• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
              Advocacy & Research for Unlimited Lifespans


Cardiolipin restores Mitochondrial function in mice

mitochondria aging cardiolipin lysosome diphosphatidylglycerol

  • Please log in to reply
1 reply to this topic
⌛⇒ current fundraiser: B.A.S.E Victor @ OpenCures

#1 SearchingForAnswers

  • Member
  • 209 posts
  • 36
  • Location:KY
  • NO

Posted 19 May 2020 - 07:03 PM



The article states that simple ingestion of cardiolipin (Diphosphatidylglycerol) restored mitochondrial function. Was this only because they were altered mice, or might this work in people?

Edited by SearchingForAnswers, 19 May 2020 - 07:08 PM.

#2 Turnbuckle

  • Member
  • 3,887 posts
  • 1,603
  • Location:USA
  • NO

Posted 19 May 2020 - 08:44 PM

 Was this only because they were altered mice, or might this work in people?



They were worms not mice. And they were mutants as well, thus this only showed that cardiolipin is necessary for proper mito operation, something already known. The discovery was of apparent crosstalk between mitochondria and lysosomes, where mitochondria go to die. There is already known communication via the pink/parkin pathway, which tells lysosomes when to eat mitochondria.

Edited by Turnbuckle, 19 May 2020 - 08:47 PM.

sponsored ad

  • Advert
Click HERE to rent this MEDICINES advertising spot to support LongeCity (this will replace the google ad above).

Also tagged with one or more of these keywords: mitochondria, aging, cardiolipin, lysosome, diphosphatidylglycerol

2 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

    Bing (2)