"Conclusion Our study for the first time shows that NR maintains lysosomal acidification and enhances autolysosome clearance via SIRT1 signaling thereby preventing doxorubicin cardiotoxicity.
Given its recognition as an effective dietary supplement to increase NAD + levels and its favorable safety profile, NR may be a potential candidate for clinical trials."
https://www.ncbi.nlm...pubmed/31266854
Edited by Fredrik, 05 July 2019 - 01:22 PM.