45, male, 192lb reasonably fit.
Two weeks ago I started on 2.5mg pf rapa per week intending to run it for four months. I'm at that age where you suddenly notice the ageing process is accelerating. I want to put the brakes on....
I have had keratosis pilaris all my life and had resigned myself to it. I'm fair skinned and have goosebumps on back of arms and top of thighs. Feels very rough / bumpy to the touch. Around day 5 I realised it was clearing up. Now at day 12 and it's even better. Almost completely smooth skin. However the appearance has only slightly improved. Given it's been like that for decades maybe it'll take a lot longer to clear up visually.
I did find this patent from years ago -> https://patents.goog...S20080207672/en
I also realised that my libido has dropped off a cliff. Mentally I'm not feeling the urge and physically erections are less hard and morning wood has all but disappeared. Does rapa affect testosterone pathways?
No other noticeable effects. Perhaps I'm feeling slightly stronger at the gym and a case of medial epicondylitis has cleared up considerably after 6 months or so of no change. But both of those could easily be placebo.
I'm going to halve the dose to 1.25mg and see what happens.