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What is threonine and why does it lift my depression almost instantly?

threonine brain

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#1 iseethelight

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Posted 06 November 2019 - 01:13 AM


I started taking threonine for gut health but I notice it lifts my depression quite a bit within minutes of taking it.  My research only shows vague info about it, nobody seems to know what it does. I don't want to  keep taking it since I don't what it can do to me long term. Any inputs?

Maybe it has an action on the NMDA receptor? I maybe have a low functioning NMDA?



#2 adamh

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Posted 08 November 2019 - 07:42 PM

Its quite harmless, its found in food and is an essential amino acid. I would not over do it but a gram or two per day should be very helpful. In fact I just ordered some after reading more about it.



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#3 BasicBiO

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Posted 19 November 2019 - 11:12 PM

I have been using it for the last 3 days. Initial dose of about 300mg in the morning was shockingly successful in boosting alertness, motivation, and energy. Why? I have no idea as the literature doesn't point to these possibilities. Now at day 3, the positive effects are still there but less dramatic. I suspect homeostasis will even things out but an interesting experiment nonetheless.



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#4 ailsworb

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Posted 30 January 2020 - 03:15 AM

I have the exact same experience with threonine. Not only were the positive cognitive benefits dramatic, but they were very immediate (felt it within 15-20 min taken on an empty stomach).

 

I believe it has something to do with the fact that threonine is necessary for the biosynthesis of P5P, which is essential for the synthesis of dopamine.


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