I tried a homemade Resveratrol cream (aveno + resveratrol) for about a week and it really dried out and began to exfoliate my skin. Stopped it and my skin returned to normal. Normal for me is a little dry.
Oral Resveratrol doesn't seem to dry out my skin though any more than normal that is.
Just a note, topical Tretinoin, or Retin-A, arguably one of the best antiaging creams for skin does significantly dry your skin (at least it does mine) so this may not be a sign of bad things.
I agree about that aspect of it being a good thing when applied topically. I use it like that too, and like it. But I moisturize afterwards. I am just wondering why in general, my skin is drier than usual all over, especially noticeable around the cuticles.
Both my friends who just started using it in Hi doses had the same observation of their own skin. Do you think it might just affect women that way? Maybe an estrogen interaction?
The estrogen connection makes sense and I would be willing to bet that that is the reason. Obviously this would have more of an effect on women.
Are we thinking the resveratrol reduces estrogen? According to this study, estrogen appears to prevent both dry skin and wrinkling, so a reduction could cause drier skin:
http://www.ncbi.nlm..../pubmed/9080894
CONCLUSION: These results strongly suggest that estrogen use prevents dry skin and skin wrinkling, thus extending the potential benefits of postmenopausal estrogen therapy to include protection against selected age- and menopause-associated dermatologic conditions.
But according to this article, resveratrol is a form of estrogen:
http://www.scienceda...71219062019.htmResearchers at Northwestern University Medical School have found that a chemical in red wine believed to help reduce risk for heart disease is a form of estrogen. The substance, resveratrol, is highly concentrated in the skin of grapes and is abundant in red wine.
If estrogen reduces dry skin, and resveratrol is a form of estrogen, then resveratrol should not be causing dry skin--that is, if I'm interpeting this information correctly.
Anecdotal: Every day, I ingest resveratrol orally, take estrogen (ERT) and apply tretinoin. My skin isn't the least bit dry (or wrinkled). If anything, it's oily--and I'm fifty.
Edited by luminous, 18 February 2008 - 01:50 AM.