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Digital Information Integrity vs DNA Deterioration


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#1 manofsan

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Posted 21 January 2004 - 12:03 AM


As our cells continue to duplicate across our lives, the quality of their genetic information deteriorates as errors accumulate. It reminds of the party game "broken telephone", whereby a message that is repeated again and again eventually becomes distorted. Or like making a photocopy of a photocopy of a photocopy, which will eventually become illegible.

Contrast this with the marvel of digital information technology, which allows us to make error-free copies of all sorts of files (bmp, mp3, mpg, avi, etc, etc) again and again, ad infinitum, avoiding loss of information.

How can this useful aspect of digital information technology be applied towards life-extension? Could we one day digitize our genomic information at birth, when its quality is at a more pristine/perfect state, and use that perfect copy to repair our genomic information when we are old and it has deteriorated?

Furthermore, even if we only have a flawed old-age sample of our DNA, couldn't we digitally "airbrush" this degraded DNA to generate a "youthful" version of the genome, with the flaws repaired?

The problem then is that once we have this "perfect" genome in digital format, we'd have to find a means to deploy it into our bodies, to make use of it. Somehow recombinant DNA technology doesn't seem like it would be adequate to implant an entire genome inside of us. So if the final hurdel of genome deployment were to be overcome, then it would pave the way for "digital re-mastering" of aged genomes.




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