2 replies to this topic

[OlderThanThou2]

Interesting study done on cocoa polyphenols, that showed an increase in stem cells. They tested 2 cocoa supplements, one low in polyphenols, one with high polyphenols ( 42 times more ). The high polyphenol group had 2.2-8 times more CACs than the other:

 

https://core.ac.uk/d...df/81206465.pdf

 

 

Mobilization of functionally unaltered CACs. After 30- day HiFI, CD34/KDR-CACs increased 2.2-fold and CD133/KDR-CACs increased 8.0-fold, relative to LoFI control (each p 0.001) (Fig. 3). Similar to FMD effects, CD34/KDR-CACs, but not CD133/KDR- CACs, were significantly increased after intake of LoFI, as compared with baseline

 

The low polyphenols cocoa affected only CD34/KDR-CACs.

 

This makes me wonder if replacing olive oil in the diet for cocoa powder would  make sense, all the more that cocoa is high in stearic acid which promotes mitochondria fusion, Stearic acid is also converted to oleic acid.

 

Perhaps adding an olive supplement instead of the olive oil could be a good idea. This one for instance is rich in Oleanolic Acid, which has been shown in vitro to boost telomerase 5.9 fold:

https://www.carotec....-Power/specials

 

There about 30 times more Oleanolic Acid in 2 pills than in a daily dose of 30g olive oil.

Edited by OlderThanThou2, 01 September 2020 - 08:31 AM.

[protoject]

Wow this would be pretty awesome. About your commment w adding olive oil, I'm wondering if there are fat soluble polyphenols in the cocoa that the olive oil might increase the absorption of. I wish cocoa was high in oleamide, lol. Also, if I took cocoa I would want the xanthines removed [caffeine, theobromine, theophylline].

[OlderThanThou2]

Not sure about removing the theobromine. It dilates the blood vessels, it's part of the beneficial effect of cocoa, contrary to coffee. Personally I prefer cocoa to coffee, all the more that there is a study that showed that coffee is less beneficial to men than women.

 

https://link.springe...0654-018-0359-y

 

 

Coffee and tea intake have been associated with reduced mortality, but no studies have investigated possible substitution effects. The relationship of mortality with coffee, tea, and substituting coffee with tea was investigated in the Netherlands Cohort Study. In 1986, 120,852 men and women aged 55–69 years provided information on dietary and lifestyle habits. Mortality follow-up until 1996 consisted of linkage to Statistics Netherlands. Multivariate case-cohort analyses were based on 8665 deaths and 3166 subcohort members with complete data on coffee, tea and confounders. Higher coffee intake was significantly, nonlinearly related to lower overall and cause-specific mortality in women. In men, coffee was significantly positively related to cancer and cardiovascular mortality, and inversely to respiratory and other causes of death. Tea intake was significantly, nonlinearly related to lower overall, cancer and cardiovascular mortality in men, but showed no association with mortality in women. In substitution analyses, increasing the proportion tea (replacing coffee with tea) was significantly and nonlinearly related to lower overall, cancer and cardiovascular mortality in men, but in women higher tea proportions were positively associated with overall mortality (and most causes of death). This study suggests that for men, compared to exclusive coffee drinkers, those drinking 30–50% tea showed the lowest mortality; any tea drinking seemed better than only coffee. For women, those who drank exclusively coffee or drinking up to 40% tea had the lowest mortality, but those drinking higher percentages of tea were at increased mortality risk [HR = 1.41 (95% CI 1.01–1.99) for 80–100% tea compared to exclusive coffee drinkers].