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Dopamine disfunction

#dopamine #dopaminereceptor #d2dopamine

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6 replies to this topic

#1 Yojimbo94

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Posted 24 September 2018 - 11:23 PM


hi, I was addicted to the internet, video games, porn up to 22 years, my dopamine receptors were completely sold out, now I'm 300 days of nofap and noporn and I completely eliminated video games and heavily restricted the use of internet now after 1 year I'm soo much better, I passed ADHD, I have much more self-esteem, I can talk with girls and are more socially active, I no longer have depression and less social anxiety, but this to the point of abstinence from total internet, it takes 10-15 minutes (the time to write this post) to get me back all the symptoms of low dopamine and fall into a cycle of depression, it seems that my dopamine runs out too quickly, I can not afford to texting with girls that my social skills fall dramatically and returns anxiety, insecurity and low motivation, I wanted to know what I can do to solve this disabling dopamine problem.Is there anyone I can contact?

#2 mono

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Posted 04 October 2018 - 01:02 AM

I would try any of the racetam family if you haven’t already, for example Noopept as well. You might try phenylpiracetam in particular as it has a specific effect on dopamine transmission. But any of those racetams/nootropics in that family should help. There are herbs you could try like Rhodeola rosea or ashwagahnda too.

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#3 Yojimbo94

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Posted 04 October 2018 - 04:52 PM

use these nootropics does not desensitize the dopamine receptor and once the use is interrupted worse? they could only be a short-term solution, while I would like to get along well without using stimulants

#4 John250

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Posted 04 October 2018 - 08:16 PM

Look into Bromantane and 9-me-bc.

#5 mono

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Posted 05 October 2018 - 02:55 AM

use these nootropics does not desensitize the dopamine receptor and once the use is interrupted worse? they could only be a short-term solution, while I would like to get along well without using stimulants


Well use of these nootropics allows for more permanent changes in the brain, even once usage is interrupted. This can include changes in dopaminergic function too.

Edited by mono, 05 October 2018 - 02:57 AM.


#6 Yojimbo94

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Posted 05 October 2018 - 07:04 PM

so, does the use of racetam cause permanent brain changes at a permanent dopaminergic level even after you stop taking? are these improvements in dopamine transmission? are the receptors involved too?

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#7 mono

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Posted 05 October 2018 - 07:30 PM

Well I remember reading that some of the positive changes that took place in the brain from racetam use remained even when use was discontinued. I can say from experience that I agree with this. Studies on this are of course in brains that are already damaged, or rats, so may not be entirely relevant. But it was my understanding that something like phenylpiracetam that upregulated d2 receptor would leave a permanent/long term impact on the brain after extended use. Feel free to correct me if I am wrong.
Phenylpiracetam and Sulbutiamine are both known to induce dopamine receptor upregulation.

Edited by mono, 05 October 2018 - 07:42 PM.





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