You should try this.
OCD is linked to low serotonin. Fatigue, blunted affect is depression, also low serotonin.
While the low serotonin theory has been debunked, serotoinergic substances would have a big impact on those symptoms.
I'd suggest this algorithm
http://psychotropica...al-ad-algorithm
It's definitely not low serotonin. I have high serotonin, I am very sensitive to serotonin increasing drugs and I have most of the personality traits strongly associated with increased serotonergic activity.
One disease model for autism is increased serotonin and this explains many of the symptoms of the disease as well as the personality traits associated with autism.
I don't understand the point of taking an SSRI when serotonin levels in the blood are presumably already too high and the patient shows signs of increased serotonergic activity. Do we really need to bash someone's skull with a hammer to solve a migraine?
We need a serotonin reuptake enhancer...
I have noticed something interesting. Reduced nmda activity can cause hypersensitivity of the 5ht2a receptor and possibly explain in part hallucinations from nmda antagonists. On the other hand, things like theanine which acts on glutamate receptors and indirectly gaba by being converted to gaba like glutamate itself is, can sometimes reduce and sometimes potentiate 5ht2a hyperactivity, but trends towards reducing. Also, Acetyl-cysteine practically every single time I take it worsen the serotonin issues I have. I am also sensitive to glutamate, gelatin or gummy bears which contain the glutamate amino acid, or l-glutamine as a supplement, tends to send me into extreme rage like seen in autism.
My thinking is obviously that as glutamate affects dopamine it also affects serotonin, so my sensitivity to serotonin may lie in part in my sensitivity to glutamate. This is after all one of the disease models for autism if I remember correctly.
But my experimentation with magnesium and creatine has not gone too well and I am at a loss.
Btw I will read your link and comment on it later. There is a lot to read.
Edited by PeaceAndProsperity, 14 March 2017 - 01:11 PM.