2 replies to this topic

[faxmulder]

Hi guys,

I’m a “control freak”, with a tendency to over-analyze and plan everything, trying to foresee every possible scenario and control all the details. This can be quite exhausting to be honest. That goes without saying that I have a strong perfectionist attitude.

Is there any supplement that could help me?

Thanks a lot!

[gamesguru]

magnesium, calcium, and authentic green tea

 

if that fails you juggle more powerful stuff until things start to click... NAC, turmeric, inositol, st johns, zinc/multi, lemon balm/mangnolia, ashwagandha, exercise, flaxseed, ...

 

whatever you are suffering, if it a common thing others suffer from (besides aging itself) there are likely good choices already out there which bring yet some relief

[Rorororo]

it seems like you have high glutamate

 

https://www.ncbi.nlm...les/PMC4425334/

 

Here is how to lower it:

 

Glutamic Acid Decarboxylase (Gad) - When our Glutamate is too high, GAD is needed to convert Glutamate into Gaba. Some have a deficiency in this enzyme either through Antibodies being created against it. or deficiency in the diet, like not getting enough B6, Taurine and other nutrients.

GABA-Transaminase Enzyme- Some people with G/G imbalance have no problem creating the Gaba, they just have a problem holding onto it, GABA transaminase enzyme, similar to GAD but in reverse, converts Gaba back into Glutamate if you have "overactive" GABA-Transaminase Enzymes this can cause G/G imbalance.

Upregulated Glutamate / Downregulated Gaba Receptors - Unlike the above conditions Downregulated Gaba receptors and Upregulated Glutamate ones are usually (not always) induced by alcohol or drugs. For example, If you abuse alcohol for a protracted period of time, you will induce a downregulated GabaA site and upregulate Glutamate, this is what causes grand mal seizures in alcoholics.

Before I show some treatments, please note, most Gaba drugs/supplements can be abused, if you do abuse them you can screw up your Gaba production even further create a dependency/addiction and make fixing your Gaba receptors very hard.

Glutamic Acid Decarboxylase Supplements

Vitamin B6 or (P5P) - Adequate B6 is essential to produce enough of this enzyme.

Taurine - Another supplement required for the correct function of GAD

GAD Antibody Treatment - If your immune system is stopping GAD production, Immunosuppressants are typically used. This is not something you want to self treat if you suspect this is your issue, you should 100% have this checked out at your Doctors and use prescribed treatment only.

GABA-Transaminase Enzyme Inhibitor

Lemon Balm Extract or Rosemary Extract - The active ingredient in these 2 herbs is Rosmarinic acid which is proven to slow the rate Gaba is converted back into Glutamate

 

Glutamate DownRegulators

Agmatine - Modified Amino Acid potent at downregulating both Glutamate and Opiode sites.

Magnesium - Electrotyle important in hydration and also potent Glutamate down regulator.

Memantine - Agmatine's Pharmaceutical cousin Glutamate downregulation

 

 

I stole this from:

 

https://www.reddit.c...h_gaba/ffxlmzu/

 

Now, lets use process of elimination:

 

Do you also suffer from anxiety?  

Edited by Rorororo, 25 May 2020 - 08:26 PM.