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Cortisol crushers. adrenocortical Inhibitors

cortisol adrenocortical

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4 replies to this topic

#1 John250

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Posted 20 November 2018 - 05:05 PM


Years and years ago bodybuilders always used a drug called Cytadren the last few weeks before a contest. The body is under extreme stress from a caloric deficit and dangerously low levels of body fat. Cytadren is an anti estrogen but was used mainly for its adrenocortical inhibiting properties. I was curious what happened to it and I did a quick search and it seems there are only 2 adrenocortical inhibitors that exist.

Cytadren (aminoglutethimide)
Metopirone (metyrapone)

I noticed a lot of discussions on this forum about ways to reduce cortisol and these inhibitors seem to come with a host of side effects but what I find odd is there only 2 medications made. I can’t think of any other drug out there where only 2 brands exist.

Edited by John250, 20 November 2018 - 05:07 PM.

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#2 chung_pao

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Posted 21 November 2018 - 12:54 PM

How about just Cissus Quadrangularis or 6-Ketoprogesterone?

They are Glucocorticoid receptor antagonists.
6-KP also has inhibitory effects on mineralocorticoids.

Then there is also 11-Ketotestosterone and Beta-Androstenetriol for potent cortisol inhibitory effects.
You may not expect much, but these are all incredibly potent if used correctly.

The effects I experience are complete absence of urgency and stress, along with lower water retention, giving my muscles a lean look.
And if used with Phenibut, I'm in a state of carefree bliss until withdrawal sets in (be careful with Phenibut).

Other substances with similar effects but weaker are:
Adrenosterone (11-oxo).
7 Alpha Hydroxy DHEA / 7 Beta Hydroxy DHEA.

(Been researching potential Glucocorticoid antagonists the last years.)

Edited by chung_pao, 21 November 2018 - 12:56 PM.

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#3 TheFountain

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Posted 22 November 2018 - 10:23 PM

Tulsi Tea blocks Cortisol for about 8-9 total hours, hence why people take it at night before bed. 



#4 John250

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Posted 23 November 2018 - 04:31 PM

Tulsi Tea blocks Cortisol for about 8-9 total hours, hence why people take it at night before bed.


What dosage? Dosing seems very vast with tulsi.

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#5 TheFountain

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Posted 03 December 2018 - 07:47 AM

What dosage? Dosing seems very vast with tulsi.

Honestly, I just steep the bag in hot water and leave it in there while sipping slow. 

 

I sleep like a babay. 







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