Pram usauge does not develop a tolerance (unlike piracetam)[1]. The other possible benefit would be enhanced high affinity choline uptake (unlike piracetam) [2].
[1] Poschel BP, Ho PM, Ninteman FW. Experientia. 1985 Nov 15;41(11):1433-5.
[2] Pavlik A, Benesova O, Dlohozkova N.
Act Nerv Super (Praha). 1987 Mar;29(1):62-5.
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