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what is the concensus on chocolate and parkinsons?

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4 replies to this topic

#1 ironfistx

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Posted 28 August 2021 - 11:39 PM


Awhile back there was a thread that posited a few opinions:

 

1) People with PD consume more chocolate than those without

2) People with PD consumed more chocolate before onset than those without

3) Chocolate [may] cause some kind of dopamine oversensitization in people who are predisposed

 

The general advice was to avoid chocolate if worried.

 

Did any more detail about this appear?



#2 Ames

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Posted 21 January 2022 - 10:56 PM

I don't have any research to back this up, but came to the personal conclusion that chocalate feels ever so slightly neurotoxic to me via its stimulation action. Which is undoubtedly broad. I still eat it, but only occassionaly. 

 

Recently, I noticed that I reliably get migraines within a day of eating chocolate. I am prone to them, but had never prior noticed chocolate having this effect.


Edited by Ames, 21 January 2022 - 11:10 PM.


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#3 sensei

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Posted 03 February 2022 - 07:05 PM

Parkinson's Disease is caused by systemic inflammation, Elevated mtorc1 signalling, and deficient autophagy.

Rapamycin, an mtorc1 inhibitor, prevents PD in a mouse model of the disease.

https://www.scienced...50916184909.htm

The NLRP3 inflammasome, implicated in MS is also implicated in PD.

:text=We%20found%20that%2C%20in%20some,to%20brain%20inflammation%20in%20PD' class='bbc_url' title='External link' rel='nofollow external'>https://www.michaelj...lammation in PD.

MTORC1 inhibition lowers NLRP3 activity.

Of note: In a small investigational study for the use of rapamycin in people with MS, rapamycin reduced or reversed MS symptoms and also reduced the lesion size after 6 months of administration.

https://pubmed.ncbi....h.gov/30219744/
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#4 kurdishfella

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Posted 03 February 2022 - 08:19 PM

Probably depends on how much chocolate you ingest 



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#5 TheFountain

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Posted 07 February 2022 - 08:57 PM

It's the heavy metals in most commercial chocolates, Cadmium and or lead. Find a cocoa that is low in Cadmium and lead and then find a study using this same low HM Cocoa, and you will likely find no correlation with Parkinsons.

 

In fact, Michael J Fox spoke extensively about the fact that he believes his Parkinsons came from drinking contaminated well water as a child. Contaminated with what? Heavy Metal!

 

And no, not the kind you bang your head to. 






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