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Marine Pharmacology in 2012–2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Anti

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#1 Ruth

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Posted 03 July 2018 - 06:20 AM


http://www.mdpi.com/...97/15/9/273/htm The purpose of the current marine pharmacology review was to continue the marine preclinical pharmacology pipeline review series that was initiated in 1998 [1,2,3,4,5,6,7,8] by consolidating preclinical marine pharmacological research published during 2012–2013 in the global literature. The large number of peer-reviewed publications we have reviewed demonstrates that the global research effort involved chemists and pharmacologists from 43 countries, namely, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, China, Colombia, Egypt, Fiji, France, French Polynesia, Germany, Greece, India, Indonesia, Ireland, Israel, Italy, Japan, Malaysia, Mexico, Morocco, the Netherlands, New Zealand, Norway, Pakistan, Panama, Papua New Guinea, Russian Federation, Saudi Arabia, Slovenia, South Africa, South Korea, Spain, Sri Lanka, Switzerland, Taiwan, Thailand, United Kingdom, Vietnam, and the United States. Thus, during 2012–2013 the marine preclinical pharmaceutical pipeline continued to provide novel pharmacological lead compounds that enriched the marine clinical pharmaceutical pipeline. Currently, the clinical pharmaceutical pipeline consists of 6 pharmaceuticals approved by the U.S. Food and Drug Administration, and 29 compounds in Phase I, II and III of clinical pharmaceutical development, as shown at a dedicated website: http://marinepharmac...inPipeline.htm.

#2 Ruth

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Posted 03 July 2018 - 06:23 AM

http://www.scielo.br...ipt=sci_arttext Omega-3 fish oil supplements are widely consumed as source of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, presenting beneficial effects on human health. This study aimed to evaluate fifteen brands of omega-3 fish oil supplements available in Brazilian market in order to estimate the Brazilian reality regarding those supplements. Twelve fatty acids were quantified by gas chromatography with a flame ionization detector (GC-FID), and lipid profile were obtained via mass spectrometry fingerprinting using direct electrospray ionization mass spectrometry (ESI-MS) to assess the form in which fatty acids are present as well as the possible fraud existence. Among all analyzed samples, thirteen brands were revealed as EPA and DHA sources (90.2-440.3 and 77.8-302.3 mg g-1lipid, respectively) in triacylglycerols (TAG) or ethyl esters (EE) form. However, two brands were discovered with addition of large amounts of soybean oil, leading the final consumer to ingest this low-cost oil believing that they are consuming adequate doses of EPA and DHA.

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#3 Ruth

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Posted 03 July 2018 - 06:25 AM

https://www.scienced...128012994000013 Man is a masterpiece and is intimately linked to the environment from an evolutionary standpoint. The equation phenotype = genotype + environment that many of us learned at high school is just as relevant today, particularly in industrialized and polluted areas around the globe.





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