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Group Buy for Imidazenil

anxiety imidazenil

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3 replies to this topic

#1 Reformed-Redan

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Posted 03 March 2019 - 01:16 AM


Hello respected nootropic enthusiasts.

 

I am planning on conducting a group buy for Imidazenil. 

 

It's extremely potent and I have a quote for 2000 USD for 100g. 

 

Please do your own research into this compound. It's a highly promising compound that doesn't display issues with tolerance and dependecy. 

 

I found a supplier that is willing to synthesize it over at Alibaba. 

 

I plan to get a 5-10 person group buy. 

 

At 10 people, it's 200 USD for 10g, which will last you forever. 

 

Please familiarize yourself with this amazing benzodiazepine that doesn't cause tolerance to its effects due to partial agonists activity on the GABA-A receptors subtype alpha5. 

 

If you are interested, please post here. It's a fascinating compound to treat anxiety without sedation and other unwanted effects associated from typical full agonists on GABA-A receptors. 

 

Post here if interested.

 

https://en.wikipedia...wiki/Imidazenil

 

Imidazenil[1] is an experimental anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolamflumazenil, and bretazenil.

Imidazenil is a highly potent benzodiazepine receptor partial agonist[2] with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic[3] effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold,[4] and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.

Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety,[5] a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents,[6][7] and as a novel treatment for schizophrenia.[8]



#2 Azet

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Posted 04 March 2019 - 10:55 PM

You can count me in. What is the usual effective dose?

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#3 Reformed-Redan

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Posted 28 March 2019 - 03:43 AM

bump



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#4 Pleb0

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Posted 02 December 2019 - 05:55 PM

Hello! Any update on this? I know it's been 8 months, but I am also curious on ways of acquiring imidazenil, or it's effects.





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