https://brain.foreve...entrophenoxine
Centrophenoxine Risk-Benefit Analysis
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APBT
, Oct 05 2022 01:18 PM
centrophenoxine brain health
3 replies to this topic
#1
Posted 05 October 2022 - 01:18 PM
#2
Posted 05 October 2022 - 03:23 PM
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#4
Posted 06 October 2022 - 08:11 PM
Be aware that the DMAE moiety of centrophenoxine can enter the choline synthesis cycle and consequently increase the brain’s acetylcholine supply. In my case, 300 mg/day centrophenoxine led to feelings of depression within a week, probably through an increase in choline levels. I discontinued taking it after 10 days.
Acetyl-L-Carnitine might work by the same mechanism. ALCAR has a chemical structure that is similar to choline, but unlike choline, carnitine is not a neurotransmitter and has fewer reported side effects. It has been shown to reduce lipofuscin levels in aged rats.
- "Effects of Acetyl-L-Carnitine on the Brain Lipofuscin Content and Emotional Behavior in Aged Rats" (1988) https://doi.org/10.1254/jjp.48.365
- "Reduced lipofuscin accumulation in senescent rat brain by long-term acetyl-L-carnitine treatment" (1989) https://doi.org/10.1...4943(89)90035-6
- “Anti-aging Effects Of Acetyl-L-Carnitine” (2000) https://www.lifeexte...e/2000/5/cover2
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