Thanks. After two days I decided to stop Wellbutrin. I didn’t notice anything positive from it and I actually felt like it made amp weaker. I Research some more and found this is common as both drugs can compete with DAT therefore making amphetamine positives less effective. Plus my end goal is to be off all medication so I don’t want to start something new and then have to rely on that and go through withdrawl from that as well. What I am doing now to help reduce tolerance is the following. My typical day is 20mg amphetamine from Vyvanse in the morning and 20mg Adderall at noon and 20mg at 3pm. Yesterday I skipped my last dose of Adderall and took 50mg Bromantane instead with 150mg UMP. That night I took 810mg jiaogulan and 1200mg inositol and 750mg tyrosine. This morning with my Vyvanse I took 15mg 9-me-bc with 100mg caffeine, 300mg UMP, b12, 2g fish oil, 3g Taurine and 2mg nicotine. This let my Vyvanse last longer as the 9-me-bc is a MAOI. I’ll take my 20mg Adderall at 1pm and I’ll skip the 3pm dose and use 50-100mg Bromantane with some UMP instead. I’m tired but my 3pm dose I can handle skipping for now. I’ll try this for a week. Then once per week I’ll take 100mg phenylpiracetam at 3pm to upregulate d2 but only once per week as continuous use can downregulate D2. Then I’ll probably gradually reduce the 1pm Adderall dose until it’s gone. Then I’ll stay on 50mg Vyvanse(20mg amphetamine) with the above morning cocktail and gradually decrease the Vyvanse by 10mg per month. I hope this works.
I also decided to sell my nutrition store. When I sit here all day with nothing to do that is when I have my drug seeking behavior. I’m indoors with dim lighting and it’s not productive at all especially for someone with ADHD like myself. A few years ago I was able to completely get off amphetamines with a 10mg reduction of Vyvanse per month. 60mg to 50 to 40 to 30 to 20 and cold turkey at 20mg. I didn’t experience any negatives when I did that and I know the only way I can do that is if I’m busy during the day doing things instead of just sitting in my store all day long.
Unfortunately Memantine for some reason had the opposite for me. It made me seek more amphetamines and other drugs. I only used 5mg every other day then 5mg/day and after about two or three weeks I quit using it because it was making things worse.
I know there is very little proof of neurotoxicity from amphetamines in humans unless doses are well over 100mg but I am still using an arsenal of antioxidants and neuroprotective agents. Alcar,na-r-ala, 7,8 dihydroxyflavone, 350mg pomella, EGCg, Curcumin, 8-10g Omegas(2:1 DHA/EPA), 200mcg selenium, 900-1800mg Pharma NAC, 6g vitality C, OptiZinc, tons of magnesium, Lions Mane, etc...
Another thing is my nitric oxide levels are very depleted. This could be coming from my supplementation of HydroxoCobalamin which I just read inhibits NO so I ditched that. Also my mutations show I lack the conversions for Bh4 and other methyls so I added 400mg SamE and I may supplement with oral Bh4. Added 5g fermented beet root powder as well to boost NO.
Edited by John250, 02 October 2018 - 09:31 PM.