47 replies to this topic

[brokenportal]

Come one, come all, give me your answers to this question, whether they be meager, or grand, I am taking them all. I convert them in to collaborations and avenues. You bring the plug and Ill plug it in. We've gotten many great ideas, mostly good right on ideas so far. Almost everything has been harnessed for the good. Almost every response has turned in to gain for the indefinite life extension cause. Keep them coming.

[binary888]

Educate people on fasting - fundamental principles - relation between digestion and elimination. http://www.mdsarequa...bestfriend.html
http://www.causeofdiseaseandaging.com/
Classic on aging and age reversal, little known book with profound
implications, Senescence & Revuvenescnece by C.M.Child, University of Chicago ~1914:
http://www.mdsarequa...ve00chil_bw.pdf

[scottknl]

To me it seems as if there's a progression from ignorance allows aging -> healthy lifestyle delays aging -> research for more methods to delay aging -> technology to impact aging.

I think the vast majority of people get stuck on the first stage, so in order to make the biggest impact on aging we should have at least one project that details the best/easiest methods to live a healthy lifestyle. Often there is such a large amount of info to cross-purposes, it becomes difficult to separate the wheat from the chaff. A beginner's forum with coarse organization and perhaps strict control on the simplicity of entries that focus on getting started on a healthy lifestyle might just be the ticket here. Perhaps just posting your "recipe" for healthy lifestyle would allow people to choose one to follow? Maybe even start with a recipe template? People could vote for their favorite recipe.

Cron-O-Meter is great at what it does, but it's not enough to track a healthy lifestyle. Open Source Software could be created to track exercise, medical test results/progress over time. I think gene testing could easily become another part of a healthy lifestyle in the near future and software like promethius could be folded into a one stop package to track a healthy lifestyle. If it was modular, then you could switch software modules in and out as things progress. Diet module, exercise module, med tests module, supplements module, gene profile module etc. Software is my specialty and I'd be happy to help or even generate a software architecture document and framework to use for this.

Funding is the major roadblock for the last 2 steps, so we should address this by getting people to sign up for an agreement to donate their worldly wealth to an aging research foundation in a will. Make it easier with last will and testament templates and maybe some kind of periodic reward system like a drawing for a prize from the people who have agreed.

[brokenportal]

Educate people on fasting - fundamental principles - relation between digestion and elimination. http://www.mdsarequa...bestfriend.html
http://www.causeofdiseaseandaging.com/
Classic on aging and age reversal, little known book with profound
implications, Senescence & Revuvenescnece by C.M.Child, University of Chicago ~1914:
http://www.mdsarequa...ve00chil_bw.pdf

Did you, or would you ever go to one of those fasting and CR camps? Educating people on fasting sounds like an alright idea to me, and probably like a great idea to a lot of people around here. Can you help add information in this section here as often as you can: http://www.longecity.../171-lifestyle/

If you have a more specific idea on how education might be spread on the topic then please do propose it here: http://www.longecity...orum/341-ideas/ and we move it to the next stage from there.

Also, please do consider adding your links to the Longecity links section: http://www.longecity.org/forum/links/

[brokenportal]

To me it seems as if there's a progression from ignorance allows aging -> healthy lifestyle delays aging -> research for more methods to delay aging -> technology to impact aging.

I think the vast majority of people get stuck on the first stage, so in order to make the biggest impact on aging we should have at least one project that details the best/easiest methods to live a healthy lifestyle. Often there is such a large amount of info to cross-purposes, it becomes difficult to separate the wheat from the chaff. A beginner's forum with coarse organization and perhaps strict control on the simplicity of entries that focus on getting started on a healthy lifestyle might just be the ticket here. Perhaps just posting your "recipe" for healthy lifestyle would allow people to choose one to follow? Maybe even start with a recipe template? People could vote for their favorite recipe.

Cron-O-Meter is great at what it does, but it's not enough to track a healthy lifestyle. Open Source Software could be created to track exercise, medical test results/progress over time. I think gene testing could easily become another part of a healthy lifestyle in the near future and software like promethius could be folded into a one stop package to track a healthy lifestyle. If it was modular, then you could switch software modules in and out as things progress. Diet module, exercise module, med tests module, supplements module, gene profile module etc. Software is my specialty and I'd be happy to help or even generate a software architecture document and framework to use for this.

Funding is the major roadblock for the last 2 steps, so we should address this by getting people to sign up for an agreement to donate their worldly wealth to an aging research foundation in a will. Make it easier with last will and testament templates and maybe some kind of periodic reward system like a drawing for a prize from the people who have agreed.

There are lots of recommended regimens, that is a good idea yes. We also put out a multi vitamin. A template might be useful, I would like to see it tried out. If you want to create one then please do. Im sure people will help you adjust it if need be from there. Could you come up with a list of key things that people should want to know about a complete lifestyle package? I think we could consider making a content management page that links to all the best most relevant topics from there then.

As for your software tracker idea, can you put a little more structure to that using the outline in this post here, and post it in that section? If there are parts you are unsure of, then fill them out the best you can, estimate, or skip them for now.

[revenant]

This may sound bizzare, but I am sure others have considered it. I believe there will be a time -maybe soon- when this will be possible. A small computer that can be worn on a person (or implanted) that will be able to sample blood intermittently for biomarkers, and then intravenously administer needed compounds in precise ammounts at precise times to attenuate aging. The insulin pump in use by diabetics makes me think this is very a reasonable consideration.

Edited by revenant, 11 September 2011 - 07:08 AM.

[brokenportal]

This may sound bizzare, but I am sure others have considered it. I believe there will be a time -maybe soon- when this will be possible. A small computer that can be worn on a person (or implanted) that will be able to sample blood intermittently for biomarkers, and then intravenously administer needed compounds in precise ammounts at precise times to attenuate aging. The insulin pump in use by diabetics makes me think this is very a reasonable consideration.

Can you find out who might be working on such a project already, or what company has the best means and ambitions to work on a project like that? If something like that is already underway then we might be able to make the case for helping with funding, exposure, etc. We would have to take it from there if you can gather such information.

[revenant]

I found a company called ALZET. I think they would have at least some of the expertise needed to develope a pump unit suitable for humans. http://www.alzet.com/

Here is an ALZET newsletter with some interesting info regarding anti-aging research and work with Geron http://freepdfhostin.../211efacb58.pdf



Something like this could be used without any need of a computer for sampling. This could be made available using technologies we have on hand today (the computerized pump could come later). Could the pumps be extant on the outside of the body rather than implanted; possibly using an IV catheter to deliver the goodies thus making replacement or refilling of the pumps simple? They would have to be replaced or refilled into containments that could be pressurized or remain pressurized to facililate osmosis. Such a deleviry method would be ideal for substances that are hydrolyzed or otherwise destroyed in the stomach such as catalase, SOD, curcuminoids, etc.

Edited by revenant, 21 November 2011 - 05:46 AM.

[Reformed-Redan]

I'd like a group of qualified people analyzing potential anti aging compounds in a manner consistent with such organizations as the FDA instead of waiting for 10 years for an approval.

At least, something of that sort.

[brokenportal]

I think you are talking about things like what Sierra Sciences does. They get batches of chemicals and test them for telomere growing properties I believe. Last I heard they were looking for funding to continue pouring through the thousands of compounds running the tests. I think that some synergy with Longecity here is possible. If that in particular appeals to you and you are interested in getting involved a bit then come up with a way that we could team up and outline it a bit here and we can go over it.

[ayu]

Putting my idea here RE: the newsletter that just went out.

I live in the San Francisco area where everyone (myself included) is really big into startups. The concept of the startup incubator or accelerator is pretty popular for effecting change in the world, simultaneously attracting money and talent. I think it'd be excellent if Longecity organized an accelerator/investment program that focuses on life extension work.
The most famous program is Y Combinator, but there's another one called Rock Health which is focused on tech and healthrelated companies.

Side note, this would probably require a lot of fund raising but I suspect many of Silicon Valley's newly minted millionaires would be more than willing to contribute. Affluent people are really fearful of death.

Edited by ayu, 10 April 2012 - 05:12 AM.

[brokenportal]

I found a company called ALZET. I think they would have at least some of the expertise needed to develope a pump unit suitable for humans. http://www.alzet.com/

Here is an ALZET newsletter with some interesting info regarding anti-aging research and work with Geron http://freepdfhostin.../211efacb58.pdf



Something like this could be used without any need of a computer for sampling. This could be made available using technologies we have on hand today (the computerized pump could come later). Could the pumps be extant on the outside of the body rather than implanted; possibly using an IV catheter to deliver the goodies thus making replacement or refilling of the pumps simple? They would have to be replaced or refilled into containments that could be pressurized or remain pressurized to facililate osmosis. Such a deleviry method would be ideal for substances that are hydrolyzed or otherwise destroyed in the stomach such as catalase, SOD, curcuminoids, etc.

Can you write to them and ask them if those sorts of pumps are use with humans too, what the restrictions might be, if patents have already been shot down, and things like that?

[brokenportal]

Putting my idea here RE: the newsletter that just went out.

I live in the San Francisco area where everyone (myself included) is really big into startups. The concept of the startup incubator or accelerator is pretty popular for effecting change in the world, simultaneously attracting money and talent. I think it'd be excellent if Longecity organized an accelerator/investment program that focuses on life extension work.
The most famous program is Y Combinator, but there's another one called Rock Health which is focused on tech and healthrelated companies.

Side note, this would probably require a lot of fund raising but I suspect many of Silicon Valley's newly minted millionaires would be more than willing to contribute. Affluent people are really fearful of death.

I like the concept. Have you started, invested or worked with a startup yourself?

Right now what we do is fund small research projects once or twice per year. Then there is a project about mid-sized between that and your idea here of an accelerator, a project like Petridish, and that is being discussed here. I encourage you to team up with that. Then also there is an indefinite life extension research accelerator run at MaxLife. MaxLife is set up for profit to investors. If we started one, hypothetically, it seems it would be best to run it with endowments.

We would need to bring people on board that know how to attract large dollars though. That is, unless we started a business side to Longecity and applied for an accelerator in order to start an indefinite life extension specific accelerator of our own. It sounds though, like we would be best off, again hypothetically here, to act as an agent to indefinite life extension startups that we vet for the cause, and then set up a system for helping them apply to other accelerators like Y Combinator, Rock Health, and MaxLife.

In the long run, if you or somebody else would see a project like this through, my recommendation would be to see what we can do to team up with MaxLife. Maybe help them promote their accelerator, vet for them, combine to fund some things with them - things like that.

As for affluent people and not wanting to die, I might have been inclined to think that way too, at one point. We talk to a lot of people though, affluent people particularly through our outreach project and in other places, and I dont get that impression through all of that. Can you give me the names of some affluent people you think might be fearful of death? I'll see if outreach volunteers will contact them.

Edited by brokenportal, 24 April 2012 - 01:31 AM.

[brokenportal]

I'd like a group of qualified people analyzing potential anti aging compounds in a manner consistent with such organizations as the FDA instead of waiting for 10 years for an approval.

At least, something of that sort.

Then also, can you look through this here and tell us how it may or may not relate to what you're talking about? I think they may do exactly what your talking about here: https://www.opencures.org/ They state it right on their front page. However maybe most to all places that fund science in this way do that. In that case then please do weigh in on this discussion here: http://www.longecity...er-curestarter/

From open cures:

• More than a dozen ways to extend life in mice have been demonstrated in laboratories
• Yet the US Food and Drug Administration (FDA) forbids commercial therapies for aging
• Thus the best biotechnologies for human longevity languish, undeveloped...
• But this is a shrinking world, linked by the internet and medical tourism
• Advanced, safe clinical development takes place in many countries
• We can work around the FDA, and this is how it will be done »

[Genises]

We all want to live longer but for me it will properly be to late to make a difference.
It will be the next generation who will benefit from any work done in substaining life.
Life begins for all whether you are Human or Animal with the first breath of air.
Followed by taking your first feed.
We all know the benefits of taking the first milk.
Why not take colostrum or colostrinin through out our life like we do with Milk.
I take it no long term study ie 10, 20 ,30 years has been done to verify the benefits long term.
I wonder why.Is it a product that would radify the requirements of taking pills.
First mothers milk has many benefits but we seem not to want to take research further when we as a world are spending hundreds of millions on finding a cure for many diseases.
Just may be we are staring at the solution to many problems from allergys,colds,flu,memory to actualy living longer.

What I like to see is more research projects done on colostrum and the peptides in colostrinin from colostrum.

[AgeVivo]

What is a project that you would like to see get going?


Mprize at home!
http://www.longecity...live-oil-study/
You can change the world.

Edited by AgeVivo, 21 August 2012 - 12:32 AM.

[Danail Bulgaria]

I definately would like to see a project, concerning the prevention of neurons death.

[IDoNotWantToDie]

What is a project that you would like to see get going, or get going more to help gain exposure for the indefinite healthy life extension cause?

Im sure you guys already got this project going ( if you do could you send me to the appropriate thread), but I was thinking of a project where people
interested in spreading the word of the Immortality Institute could set up a booth with Immortality Institute pamplets ,buttons, ect.
on college grounds or in front of their local grocery store or somewhere with a lot of traffic. I think it would be a good idea for people to take a short class, if they arent already
college students studying subjects related to immortality, on the Immortality Institute before being allowed to set up a booth so that they know what to say and how to answer peoples questions on the Immortality Institute.Maybe setting up a thread on what should be in the pamplets would be a start, that way people on this forum could just print the pamplets out and pass them out at
their college or to whoever. Pamplets are great because people could pass them out without even really knowing that much about the Institute, all they have to have is
is a passion for expanding human lifespan. Just make sure when people do print out the pamplets that they print them out on some good hard, glossy pamplet paper
because printing them out on cheap paper just seems unprofessional to me. Also maybe people could make buttons with the Immortality Institute logo
on them. And if people make booths the question ' Do you want to live forever? ' could be on the top in big letters and at the bottom you could have 'IMMORTALITY INSTITUTE'
in big bold letters with the logo on both sides. Im just spitballing here, as a group we could come up with better ideas and eventually decide whats best, but I think this will help spread the word
and get us closer to immortality or if not immortality perhaps at least living for a few thousand years instead of the measly 80 years we live to now, if we are lucky. Thats just not enough time for me,
I love life and have too much to do to live just 80 years or so.