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How exactly do scientists know that senolytic drugs have successfully killed senolytic cells in mice?

senolytics mice

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#1 osris

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Posted 05 December 2019 - 01:55 PM


At the risk of sounding incredibly stupid, how exactly do scientists know that senolytic drugs have successfully killed senolytic cells in mice? In other words, can the death of senolytic cells be “seen” or apprehended in some way by various scientific measuring devises, or is their death assumed from the positive effects fisetin had on the mice’s physiology etc?

 

Also, how long after the mice taking fisetin did these positive effects manifest—one week, one month, one year after they took it? And in humans how long would these positive effects take to manifest after taking fisetin?



#2 ortcloud

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Posted 06 February 2020 - 10:24 PM

Looks like no one answered your question. I am sure you can find the answer if you just google it if you dont want to wait around for someone to respond.


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#3 osris

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Posted 10 February 2020 - 12:38 PM

Thanks. I tried Google but couldn't find anything. I expect the research is still too new for anyone to be curious enough to want to know the answer. 







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