Could resveratrol be combined with megadoses of antioxidants like vitamin C and betacarotenes or would that counteract the beneficial effects?
As far as I know there's no conflict. I just thought there would be a conflict with chemo, but maybe I'm wrong.
I think Maxwatt might be able to answer these questions.
Some doctors feel resveratrol will interfere with the chemotherapy, but the explanation I received from a leukemia patient who'd discussed it with his doctor, is that this is because resveratrol is an antioxidant. This doesn't make sense to me, resveratrol is a poor antioxidant. The fact is, without studies, no one knows. But if you google [resveratrol chemotherapy] there are a lot of claims and trials for resveratrol as an adjuvant to chemo-therapy.
My friend with leukemia elected to follow the doctors orders. He had a fairly good prognosis of several years with treatment, did not want to potentially mess it up with resveratrol. But small-cell lung cancer is a death sentence; chemotherapy only draws it out a few months. If I had lung cancer I would be taking as much resveratrol as I could tolerate, at least five, up to 10 grams a day. Diarrhea is a problem for some people. I found that taking one dose mid-afternoon eliminated this for me, as did taking a sugar-salt drink on an empty stomach -- 1 cup water, 2 tsp sugar, 1/4 tp salt, do not eat or drink for an hour before or an hour after drinking.
Some googled articles that make resveratrol look like a promising adjuvant to at least some forms of chemotherapy:
Resveratrol, Grape Compound, Turns a Switch in Cancer Cells The grape compound trans-resveratrol turns a switch in cancer cells and may overcome chemotherapy resistance, North Carolona researchers claim.
www.psa-rising.com/medicalpike/resveratrol-july00.htm -
Curcumin or resveratrol added to conventional chemotherapy ... Apr 14, 2008 ... Researchers from the Barbara Ann Karmanos Cancer Institute in Detroit presented findings showing that adding curcumin or resveratrol to ...
www.news-medical.net/?id=37309 - 45k -
Analysis of resveratrol as a lung cancer chemopreventive agent in ... Resveratrol inhibits PAH bioactivation through reduced expression of the CYP 1A1 and ... Stilbene derivatives ; Phytoalexin ; Resveratrol ; Chemotherapy ; ...
cat.inist.fr/?aModele=afficheN&cpsidt=16195807
Karmanos Researchers Find Non-Toxic Agents Added to Conventional ... Karmanos researchers investigated whether the addition of non-toxic substances curcumin and resveratrol to chemotherapy (FOLFOX) would decrease the survival ...
www.reuters.com/article/pressRelease/idUS58156+13-Apr-2008+PRN20080413 -
Non-Toxic Agents Added To Conventional Chemotherapy Decrease ... Apr 14, 2008 ... Adding curcumin or resveratrol to conventional chemotherapy could be effective in preventing the growth of chemo-resistant colon cancer ...
www.emaxhealth.com/100/21660.html
ScienceDirect - American Journal of Obstetrics and Gynecology ... Use of Resveratrol to improve the effectiveness of cisplatin and .... with regard to the cooperative role of resveratrol with cytotoxic chemotherapy. ...
linkinghub.elsevier.com/retrieve/pii/S0002937805025615
Resveratrol Helps Kill Pancreatic Cancer Cells | Best Syndication The resveratrol also lowered the function of proteins in the cancer cell membranes making them more sensitive to chemotherapy. The cancer cells had trouble ...
www.bestsyndication.com/?q=20080325_resveratrol_pancreatic_cancer.htm