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Centrophenoxine Risk-Benefit Analysis

centrophenoxine brain health

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3 replies to this topic

#1 APBT

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Posted 05 October 2022 - 01:18 PM


https://brain.foreve...entrophenoxine 



#2 Harkijn

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Posted 05 October 2022 - 03:23 PM

Mmmm, Page Not Found ....  ?



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#3 APBT

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Posted 05 October 2022 - 11:05 PM

This should work:  https://brain.foreve...Centrophenoxine

 



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#4 Fafner55

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Posted 06 October 2022 - 08:11 PM

Be aware that the DMAE moiety of centrophenoxine can enter the choline synthesis cycle and consequently increase the brain’s acetylcholine supply. In my case, 300 mg/day centrophenoxine led to feelings of depression within a week, probably through an increase in choline levels. I discontinued taking it after 10 days.

 

Acetyl-L-Carnitine might work by the same mechanism. ALCAR has a chemical structure that is similar to choline, but unlike choline, carnitine is not a neurotransmitter and has fewer reported side effects. It has been shown to reduce lipofuscin levels in aged rats.
  1. "Effects of Acetyl-L-Carnitine on the Brain Lipofuscin Content and Emotional Behavior in Aged Rats" (1988) https://doi.org/10.1254/jjp.48.365
  2. "Reduced lipofuscin accumulation in senescent rat brain by long-term acetyl-L-carnitine treatment" (1989) https://doi.org/10.1...4943(89)90035-6
  3. “Anti-aging Effects Of Acetyl-L-Carnitine” (2000) https://www.lifeexte...e/2000/5/cover2
 

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