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Does cigarette smoking protect against COVID-19?

tobacco cigarette smoking coronavirus covid-19

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#1 Lady4T

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Posted 11 May 2020 - 06:55 AM


Today I came across this study paper:

 

COVID-19 and smoking: A systematic review of the evidence

 

http://www.tobaccoin...119324,0,2.html

 

Excerpts from results of five different studies:

 

"Among the 191 patients, there were 54 deaths, while 137 survived. Among those that died, 9% were current smokers compared to 4% among those that survived, . . ."

 

"Similarly, Zhang et al.10 presented clinical characteristics of 140 patients with COVID-19. The results showed that among severe patients (n=58), 3.4% were current smokers and 6.9% were former smokers, in contrast to non-severe patients (n=82) among which 0% were current smokers and 3.7% were former smokers, . . ."

 

"In this study, none of those who needed to be admitted to an ICU (n=13) was a current smoker."

 

"Among the patients with severe symptoms, 16.9% were current smokers and 5.2% were former smokers, in contrast to patients with non-severe symptoms where 11.8% were current smokers and 1.3% were former smokers. Additionally, in the group of patients that either needed mechanical ventilation, admission to an ICU or died, 25.5% were current smokers and 7.6% were former smokers."

 

". . . among their population of 78 patients with COVID-19 that the adverse outcome group had a significantly higher proportion of patients with a history of smoking (27.3%) than the group that showed improvement or stabilization (3.0%), . . ."

 

 

Interesting, isn't it?  Hmmm...

 


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#2 Lady4T

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Posted 11 May 2020 - 08:30 AM

I did some more digging, and found this other one, that even has U.S. data

 

Smoking, vaping and hospitalization for COVID-19

https://www.qeios.com/read/Z69O8A.13

 

Excerpt:

 

"The prevalence of current smoking ranged from 1.4% to 12.6%. The random effect pooled prevalence of current smoking was 6.5% (95%CI: 4.9-8.2%). This preliminary analysis does not support the argument that current smoking is a risk factor for hospitalization for COVID-19. Instead, these consistent observations, which are further emphasized by the low prevalence of current smoking among COVID-19 patients in the US (1.3%), raises the hypothesis that nicotine may have beneficial effects on COVID-19." 

 

 


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#3 Lady4T

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Posted 11 May 2020 - 12:20 PM

Another one:

The Characteristics of 50 Hospitalized COVID-19 Patients With and Without ARDS

https://www.aerztebl.../article/213455

 

If you look at Table 1 "Patient Characteristics," it shows that out of the 50 patients, only 3 were smokers and none of them developed ARDS.

 

 


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#4 Ames

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Posted 31 July 2021 - 03:40 PM

COVID (and spike protein exposure) leads to large pools of S1 presenting non classical monocytes, out to 15 months post infection (long-lived monocytes harboring spike protein).

 

You will have these pools from being exposed to COVID, even if you remain sub-clinical, if you get vaxed, and maybe if you are exposed to vaxed people.

 

In general, you will have an elevated pool of non classical monocytes if you have any number of other diseases as well, to include obesity. Possibly explaining one reason why obese people succumb to COVID at a greater rate.

 

The trick may be keeping these pools low.

 

Nicotine induces monocyte death. Probably can be synthetic (ie: divorced from smoking tobacco - like a lozenge or gum). 

 

https://www.biorxiv.....06.25.449905v1

 

https://www.healthri...ked-long-covid/

 

https://pubmed.ncbi....h.gov/20601189/

 

https://pubmed.ncbi....h.gov/11179076/

 

https://mssociety.ca...ms-like-disease

 

 


Edited by Ames, 31 July 2021 - 03:49 PM.

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#5 Lady4T

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Posted 08 September 2021 - 11:46 PM

Super interesting!

Thank you for the good info and the great links.  Off to do some reading.

 

COVID (and spike protein exposure) leads to large pools of S1 presenting non classical monocytes, out to 15 months post infection (long-lived monocytes harboring spike protein).

 

You will have these pools from being exposed to COVID, even if you remain sub-clinical, if you get vaxed, and maybe if you are exposed to vaxed people.

 

In general, you will have an elevated pool of non classical monocytes if you have any number of other diseases as well, to include obesity. Possibly explaining one reason why obese people succumb to COVID at a greater rate.

 

The trick may be keeping these pools low.

 

Nicotine induces monocyte death. Probably can be synthetic (ie: divorced from smoking tobacco - like a lozenge or gum). 

 

https://www.biorxiv.....06.25.449905v1

 

https://www.healthri...ked-long-covid/

 

https://pubmed.ncbi....h.gov/20601189/

 

https://pubmed.ncbi....h.gov/11179076/

 

https://mssociety.ca...ms-like-disease

 


Edited by Lady4T, 09 September 2021 - 12:00 AM.

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#6 joelcairo

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Posted 29 September 2021 - 07:24 PM

I didn't read these articles in minute detail, but there does not appear to be a counterintuitive benefit from smoking:

 

Are smokers protected against SARS-CoV-2 infection (COVID-19)? The origins of the myth

https://www.nature.c...533-021-00223-1

 

Smokers up to 80% more likely to be admitted to hospital with Covid, study says

https://www.theguard...-study-suggests

 

 


Edited by joelcairo, 29 September 2021 - 07:25 PM.

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#7 Lady4T

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Posted 03 October 2021 - 05:15 AM

Well, I just came across this:

 

A new report about Covid-19 just out a couple of days ago from the Department of Defense JAIC Project Salus

 

 

Among the many slides with graphs representing data collected, there's this one:

 

"Risk Model for Breakthrough Hospitalization"

 

 

The category "Smokers" is nowhere to be found in these highest risk categories. 

I highly doubt that they forgot to collect those numbers, since according to the MSM and some so-called "experts" have always been saying that smokers would be the group most at risk. Not to mention that it would just make sense to ascertain the prevalence of smoking in a respiratory/lung illness. My guess is that the data was indeed collected, and the category "Smokers" is somewhere way down near the bottom of the list.

 

Edit:  I tried to post the image, but obviously I have no clue how.

 


Edited by Lady4T, 03 October 2021 - 05:27 AM.

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