• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
              Advocacy & Research for Unlimited Lifespans

- - - - -

Criteria for success of anti-aging therapies

nmn anti-aging nad+

  • This topic is locked This topic is locked
No replies to this topic

#1 LawrenceW

  • Member
  • 385 posts
  • 326
  • Location:California

Posted 07 October 2019 - 04:59 PM




Accurate and physiologically meaningful biomarkers for human aging are key to assessing antiaging therapies. Given ethnic differences in health, diet, lifestyle, behavior, environmental exposures, and even average rate of biological aging, it stands to reason that aging clocks trained on datasets obtained from specific ethnic populations are more likely to account for these potential confounding factors, resulting in an enhanced capacity to predict chronological age and quantify biological age. Here, we present a deep learning-based hematological aging clock modeled using the large combined dataset of Canadian, South Korean, and Eastern European population blood samples that show increased predictive accuracy in individual populations compared to population specific hematologic aging clocks. The performance of models was also evaluated on publicly available samples of the American population from the National Health and Nutrition Examination Survey (NHANES). In addition, we explored the association between age predicted by both population specific and combined hematological clocks and all-cause mortality. Overall, this study suggests (a) the population specificity of aging patterns and (b) hematologic clocks predicts all-cause mortality. The proposed models were added to the freely-available Aging.AI system expanding the range of tools for analysis of human aging.



For many years we have been sharing anecdotal reports about our NAD+ precursor supplementation. We finally have a method to objectively report our progress in our quest to improve our healthspans.


Enter your biomarkers at www.aging.ai and have your blood test results compared against a database of over 200,000 individuals.

  • Enjoying the show x 1

Also tagged with one or more of these keywords: nmn, anti-aging, nad+

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users