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Resveratrol users


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#1 DukeNukem

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Posted 27 December 2007 - 06:50 PM


Resveratrol has clearly attracted a lot of attention to this site, with a lot of new faces showing up after all the hot news last year and this year. I'm curious, though, if those people who have placed a big bet of RSV are also taking other supps. As promising as RSV seems to be, it certainly isn't a one-stop solution. So, of the RSV users here, how many other supps do you take daily on average? Me, I take about 80 pills daily, and about 15 powdered supps.

#2 missminni

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Posted 27 December 2007 - 07:55 PM

Resveratrol has clearly attracted a lot of attention to this site, with a lot of new faces showing up after all the hot news last year and this year. I'm curious, though, if those people who have placed a big bet of RSV are also taking other supps. As promising as RSV seems to be, it certainly isn't a one-stop solution. So, of the RSV users here, how many other supps do you take daily on average? Me, I take about 80 pills daily, and about 15 powdered supps.

I don't take as many supplements as most people here do. Prior to doing Res I did about 10 supplements a day.
Pregnenolone (which I stopped and now have started up but reduced the amount and staggered the time)
L-Carnitine, 500 mg
Glucosamine, 3 to 4 grams
coQ10, 200 mg
selenium 200 mcg (which I have since stopped after reading about it here)
alpha lipoic acid, (which I need to re-order)
Lutein (just started for eyes)
Billberry (just started for eyes)
Vit D - which I stopped because I eat a lot of D fortified dairy
Vit A - which I also stopped because I eat lots of dark greens and cilantro
Indole 3-Carbinol - 200 mg - which I totally forgot to take these past few weeks
omega 3 - used to take, have to get - in fact can somebody recommend a good brand please
B 12 3000 mcg. sublinguals when I remember
B complex from Thorne that I ran out of a while ago.

and of course my most favorite fresh aloe vera almost every day

I have mixed feelings about vitamins and supplements. Sometimes I think they are crucial, other times
I think they are overkill.

One thing I believe is to change up often as the body gets used to routine, as it does with exercise too, and that's not necessarily a good thing. Of course, I have nothing to back up any of my
opinions, except I think the part about routine and exercise is a fact. If your body gets too used to
the same exercise it begins to expect it and you reach a plateau instead of
continued advancement. That's why cross training is so effective.
Having said that, I better get my butt to the gym now. This is pure procrastination.



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#3 DukeNukem

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Posted 27 December 2007 - 08:15 PM

missminni,

I'm not really talking about the standard vitamins and minerals, but non-typical supps not taken by the average masses (e.g. CoQ10, pomegrate extract, ALT-711, IP-6), or higher levels of standard supps, like C, D, and/or K.

BTW, the type of D (D2) used in fortified foods has very low bioavailabilty, based on numerous sources I've read. You really need to rely on direct sunshine and/or D3 supps.

And what did you read that coaused you to change your mind on selenium?!?! This is proven conclusively to be one of the best cancer prevention molecules humans can take.

#4 missminni

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Posted 27 December 2007 - 08:30 PM

missminni,

I'm not really talking about the standard vitamins and minerals, but non-typical supps not taken by the average masses (e.g. CoQ10, pomegrate extract, ALT-711, IP-6), or higher levels of standard supps, like C, D, and/or K.

BTW, the type of D (D2) used in fortified foods has very low bioavailabilty, based on numerous sources I've read. You really need to rely on direct sunshine and/or D3 supps.

And what did you read that coaused you to change your mind on selenium?!?! This is proven conclusively to be one of the best cancer prevention molecules humans can take.


I actually read that selenium supplementing can be harmful:

http://www.atsdr.cdc.gov/tfacts92.html
Selenium has both beneficial and harmful effects. Low doses of selenium are needed to maintain good health. However, exposure to high levels can cause adverse health effects. Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and diarrhea. Chronic oral exposure to high concentrations of selenium compounds can produce a disease called selenosis. The major signs of selenosis are hair loss, nail brittleness, and neurological abnormalities (such as numbness and other odd sensations in the extremities).

I actually was having numbness in my toes and fingers at one point.
I would like to get my supplements in as natural a form as possible. I do worry about over supplementing.
I usually get plenty of sunshine, but in the winter, I should supplement with D3. Thanks for the reminder.
ETA~re:selenium - I was also having hair loss, which I attributed to the pregnenolone. Maybe it was the selenium.

Edited by missminni, 27 December 2007 - 08:34 PM.


#5 tintinet

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Posted 27 December 2007 - 08:54 PM

Resveratrol has clearly attracted a lot of attention to this site, with a lot of new faces showing up after all the hot news last year and this year. I'm curious, though, if those people who have placed a big bet of RSV are also taking other supps. As promising as RSV seems to be, it certainly isn't a one-stop solution. So, of the RSV users here, how many other supps do you take daily on average? Me, I take about 80 pills daily, and about 15 powdered supps.


Ya. Everthing, almost, I can get: NtBHA, pyridoxamine, ALT-711, metformin, r-lipoic acid, many herbals and gram quantities of t-resv., both extract- mostly 99% pure
and 99%+ pure synthetic, etc.

#6 maxwatt

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Posted 27 December 2007 - 10:16 PM

missminni,

I'm not really talking about the standard vitamins and minerals, but non-typical supps not taken by the average masses (e.g. CoQ10, pomegrate extract, ALT-711, IP-6), or higher levels of standard supps, like C, D, and/or K.

BTW, the type of D (D2) used in fortified foods has very low bioavailabilty, based on numerous sources I've read. You really need to rely on direct sunshine and/or D3 supps.

And what did you read that coaused you to change your mind on selenium?!?! This is proven conclusively to be one of the best cancer prevention molecules humans can take.


I actually read that selenium supplementing can be harmful:

http://www.atsdr.cdc.gov/tfacts92.html
Selenium has both beneficial and harmful effects. Low doses of selenium are needed to maintain good health. However, exposure to high levels can cause adverse health effects. Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and diarrhea. Chronic oral exposure to high concentrations of selenium compounds can produce a disease called selenosis. The major signs of selenosis are hair loss, nail brittleness, and neurological abnormalities (such as numbness and other odd sensations in the extremities).

I actually was having numbness in my toes and fingers at one point.
I would like to get my supplements in as natural a form as possible. I do worry about over supplementing.
I usually get plenty of sunshine, but in the winter, I should supplement with D3. Thanks for the reminder.
ETA~re:selenium - I was also having hair loss, which I attributed to the pregnenolone. Maybe it was the selenium.


Too much selenium does cause hair loss; in Hawaii there is a plant that concentrates selenium. When horses eat it, their manes and tails fall off.

I only supplement with EPA if I'm not getting cold water fish 3 times a week: salmon, tuna, herring.
D3, 6000 to 8000 from the autumn equinox to the spring equinox, and half that in the summer.
I believe acetyl-l-carnitine may not be necessary for mitochondrial health if one is supplementing with resveratrol in large amounts; I've recently discontinued it with no discernible difference in power output on a bicycle ergonometer.
PBN and R-alpha-lipoic acid I've been taking, but wonder about the need for them.
A high-gamma E, but only 200 mg. That I believe puts me near the peak of the inverted U shaped response curve for this supplement.
Vitamin K, but eating as much kale and broccoli as I do, it might be overkill.
Bilberry, lutein, xeanthin, curcumin. I'm not currently using silymarin,but I have for long periods.
A low dose multi; I find high doses of B vitamins cause depression.
I eat enough ginger it should be considered a supplement.
I'm looking into magnesium orotate.
CoQ10. I suspect its use "immunizes" you against Parkinson's.
DHEA 25 mg: approximately two weeks on, two weeks off. As Missmini said, you have to vary things or your body adjusts.
Rhodiola. I like the way it feels. It was life extending in fruit flies, but that is scant evidence for anything.

I do think the use of resveratrol in high doses obviates the need for many other supplements, and that many of us take too many supplements for the wrong reasons.

I'm surprised the American Psychological Association hasn't come up with a diagnostic category for excessive supplement users.

#7 missminni

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Posted 28 December 2007 - 12:44 AM

Too much selenium does cause hair loss; in Hawaii there is a plant that concentrates selenium. When horses eat it, their manes and tails fall off.

I only supplement with EPA if I'm not getting cold water fish 3 times a week: salmon, tuna, herring.
D3, 6000 to 8000 from the autumn equinox to the spring equinox, and half that in the summer.
I believe acetyl-l-carnitine may not be necessary for mitochondrial health if one is supplementing with resveratrol in large amounts; I've recently discontinued it with no discernible difference in power output on a bicycle ergonometer.
PBN and R-alpha-lipoic acid I've been taking, but wonder about the need for them.
A high-gamma E, but only 200 mg. That I believe puts me near the peak of the inverted U shaped response curve for this supplement.
Vitamin K, but eating as much kale and broccoli as I do, it might be overkill.
Bilberry, lutein, xeanthin, curcumin. I'm not currently using silymarin,but I have for long periods.
A low dose multi; I find high doses of B vitamins cause depression.
I eat enough ginger it should be considered a supplement.
I'm looking into magnesium orotate.
CoQ10. I suspect its use "immunizes" you against Parkinson's.
DHEA 25 mg: approximately two weeks on, two weeks off. As Missmini said, you have to vary things or your body adjusts.
Rhodiola. I like the way it feels. It was life extending in fruit flies, but that is scant evidence for anything.

I do think the use of resveratrol in high doses obviates the need for many other supplements, and that many of us take too many supplements for the wrong reasons.

I'm surprised the American Psychological Association hasn't come up with a diagnostic category for excessive supplement users.

LOL funny but so true.
The problem with supplementing is that you really don't know how much of it you personally need,
and I probably already had enough selenium in my diet. That's why I was losing hair and having numbness in my fingers and toes. Too much of a good thing is not a good thing. Common sense and moderation seem to go on vacation when it comes to supplements. I am as guilty of that as anybody. I only hope the people taking these vast amounts of supplements and vitamins don't have adverse effects later in life.
I have a theory, and it 's the reason I never took multi vitamins and in fact I never really took vitamins. If you give your body all those vitamins, it will forget how to extract them from the food you eat. You will make your body lazy. I know that sounds simplistic but often the very simplest of ideas is true. Taking anti-oxidants made sense to me because I live in such a nasty environment (a busy urban one with heavy car exhaust fumes etc), and supplementing with pregnenolone as I aged, since the decline of it in your system brings on aging, seemed logical, as does resveratrol. If you know you don't eat enough cruciferous vegetables then taking indole 3 carbinol makes senses. But if you eat your broccoli and kale everyday, why take it? Of course, this bring me right back to the beauty of aloe.


#8 sUper GeNius

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Posted 28 December 2007 - 02:28 AM

Resveratrol has clearly attracted a lot of attention to this site, with a lot of new faces showing up after all the hot news last year and this year. I'm curious, though, if those people who have placed a big bet of RSV are also taking other supps. As promising as RSV seems to be, it certainly isn't a one-stop solution. So, of the RSV users here, how many other supps do you take daily on average? Me, I take about 80 pills daily, and about 15 powdered supps.



It's really hard to know what to take and in what doses. I've been supplementing since the early 80's after I read Durk Pearson's first book, turned orange a few times. (those who know the book know why.)

I wish there was a Wiki here that listed some of the best supplements to take and a link to the evidence supporting it, rather than having to sift through all the info here.

I asked before, but perhaps you did not see my post Duke. Could you list what you currently take?

#9 VP.

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Posted 28 December 2007 - 02:55 AM

Hi Duke,
I take the usual mix found on most supplement lists on this board. No Metaformin, NtBHA or ALT 711 though. Whats going on with ALT-711? Alteon stock is in the dumps (down 77%)

#10 edward

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Posted 28 December 2007 - 04:08 AM

I take roughly 60 different supplements that the general population does not take (maybe less, probably more, depending on how you define "the general population") most are now in bulk powders, though I take capsules and liquids of things that are very hard to measure out in powder form. I make up little twice daily cups of roughly 30 grams worth of powders each and take these with fruit juice or now blend with whey protein (either way it is not a pleasant experience but capping everything seems to be a waste of time and buying precapped preparations seems to be a waste of money, though for awhile I was making custom capsule blends and that was not bad) One day if I get industrious and bored, I will compile a list along with dosages and post in the supplement regime subforum... Btw Resveratrol or rather SIRT activators are the supplements I remain the most excited about.

edit: the usual

Edited by edward, 28 December 2007 - 04:11 AM.


#11 edward

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Posted 28 December 2007 - 04:25 AM

I'm surprised the American Psychological Association hasn't come up with a diagnostic category for excessive supplement users.


It's only a matter of time, I am sure we could be classified as having characteristics of obsessive compulsive disorder, some sort of body dysmorphic disorder, elements of addiction, elements of eating disorders... etc. etc. it's a multi-faceted psychological syndrome :-D

#12 krillin

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Posted 28 December 2007 - 05:05 AM

And what did you read that coaused you to change your mind on selenium?!?! This is proven conclusively to be one of the best cancer prevention molecules humans can take.


It has a U-curve, and even worse, we don't know with certainty what the ideal blood level is because the fricking scientists broke down baseline selenium by tertile but didn't bother to do so after supplementation. My best guess is here.

In order to be able to squeeze MeSC supplements (the best form) into my diet, I'm having to purge my diet of brazil nuts. I thought it was bad enough that I took all supplements individually, now I have to make my own nut blend too.

A high-gamma E, but only 200 mg. That I believe puts me near the peak of the inverted U shaped response curve for this supplement.


Do you have any references? I'm blindly supplementing Jarrow's 300 mg gamma, 100 mg delta, 34 mg alpha.

If you give your body all those vitamins, it will forget how to extract them from the food you eat.


http://books.nap.edu...i...10&page=158

Evidence of systemic conditioning (the accelerated metabolism or excretion of ascorbic acid) exists from uncontrolled observations in humans following abrupt discontinuation of prolonged, high-dose vitamin C supplementation (Rhead and Schrauzer, 1971; Siegel et al., 1982). Omaye et al. (1986) showed increased turnover of plasma ascorbic acid in apparently healthy human adults who abruptly decreased their vitamin C intake from 605 to 5 mg/day. Two other studies showed that high intakes resulted in increased clearance but did not result in blood levels lower than normal (Schrauzer and Rhead, 1973; Tsao and Leung, 1988). Other studies have reported no rebound scurvy or excessive lowering of ascorbate blood levels after cessation of high intakes (Hoffer, 1973; Ludvigsson et al., 1979). Evidence that rebound scurvy may appear in infants whose mothers ingested large doses of vitamin C during pregnancy is limited to one anecdotal report of 2 infants (Cochrane, 1965). Overall, the evidence is inconsistent and does not suggest that systemic conditioning occurs to any significant extent in infants and adults.



#13 zoolander

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Posted 28 December 2007 - 05:32 AM

Australia is pretty new to dietary supplements and most people only kno about the basics like multi's and C & E.

Stuff I use that is not generally used:
-melatonin
-selegiline
-thyroxine (on big days)
-biosil
-huperzine or galantamine
-recently just started with vinpocetine again (40mg)
-phenibut (once a month)
-Micellar protein
-Amylocel (Waxy Maize Starch) with BCAA's
-different types of whey proteins from Hydrolyzed to Cold filtered isolates

#14 missminni

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Posted 28 December 2007 - 09:55 PM

And what did you read that coaused you to change your mind on selenium?!?! This is proven conclusively to be one of the best cancer prevention molecules humans can take.


Hi Duke
Pursuant to our discussion about selenium possibly being harmful if overdosed and the comments to that effect
I just checked to find what foods are rich in selenium. Most of them (the ones in green) are foods I eat often, some on a daily basis.
wheat germ, seafood and shellfish, beef liver and kidney, eggs, sunflower and sesame seeds, brazil nuts, mushrooms, garlic, onions, and kelp.

Since I stopped supplementing with selenium (200mcg), the numbness in my fingers and toes has ceased (which BTW I was attributing to taking resveratrol because I started taking it about the same time I stopped the selenium) and my hair has stopped falling out (which I thought was due to the pregnenolone, which since I have started taking again with no hair loss at all).

I think we would all be wise when supplementing to analyze our diet for that particular substance to avoid overdosing.
Too much of a good thing can be bad.
When I read about the enormous amounts of supplements and vitamins people here take on a daily basis, I can't help
but wonder about the wisdom of it. I know many of you are diligent about getting blood work and seeing doctors etc, but
getting your nutrition through eating properly and then adding supplements where your diet fails to, is probably
the healthier way to go. It seems the majority here are young men, so I imagine that taking a pill or powder rather than shopping and preparing a meal is a much more attractive way to get nutrition. I just hope as you get older it doesn't create any unforseen problems.
Have there been any long term studies on that issue?


#15 scorpe

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Posted 28 December 2007 - 11:15 PM

Just returned from a short ski vacantion in Austria (did not ski for 40 years and it proved once learned you will never forget :-D ).

Beside resv. I use saw palmetto, DHEA 25mg 5 days a week, Melatonin 1 mg not on a regular base, boron, fish oil, boswellia, rhodiola, acai, pomegranate, selenium 100mg not every day, total E (aor), q10 , magnesium, R-lippoic acid,n-acetyil cys., cranberry, host defense (new chapter), manganese, b3, b6 , b multi, vit. c, D3, shitake, glocosamine, multi vit. and some others not on a regular base.

Edited by scorpe, 28 December 2007 - 11:16 PM.


#16 sablystone

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Posted 30 December 2007 - 02:44 AM

Hello Duke,

100mg longevinex twice daily
1000mg C three times daily
500mg quercitin three times daily
4000 IU D3
85mg aspirin
purity products HLA
purity products super greens multi with omega three times daily
1000mg Carlson super DHA/EPA three times daily
4 capsules daily Xtendlife total balance mens multi daily
10g of L-arginine on empty stomach before sleep
testosterone pellets implanted under abdominal skin, replaced every 5-6 months

started this over a year ago, havn't been sick, had a cold, or missed a day of work in over a year. See 50 plus sometimes incredibly sick patients daily, shaking hands and face to face with everyone of em.

Edited by sablystone, 30 December 2007 - 02:59 AM.


#17 tintinet

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Posted 02 January 2008 - 08:01 PM

Hello Duke,

100mg longevinex twice daily
1000mg C three times daily
500mg quercitin three times daily
4000 IU D3
85mg aspirin
purity products HLA
purity products super greens multi with omega three times daily
1000mg Carlson super DHA/EPA three times daily
4 capsules daily Xtendlife total balance mens multi daily
10g of L-arginine on empty stomach before sleep
testosterone pellets implanted under abdominal skin, replaced every 5-6 months

started this over a year ago, havn't been sick, had a cold, or missed a day of work in over a year. See 50 plus sometimes incredibly sick patients daily, shaking hands and face to face with everyone of em.


Living dangerously, no? I trust yer washing yer hands in between them sick patients?

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#18 sablystone

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Posted 03 January 2008 - 03:00 AM

Hello Duke,

100mg longevinex twice daily
1000mg C three times daily
500mg quercitin three times daily
4000 IU D3
85mg aspirin
purity products HLA
purity products super greens multi with omega three times daily
1000mg Carlson super DHA/EPA three times daily
4 capsules daily Xtendlife total balance mens multi daily
10g of L-arginine on empty stomach before sleep
testosterone pellets implanted under abdominal skin, replaced every 5-6 months

started this over a year ago, havn't been sick, had a cold, or missed a day of work in over a year. See 50 plus sometimes incredibly sick patients daily, shaking hands and face to face with everyone of em.

Alcohol gel, all the way !! Soap and water's not bad either !

Living dangerously, no? I trust yer washing yer hands in between them sick patients?






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