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mTOR inhibitors and muscle mass

rapamycin mtor fasting ketosis

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#1 NickNick

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Posted 31 May 2020 - 11:09 PM


In order to reduce mTOR, I am doing a low carb diet plus a weekly 36 hour fast. I am also considering taking spermadine or rapamycin. 

 

My concern it that if I reduce mTOR, would I be in a permanently catabolic state that will lead to loss of muscle mass? If this is true then perhaps cycling between longer periods of low mTOR and shorter periods of high mTOR might be a good idea. Giving the body and anabolic period that can be used to build muscle.  


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