I did try the version that is currently available and it works. The first time it didn't, I suppose because I placed the files in an encrypted (TrueCrypt) folder.
If you can reproduce the failure please tell me more about it.
This is useless anyway, better to store it there afterwards and restart your computer. I must say that I like the comprehensive overview, especially if compared against the navigation prone 23andme user interface. And it has more information. On the flip-side, if you are concerned about security (wearing tin-foil hats or not), I'm sure this program currently does not offer the same level of security that is provided by 23andme and submitting some fake data would be a good thing to obfuscate ISP URL logs.
23andMe needs strong security since they store your information, need to keep it linked to your name/email, and are in the business of making it accessible. That large central repository makes a very attractive target. Promethease has no need to store your information, and has no central target for hackers. SNPedia may eventually need to scrub its logs, but I think that is still a bit premature, relative to the value those logs provide me.
Furthermore, in general, I think that risks > factor x10 should be taken seriously, below that it's just some form of indication that can be used to adapt lifestyle for compensation. Any more thoughts on this?
Hard and fast rules are too simplistic. Firstly 10x is only a magic number because of how many fingers you have. A 20x risk factor may not matter if there is simply nothing that can be done, or if the effect isn't medical (ie 50x risk of freckles). 10x risk matters more for semi-common diseases, then for truely rare ones (your odds of disease X just went from 1 in 10 billion to 1 in 1 billion). What matters most is the ill defined concept of 'actionableness'. This is most relevant for medicines, since they influence future decisions, and this is why the box about medicines is above the box about medical conditions.
Hmmm, given the current culture and structure of society, you don't need to display that kind of behaviour while still being legitimately concerned about security. But I agree, talking to younger people about these issue's, I'm convinced that the current fear of exposing sensitive data will decline within one or two generations, provided that structure and operations of health risk management does change in equal pace.
I think of it as the
facebook effect. David Brin has an excellent book on the topic
The_Transparent_Society. However,
Bruce Schneier has some excellent critisms of the work. I generally trust Schneier as one of the true authorities on all things security related, but we're all trying to read a crystal ball here.