it's original state after 35-40 hours. One of the main culprits behind tinnitus is an excitatory neurotransmitter called glutamate. Here's a little brief on glutamate:

"Glutamate is well known to have neurotoxic properties when excessively released or incompletely recycled. This is known as excitotoxicity and leads to neuronal death of the auditory nerve. Excess glutamate opens the sodium channel in the neuron and causes it to fire. Sodium continues to flow into the neuron causing it to continue firing. This continuous firing of the neuron results in a rapid buildup of free radicals and inflammatory compounds. These compounds attack the mitochondria, the energy producing elements in the core of the neuron cell. The mitochondria become depleted and the neuron withers and dies."

Why is glutamate relevant here? Well, a study from 1999 showed that modafinil increased extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus in the brain of a rat (http://www.nature.co...l/1395268a.html). So, putting 2 and 2 together... I've concluded the following: A) I have tinnitus. B) Glutamate plays a significant role in my tinnitus. C) Modafinil affects the levels of glutamate my brain; thus, making my tinnitus worse. D) Prolonged use of modafinil could possibly make my tinnitus permanently worse. Interestingly enough, the University of Arkansas gave tinnitus sufferers modafinil to see if it would help them concentrate on their task and not be distracted by tinnitus. What am I getting at? Why in the HELL would they conduct a study to help people, and end up giving them something that could potentially make them worse??? So, I decided to contact the university's department that conducted the study. After a few days, they responded and told me "nobody complained about it getting worse."

So, my point is... I'm not a conspiracy theorist, but I am a little weary of 'modafinil'. Hell, every year we find out stuff that we previously thought was good turns out to be bad for us, and vice versa. Therefore, when you say that you "worry about toxicity", I think that's a concern that should be taken seriously. But in all fairness, endless studys have shown modafinil to be very safe and well tolerated. Who knows?

#53 December15

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Posted 16 November 2008 - 08:28 PM

With all due respect, steelsky, I don't feel you have any right to "dismiss" valid experience derived reports regarding Prozac. Unfortunately that means I don't have the right as I would like to dismiss the rest of your Prozac hypothesis as fuzzy logic at best. I took Prozac for several years and it most definitely had a numbing effect on my emotional responses. It had nothing to do with simply "needing to learn to look at things in a different like"; I felt nothing no matter what happened in my life. That was the point at which when I realized something was awry and I began learning about Prozac and SSRIs. My dog could have been run over by a car in front of me and I would have felt - nothing. Various and sundry things took place in my life ranging from pretty good to pretty dismal and I felt - nothing. It was as though emotion was reduced to a ghost and even the ghost was fading away.

Back to Modafinil - I'm going to start a new thread, I don't want this particular post to get lost in a current thread.

December


Leaving_florida - I disagree, and actually dismiss the claims about Prozac making anyone "apathetic". I have not found this with my own experience but my theory expends further than that. I think that people taking Prozac need to adjust to a different mental state than they used to be in. I don't think it makes emotions more dull or hard to come by. I think that people were used to feel certain things about certain things, and now they have the ability to feel otherwise, but they assume they don't feel anything at all. To try mathematics - without Prozac one would feel -1 about a situation, yet Prozac brings him to feeling 0 about it. This means that the person needs to "work" in order to get to +1, as Prozac doesn't automatically make you happy, it just enables it. So even -1 is considered an emotion but 0 isn't, so people deduce that Prozac makes them apathetic, but that is because they need to start looking at things in a different like, or start "working" on feeling good about stuff.



#54 steelsky

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Posted 18 November 2008 - 08:19 AM

With all due respect, steelsky, I don't feel you have any right to "dismiss" valid experience derived reports regarding Prozac. Unfortunately that means I don't have the right as I would like to dismiss the rest of your Prozac hypothesis as fuzzy logic at best. I took Prozac for several years and it most definitely had a numbing effect on my emotional responses. It had nothing to do with simply "needing to learn to look at things in a different like"; I felt nothing no matter what happened in my life. That was the point at which when I realized something was awry and I began learning about Prozac and SSRIs. My dog could have been run over by a car in front of me and I would have felt - nothing. Various and sundry things took place in my life ranging from pretty good to pretty dismal and I felt - nothing. It was as though emotion was reduced to a ghost and even the ghost was fading away.

Back to Modafinil - I'm going to start a new thread, I don't want this particular post to get lost in a current thread.

December


Leaving_florida - I disagree, and actually dismiss the claims about Prozac making anyone "apathetic". I have not found this with my own experience but my theory expends further than that. I think that people taking Prozac need to adjust to a different mental state than they used to be in. I don't think it makes emotions more dull or hard to come by. I think that people were used to feel certain things about certain things, and now they have the ability to feel otherwise, but they assume they don't feel anything at all. To try mathematics - without Prozac one would feel -1 about a situation, yet Prozac brings him to feeling 0 about it. This means that the person needs to "work" in order to get to +1, as Prozac doesn't automatically make you happy, it just enables it. So even -1 is considered an emotion but 0 isn't, so people deduce that Prozac makes them apathetic, but that is because they need to start looking at things in a different like, or start "working" on feeling good about stuff.


December. I didn't dismiss valid experiences. I just proposed my theory. Notice the multiple "I think" references, meaning that being my own opinion on the matter. Sorry about your dog :)

Back to Modafinil - My update is that I've taken a break from it for 3 days, going back to using Ritalin when necessary. Today I've taken 100mg of Modafinil after not sleeping much. Its effect was minor at best. Noticeable, yet nothing compared to Ritalin's (which I had to take because the Modafinil didn't do much).
Possibly, taking 100mg was too much after such a break, rendering it less effective. Today I'm going to take 50mg dose, to see where it gets me.

Edited by steelsky, 18 November 2008 - 08:21 AM.


#55 leaving_florida

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Posted 18 November 2008 - 09:58 PM

December. I didn't dismiss valid experiences. I just proposed my theory. Notice the multiple "I think" references, meaning that being my own opinion on the matter. Sorry about your dog :)

Back to Modafinil - My update is that I've taken a break from it for 3 days, going back to using Ritalin when necessary. Today I've taken 100mg of Modafinil after not sleeping much. Its effect was minor at best. Noticeable, yet nothing compared to Ritalin's (which I had to take because the Modafinil didn't do much).
Possibly, taking 100mg was too much after such a break, rendering it less effective. Today I'm going to take 50mg dose, to see where it gets me.

I think you should stop playing games. 50mgs? What do you hope to achieve with that? Honestly, you should take the 50mgs and flush it straight down the toilet because you'd get the same effect. Why don't you get brave and go for 300mgs? I'm not brave enough, so I want someone else to do it. :)

In all seriousness, how much Ritalin do you usually take in one dose?

#56 Wedrifid

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Posted 19 November 2008 - 03:57 AM

Why don't you get brave and go for 300mgs? I'm not brave enough, so I want someone else to do it. :)


300mg isn't as silly as it sounds. A narcoplectic would still laugh at you for taking less than 400mg.

I've tried 300mg. I wasn't nearly as wired as when I take 30mg of ritalin.

#57 Wedrifid

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Posted 19 November 2008 - 04:00 AM

Back to Modafinil - My update is that I've taken a break from it for 3 days, going back to using Ritalin when necessary. Today I've taken 100mg of Modafinil after not sleeping much. Its effect was minor at best. Noticeable, yet nothing compared to Ritalin's (which I had to take because the Modafinil didn't do much).
Possibly, taking 100mg was too much after such a break, rendering it less effective. Today I'm going to take 50mg dose, to see where it gets me.


100mg is an extremely low dose. If I were to compare it to a ritalin dose I'd weigh it as equivalent in stimulation to about 8mg of ritalin. To counter tiredness I would go up to 300mg of modafinil before I bothered adding in the ritalin.

#58 steelsky

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Posted 19 November 2008 - 05:53 AM

Back to Modafinil - My update is that I've taken a break from it for 3 days, going back to using Ritalin when necessary. Today I've taken 100mg of Modafinil after not sleeping much. Its effect was minor at best. Noticeable, yet nothing compared to Ritalin's (which I had to take because the Modafinil didn't do much).
Possibly, taking 100mg was too much after such a break, rendering it less effective. Today I'm going to take 50mg dose, to see where it gets me.


100mg is an extremely low dose. If I were to compare it to a ritalin dose I'd weigh it as equivalent in stimulation to about 8mg of ritalin. To counter tiredness I would go up to 300mg of modafinil before I bothered adding in the ritalin.


I accept your challenge. I will try 100mgX2 tomorrow. If I feel there's an improvement from 100mg but not enough - I'll try 300mg tomorrow. It's not a matter of being brave, it's a matter of being rich. As I've stated - Modafinil costs a fortune here. I will never be able to allow myself 300-500mg. Even 100 is a stretch. But it'd be good to know that it works, at least, for when I'll be able to get generic (or for when I'm finally rich).

Wedrifid - where did you get the translation ratio of 100 Mod = 8 Ritalin?

Yesterday I've taken 50mg Modafinil + 15mg Ritalin. It kept me "un-sleepy" for just less than 4 hours. Just now (2 hours after that) I'd taken another 50mg Modafinil + 20mg Ritalin. I'll update on how long it lasts.

About Ritalin, usually I take 20mg effective dose (either 20mg every 3-4 hours, or 40mg LA every 6-8).
Regarding the nootropic effect of the Modafinil - yesterday (when I went back on it), I was really concentrated on my work without even thinking about being concentrated. I wonder what I'll be able to do with 200mg Modafinil, or even higher.

Edited by steelsky, 19 November 2008 - 05:55 AM.


#59 Wedrifid

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Posted 19 November 2008 - 05:00 PM

I accept your challenge. I will try 100mgX2 tomorrow. If I feel there's an improvement from 100mg but not enough - I'll try 300mg tomorrow. It's not a matter of being brave, it's a matter of being rich. As I've stated - Modafinil costs a fortune here. I will never be able to allow myself 300-500mg. Even 100 is a stretch. But it'd be good to know that it works, at least, for when I'll be able to get generic (or for when I'm finally rich).

Woah! I am all in favour of a minimalist approach! By all means go ahead with 300mg when you need it, but let it be clear: I advocate 100mg once or twice a day plus a good night's sleep!

:)

Wedrifid - where did you get the translation ratio of 100 Mod = 8 Ritalin?

My arse. Apart from reference to standard dosing protocols it is completely subjective and even comparing the two is probably meaningless.

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#60 steelsky

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Posted 20 November 2008 - 10:33 AM

OK, I was able to order Modafinil from two places online (airsealed and nubrain, the former have already sent the item), and if they wont get busted in customs - this makes what I currently pay for 100mg a day to be for ~250mg. When it arrives I will try 200mg. Today, however, I've only taken 50mg + 5mg of Ritalin, which was about enough for 3 hours. Later I took another 50mg of Modafinil + 10mg Ritalin and went to sleep, after which I've woken up naturally 2 hours later very alert. Even later I took 20mg Ritalin. The whole deal is 100mg Modafinil + 35mg Ritalin. This lasted me a whole day with 8 hours of sleep. I went to sleep three times (prior to two of which I've taken doses) and was able to be very productive (while awake, of course... not during sleep). This seems to work well, and more balanced than taking 60-80mg of Ritalin (throughout the day) which gave me stimulating "rushes".
Goal for when the Modafinil package arrives is to use 100mgX1 Modafinil without Ritalin. Will update soon.




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