40 replies to this topic

[cider]

http://www.prnewswir...l-85463852.html

It looks like there was an annoucement after all. But why "only one branded resveratrol pill has been proven to produce the pre-conditioning effect" ?

Howard Rothman, senior cardiologist at Advanced Cardiology Institute, warns resveratrol supplement users that the pre-conditioning effect of resveratrol is achieved at a dose ranging from 175-350 milligrams and higher doses may actually be counterproductive. Dr. Rothman says only one branded resveratrol pill has been proven to produce the pre-conditioning effect, which their group has recommended for over a year now.

That is Longevin**, right? Did they really compare with other brands? Anyone think this will gain traction in the public?

Edited by cider, 27 February 2010 - 01:29 AM.

[tunt01]

Do you have a reference for the homocysteine reduction?

id be curious on this too. i thought resveratrol slightly elevated homocysteine levels.

[cider]

Do you have a reference for the homocysteine reduction?

id be curious on this too. i thought resveratrol slightly elevated homocysteine levels.

No reference beyond that article.
Does anyone have the study where they base a dose recommendation at 175mg - 350mg for the possibility of heart protection?

[niner]

http://www.prnewswir...l-85463852.html

It looks like there was an annoucement after all. But why "only one branded resveratrol pill has been proven to produce the pre-conditioning effect" ?

Howard Rothman, senior cardiologist at Advanced Cardiology Institute, warns resveratrol supplement users that the pre-conditioning effect of resveratrol is achieved at a dose ranging from 175-350 milligrams and higher doses may actually be counterproductive. Dr. Rothman says only one branded resveratrol pill has been proven to produce the pre-conditioning effect, which their group has recommended for over a year now.

That is Longevin**, right? Did they really compare with other brands? Anyone think this will gain traction in the public?

Well of course that's what it was. This announcement wasn't from the NIH, it was a paid PRNewswire from your buddy Bill "rez-vair-ah-trawl" Sardi.

[eason]

I sure hope these cardiologists wouldn't risk their reputations to give their patients with heart disease resveratrol just to promote Longevinex. Sure, they used it, but that doesn't necessarily mean the end result is invalid.

[eason]

I do have a feeling that this entire thread was set up by Bill Sardi, though. Guess we'll have to wait for the monkey results later.

[cider]

Well of course that's what it was. This announcement wasn't from the NIH, it was a paid PRNewswire from your buddy Bill "rez-vair-ah-trawl" Sardi.

I was wondering about that. I started the thread because Sardi announced a week or two ago on a doctor's health podcast that there was going to be a big announcement Feb 25th at the NIH. It looks like there was some presentation there, though.

Uncle Bill... I mean... Mr. Sardi's own press release looked like half interesting info, half advertisement, but the PRNewswire looks like it could be an ad, yet I don't see where except at the end as it claims only one brand was effective. That didn't seem right.

So what parts of the article hold up? Is the Advanced Cardiology Institute some kind of front? They look like such nice people in their pic... They have a map, so they must be legit.

How does this work? The article starts:
"In a presentation at a National Institutes of Health symposium in Washington DC today, University of Connecticut researchers showed resveratrol limits damage caused by a heart attack, prevents sudden cardiac death in animals, and is "the best yet devised method of cardioprotection." (The italyics make it seem like an ad)

But that actually took place, right?

Yet this statement on dosage...
"Howard Rothman, senior cardiologist at Advanced Cardiology Institute, warns resveratrol supplement users that the pre-conditioning effect of resveratrol is achieved at a dose ranging from 175-350 milligrams and higher doses may actually be counterproductive. "

... is just Rothman's opinion, or is it a recommendation based on Das' work.

At any rate, do you buy the 175-350mg range?

Edited by cider, 27 February 2010 - 07:06 AM.

[niner]

There was never going to be an announcement from the "NIH", was there?

A friend emailed it. He just added that he heard it from a guy at a gym who said he heard it on a health podcast. More indirect than I thought. He was specific though: NIH announcement Feb 25th on resveratrol and the heart. Maybe they completed a study or are announcing a survey of studies. No idea.

Holmes, your nose is growing... Feb 25 was the timing for Sardi's PR blitz. This is all based on Das' work. I can't find any published evidence that Das actually used L*ng*v*n*x though.

[eason]

At any rate, do you buy the 175-350mg range?

The 175-350 range was extrapolated from a 2007 University of Connecticut study conducted in mice.

[cider]

At any rate, do you buy the 175-350mg range?

The 175-350 range was extrapolated from a 2007 University of Connecticut study conducted in mice.

That's what I thought... Assuming there was a presentation at the NIH, was there anything new? That study is now two years old.
That range comes close to Sinclair's recommendation of staying under 250mg, yet he himself said he was at 320mg for years.
And that was based on weight, so the 175-350mg recommendation based on the U of Conn study and Sinclair under 250mg statement are a little strange since not weight based.

Edited by cider, 27 February 2010 - 07:30 AM.

[maxwatt]

Cider aka Holmes stepped over the line with name-calling in a post I've deleted as a Navigator. I've suspended him for a few days. However this thread seems to have been intended only to call attention to Bull Sordi's press release. There were really no new research findings. Discussing the implications of older findings is legitimate, but that was not possible given the lackof citations and the repetitive rhetorical nature of cider/Holmes' reflexive posting. I have started a new topic on homocysteine that originated here, maybe we could get some insights into this phenomena.

I also renamed the topic; the original had a spelling error, and I've fixed that by more accurately describing this thread's content.

Edited by maxwatt, 27 February 2010 - 02:09 PM.