Agree; once the brain is loaded up with iron, bloodletting ins't going to provide any real benefit, & even herbal chelators may not have much effect. Hopefully the medical chelators will show promise at salvaging those with early stage Alzheimer's.
An ounce of prevention worth a pound of cure! Maintain good iron homeostasis throughout your life, & hopefully your brain will last as long as your body does.
Keep ferritin out of triple digits and chelate the small amount of free/labile iron with good nutrition (or supps). You'll minimize Fenton reactions and generation of hydroxyl radicals (the most destructive force in the body at the cellular level).
Is protein bound iron (ie IPS) the "same" as heme iron? They are both bound to protein molecules though of different kinds. Does this make them equally safe? My n=1 trial is having great results on 15mg equivalent IPS; no stomach distress which I almost take as a sign that this is the "safe" version of iron.