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Antidepressant-like effects of Δ9-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depres

cb1 cbd rimonanbant

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#1 Ruth

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Posted 06 July 2018 - 08:17 PM

"... Similarly, CB 1 receptors are also coupled to ERK cascades and the proneurogenic action of cannabinoids seems to be related to facilitation of ERK signaling [91, 122, 123]. Also, brain derived neurotrophic factor (BDNF), a neurotrophin that is found reduced in depressed patients, and that is up regulated after AD or cannabinoids treatment could be involved [121,124125126127. This neurotrophic factor has been implicated in adult hippocampal neurogenesis [128]. ..."
...Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?


Cannabinoids are pro-neurogenic neuroprotective-antioxidants.

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