.
P A Y W A L L E D S O U R C E : Cell_Trends in Biochemical Sciences
ABSTRACT
Senescence is a complex cellular state, which can be considered as a stress response phenotype. However, the mechanisms through which cells acquire and maintain this phenotype are not fully understood. In this paper, it is argued that the unfolded protein response (UPR) may represent a signalling platform that is associated with the major senescence hallmarks.
.
