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Cardiolipin restores Mitochondrial function in mice

mitochondria aging cardiolipin lysosome diphosphatidylglycerol

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#1 SearchingForAnswers

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Posted 19 May 2020 - 07:03 PM


https://phys.org/new...-longevity.html

 

The article states that simple ingestion of cardiolipin (Diphosphatidylglycerol) restored mitochondrial function. Was this only because they were altered mice, or might this work in people?


Edited by SearchingForAnswers, 19 May 2020 - 07:08 PM.


#2 Turnbuckle

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Posted 19 May 2020 - 08:44 PM

 Was this only because they were altered mice, or might this work in people?

 

 

They were worms not mice. And they were mutants as well, thus this only showed that cardiolipin is necessary for proper mito operation, something already known. The discovery was of apparent crosstalk between mitochondria and lysosomes, where mitochondria go to die. There is already known communication via the pink/parkin pathway, which tells lysosomes when to eat mitochondria.


Edited by Turnbuckle, 19 May 2020 - 08:47 PM.


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Also tagged with one or more of these keywords: mitochondria, aging, cardiolipin, lysosome, diphosphatidylglycerol

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