Adding high dose k2 might be prudent if adequate D levels cause calcium issues.
From :
http://www.k-vitamin....php?page=Why_K
"Vitamin K and Cardiovascular Disease
Cardiovascular disease affects millions of people around the world. It is the leading cause of mortality in the western world. The major underlying disease is atherosclerosis. Current medical treatments are often invasive and surgical, and medications can have toxic side effects. Vitamin K is not known to be toxic.
* A key vitamin K dependent protein is matrix Gla protein (MGP), and is the most important inhibitor of arterial calcification – or of plaque build up in arteries. Mice who have been genetically bred without MGP die within weeks due to rupture of their arteries.
* Gla needs an adequate amount of vitamin K available in order to function effectively and inhibit calcium. If Gla has enough vitamin K available to it, it becomes ‘carboxylated’. This is desirable, as it means that your body has enough vitamin K for health.
* Research has measured Matrix Gla Protein in the body and low amounts of Gla are correlated with high arterial calcification scores – a key measure of the extent of heart disease, meaning most folks with heart disease are also vitamin K deficient.
* It is now understood that atherosclerosis and heart disease are part of the vascular-bone axis, and can result from dysregulation of calcium in the body – rather than going to bones and teeth, etc, it ends up in veins and arteries.
* Peer reviewed scientific research indicates that adequate amounts of vitamin K can reverse heart disease.
Research has identified several ways that carboxylation can be disrupted, meaning that heart disease can begin. People with these events should take vitamin K.
1. antibiotics can affect the bacteria in your gut, interfering with the metabolism of vitamin K from food.
2. vaccinations can have the same effect.
3. a diet which is low in green leafy vegetables, meaning your diet doesn’t give you enough vitamin K
4. medications such as warfarin, or coumarin, which is prescribed for blood clots. Warfarin interferes with vitamin K and people taking warfarin often develop heart disease as a result."