41 replies to this topic

[browser]

So you're still taking resveratrol, but now you're asymptomatic. Hmm. One of the major things that changed in your regimen is quercetin. Maybe quercetin (or some other component of the original regimen) is the problem.

Perhaps the Quercetin. But I'm thinking more that Resveratrol promotes longevity of cells up to a certain dosage. Above that dose it promotes apoptosis. This is why I maxed out on the amount of Resveratrol I'm takng. I don't like the idea of taking sodium ascorbate and Vitamin E but I need something to protect the Curcumin. Note that I'm not promoting R+C. Until I get my blood work back, I could just be enjoying anti-inflammatory action.

Resveratrol is an aromatase inhibitor and also suppresses aromatase expression. While it's not particularly potent, the activity is seen in vitro at concentrations that are not wildly different than pharmacological concentrations. Aromatase inhibition has been shown to increase testosterone significantly in older men. There has been at least one report here of increased libido in males taking resveratrol. This is at least a plausible mechanism for resveratrol to bump up PSA in an androgen sensitive cancer.

[a couple abstracts]

Interesting, except that I'm taking DIM and chrysin in a bio-identical cream prescribed by my doctor. I also supplement with Testosterone. The other men I spoke of also take DIM and chrysin, some take prescription aromatase inhibitors and have their Testosterone, Estrogen(s) and DHT checked regularly. Some take supplemental Testosterone. They did not notice a change in T, Es or DHT. My doctor and many others with prostate cancer patients these days are very sensitive to the T:E2 ratio, test for it often and prescribe natural or prescription aromatase inhibitors freely.

Well this is interesting indeed. Are you saying that supplemental T isn't promoting tumor growth or bumping up PSA? Conventional wisdom (which may well be wrong) would have you doing the opposite. I remember you saying that the point was to not develop an androgen-insensitive tumor, which would presumably be worse than an androgen-sensitive one. There are a lot of guys who would like to supplement T but are afraid of promoting growth of indolent cancer cells that a lot of (most?) older men have. Is your experience here evidence that this fear is unwarranted, or are you accepting a certain amount of cancer promotion from the T in order to avoid a worse form of cancer?

I want to point out that Testosterone has a U curve relationship with prostate cancer growth. Low T (which means of course low Estradiol) inhibits cancer growth and will even make prostate cancer dormant as long as it are not androgen dependent. High doses of T (which probably implies a decent T:E2 ratio) has been used in advanced cases of prostate cancer to kill off the PCa. There are studies on Estradiol and studies on Testosterone and I remember a PubMed abstract of 2007 which I can no longer find in which both T and E2 were measured. One has to draw one's own conclusion when reading the studies on T and E2 and prostate cancer what the ratio between them what have been. A study design flaw repeated over and over again, alas.

[mikeinnaples]

Now Anthony Loera, in the style of "But Brutus is an honorable man" keeps ragging on my taking 12 capsules of Nitro 250 and 12 capsules of MCT Quercetin, implying that I did something terribly wrong, my doctor is a incompetent, or I'm not getting my doctor's approval. The fact is, Dr. Myers thought that 2 capsules of Longevinex plus 2 capsules of Quercetin was good for prostate cancer patients. He thought that 2-4 capsules each of Nitro 250 and MCT Quercetin were good for prostate cancer patients. So if 4 capsules each were good for prostate cancer, then it naturally follows that 12 capsules each are bad for prostate cancer?

To be completely honest with you ...12 caps of both a day is an absolutely insane amount given the increased bioavailability. I think if you up a dose way above what a doctor recommends, it can possbily be an issue. Case in point, 800mg of Ibuprofen is very beneficial, but 4 grams of the stuff all at once and I would have kidney failure most likely.

[browser]

Now Anthony Loera, in the style of "But Brutus is an honorable man" keeps ragging on my taking 12 capsules of Nitro 250 and 12 capsules of MCT Quercetin, implying that I did something terribly wrong, my doctor is a incompetent, or I'm not getting my doctor's approval. The fact is, Dr. Myers thought that 2 capsules of Longevinex plus 2 capsules of Quercetin was good for prostate cancer patients. He thought that 2-4 capsules each of Nitro 250 and MCT Quercetin were good for prostate cancer patients. So if 4 capsules each were good for prostate cancer, then it naturally follows that 12 capsules each are bad for prostate cancer?

To be completely honest with you ...12 caps of both a day is an absolutely insane amount given the increased bioavailability. I think if you up a dose way above what a doctor recommends, it can possbily be an issue. Case in point, 800mg of Ibuprofen is very beneficial, but 4 grams of the stuff all at once and I would have kidney failure most likely.

Thanks for your misplaced concern. Resveratrol has been shown in humans to be safer at much high doses than I was taking when downing 3 grams of Nitro 250 and MCT Quercetin, though Anthony Loera is trying to make me out to be some kind of deranged criminal because I was taking 12 of his Nitro 250 and 12 of his MCT Quercetin. Now as far as your concern about the extra bioavailability or absorption of Revgenetics' products. This is something that remains to be proved. Revgenetics has sponsored no studies that I am aware of showing that its knockoff of Bill Sinclair's patented formulations (and we know how reliable patents are) is as bioavailable and has the same alleged absorption as Sinclair showed in his patent. Bill Sinclair's patent doesn't mention increased bioavailability or absorption of Quercetin by mixing it into MCT.

With respect to your concern and Anthony Loera's misplaced defensive concern about me overdosing on 3 grams of Resveratrol and 3 grams of Quercetin, I'm trying to kill prostate cancer here. Resveratrol and Quercetin aren't in the same toxic league as ibuprofen. What I'm doing is suggested and borne out by research invitro and invivo.

[bixbyte]

This is a repost. The first post of this topic disappeared about 10 minutes after being posted.


My PSA rose 28% during the period I took

- 8 Longevinex (4 weeks)
- 8 Longevinex + 8 grams Quercetin (4 weeks)
- 4 Nitro 250 + 4 MCT Quercetin + 8 grams Quercetin during the rest of the day (4 weeks)
- 12 Nitro 250 + 12 MCT Quercetin + 8 grams Quercetin during the rest fo the day (4 weeks)

My PSA and been gradually dropping and my symptoms had been abating on the twice weekly 75 grams Vitamin C IV and 500 mg. per kg. IP6+Inositol without any of the above.

Other prostate cancer patients, who have already been treated with surgery, radiation and ADT and not on chemo (which Vitamin C IVs can be considered) have told me that they noticed that their PSA rose while taking the 2 Nitro 250s + 2 MCT Quercetins Dr. Snuffy Myers, the noted Prostate Cancer oncologist recommends. These patients have stopped taking Resveratrol. My doctor reported the negative results of taking Resveratrol + Quercetin with prostate cancer to Dr. Myers

I am now asymptomatic as I've not been in 10 years since I began taking for the past 3 weeks:

2 adult aspirins with a glass of grapefruit juice upon arising

20-30 minutes later an emulsion containing

- 1/4 cup coconut oil
- 20 mg. Bioperine
- 20 grams Resveratrol (from Vitaspace)
- 12.5 grams Curcumin (from Vitamspace)
- 1.25 grams sodium ascorbate
- 1,000 IU Vitamin E

The above is blended in a powerful, high speed blender for an hour the night before than blended the next morning with a glass of grapefruit juice for 20-30 minutes, hopefully micronizing and suspending the paste created the night before. The drink is tolerable but there are very disruptive GI disturbances for about 6 hours after downing it. I also stuff Resveratrol (from Vitaspace) between my gums and cheeks from arising to Noon. I'm awaiting 20 mg. Resveratrol lozenges. When they arrive, I'll switch to the lozenges for buccal and sublingual delivery.

It's possible I'm just symptom free because Resveratrol is an anti-inflamatory. I have used special toothpaste for sensitive teeth for years. I recently stopped using the toothpaste and only use an electric toothbrush. When I've done this in the past, my teeth became painfully sensitive to hot and cold. That has not happened this time. I suspect the Resveratrol in my mouth all morning has something to do with this. If my symptoms have gone away from anti-inflammatory effects of the Resveratrol, then why did my symptoms get worse before going to the very high dose of Resveratrol? Curcumin is also an anti-inflammatory. I'll have more of an indication of what's really happening when I get extensive blood work at the end of the month. It's too early for another PSA test but perhaps my doctor and I will get an idea which direction my prostate cancer growth is going.

I offered you my humble opinion that you ask your MD to allow you to try Propecia 1 mg daily dose.
Sounds like your MD is using some rational that hormone balance between Testosterone and Estrogen will prevent Prostate Cancer proliferation.
But you are not a 21 year old with BRCA or BRCB genotype.
How about asking your Doctor for Proton Radiation therapy?
Non-Invasive, no surgery involved, usually little or no side effects after Proton Radiation.
There are only a couple centers in the USA that have a cyclotron to launch protons directly to the prostate.
This procedure is covered by Medicare.
Protons have a short life they change to nothing when they hit a piece of paper.
But the fancy part of this procedure comes in if we use a nuclear accelerator and direct the proton particle beam directly on the prostate.
There is no radiation spread since the protons turn to nothing in micro seconds after irradiating only the prostate.
That leaves usually no side effects from this procedure. Maybe a little soreness taking a pee for a couple days at worst.
Plus a high success rate of "cooking" the prostate but none of the side effects like surgery, robot knife, conventional radiation.

I am telling you this, because I know a little bit about prostate cancer.
There is no regular treatment as it is up to you the patient with PC to decide.
Sounds like watchful waiting is not working out for you.
As you are aware most men have prostate cancer but we die from something else.
Proton Radiation is the safe and effective.
Good Luck!

[mikeinnaples]

Now Anthony Loera, in the style of "But Brutus is an honorable man" keeps ragging on my taking 12 capsules of Nitro 250 and 12 capsules of MCT Quercetin, implying that I did something terribly wrong, my doctor is a incompetent, or I'm not getting my doctor's approval. The fact is, Dr. Myers thought that 2 capsules of Longevinex plus 2 capsules of Quercetin was good for prostate cancer patients. He thought that 2-4 capsules each of Nitro 250 and MCT Quercetin were good for prostate cancer patients. So if 4 capsules each were good for prostate cancer, then it naturally follows that 12 capsules each are bad for prostate cancer?

To be completely honest with you ...12 caps of both a day is an absolutely insane amount given the increased bioavailability. I think if you up a dose way above what a doctor recommends, it can possbily be an issue. Case in point, 800mg of Ibuprofen is very beneficial, but 4 grams of the stuff all at once and I would have kidney failure most likely.

Thanks for your misplaced concern. Resveratrol has been shown in humans to be safer at much high doses than I was taking when downing 3 grams of Nitro 250 and MCT Quercetin, though Anthony Loera is trying to make me out to be some kind of deranged criminal because I was taking 12 of his Nitro 250 and 12 of his MCT Quercetin. Now as far as your concern about the extra bioavailability or absorption of Revgenetics' products. This is something that remains to be proved. Revgenetics has sponsored no studies that I am aware of showing that its knockoff of Bill Sinclair's patented formulations (and we know how reliable patents are) is as bioavailable and has the same alleged absorption as Sinclair showed in his patent. Bill Sinclair's patent doesn't mention increased bioavailability or absorption of Quercetin by mixing it into MCT.

With respect to your concern and Anthony Loera's misplaced defensive concern about me overdosing on 3 grams of Resveratrol and 3 grams of Quercetin, I'm trying to kill prostate cancer here. Resveratrol and Quercetin aren't in the same toxic league as ibuprofen. What I'm doing is suggested and borne out by research invitro and invivo.

You need to settle down man. Nobody is treating you like a deranged criminal. I understand you are upset about your PSA, but you need to take a step back, take a deep breath, and calm down a little so you can approach this with a cool head instead of coming across like a raving lunatic.

Now with that said, there is independant data on greatly increased levels of Resv in the system with Tween/MCT/Lethecin. This is independant of any supplier. Do a few searches within these forums. Your logic and reasoning behind making the assumption that more product = more effect is illogical and illadvised especially given the fact that you are taking way above and beyond what the doctor told you to take, a doctor that is not only an expert, but progressive and up to date with the latest/greatest research. Some times more = much less or more = harmful and there is absolutely no concrete research in humans at the plasma levels you were most likely obtaining with that much Nitro 250. Sure you can say you 'are only taking 3 grams', but if you understand the increased absorption of micronized resv in MCT, Tween, or even Lecethin -AND- combine it with the synergy from quercetin, you are charting grossly into unknown territory.

By the way ...who is Bill Sinclair?

Edited by mikeinnaples, 15 April 2010 - 11:58 AM.

[Logan]

By the way ...who is Bill Sinclair?

Combine Bill Sardi with David Sinclair and you get Bill Sinclair.

[browser]

So you're still taking resveratrol, but now you're asymptomatic. Hmm. One of the major things that changed in your regimen is quercetin. Maybe quercetin (or some other component of the original regimen) is the problem.

Perhaps the Quercetin. But I'm thinking more that Resveratrol promotes longevity of cells up to a certain dosage. Above that dose it promotes apoptosis. This is why I maxed out on the amount of Resveratrol I'm takng. I don't like the idea of taking sodium ascorbate and Vitamin E but I need something to protect the Curcumin. Note that I'm not promoting R+C. Until I get my blood work back, I could just be enjoying anti-inflammatory action.

Resveratrol is an aromatase inhibitor and also suppresses aromatase expression. While it's not particularly potent, the activity is seen in vitro at concentrations that are not wildly different than pharmacological concentrations. Aromatase inhibition has been shown to increase testosterone significantly in older men. There has been at least one report here of increased libido in males taking resveratrol. This is at least a plausible mechanism for resveratrol to bump up PSA in an androgen sensitive cancer.

[a couple abstracts]

Interesting, except that I'm taking DIM and chrysin in a bio-identical cream prescribed by my doctor. I also supplement with Testosterone. The other men I spoke of also take DIM and chrysin, some take prescription aromatase inhibitors and have their Testosterone, Estrogen(s) and DHT checked regularly. Some take supplemental Testosterone. They did not notice a change in T, Es or DHT. My doctor and many others with prostate cancer patients these days are very sensitive to the T:E2 ratio, test for it often and prescribe natural or prescription aromatase inhibitors freely.

Well this is interesting indeed. Are you saying that supplemental T isn't promoting tumor growth or bumping up PSA? Conventional wisdom (which may well be wrong) would have you doing the opposite. I remember you saying that the point was to not develop an androgen-insensitive tumor, which would presumably be worse than an androgen-sensitive one. There are a lot of guys who would like to supplement T but are afraid of promoting growth of indolent cancer cells that a lot of (most?) older men have. Is your experience here evidence that this fear is unwarranted, or are you accepting a certain amount of cancer promotion from the T in order to avoid a worse form of cancer?

J Sex Med. 2010 Apr;7(4 Pt 2):1627-56.
Endocrine aspects of male sexual dysfunctions.

Buvat J, Maggi M, Gooren L, Guay AT, Kaufman J, Morgentaler A, Schulman C, Tan HM, Torres LO, Yassin A, Zitzmann M.

Centre d'Etudes et de Traitement de la Pathologie de l'Appareil Reproducteur et de la Psychosomatique, Lille, France. jacques@buvat.org
Abstract

INTRODUCTION: Endocrine disorders may adversely affect men's sexual function. AIM: To provide recommendations based on best evidence for diagnosis and treatment of endocrine-related male sexual dysfunctions. METHODS: The Endocrine Aspects of Male Sexual Dysfunctions Committee, including 11 members from eight countries and four continents, collaborated with the Endocrine subcommittee of the Standards Committee of the International Society for Sexual Medicine. Medical literature was reviewed in detail, followed by extensive internal committee discussion over 2 years, then public presentation and discussion with the other experts before finalizing the report. MAIN OUTCOME MEASURE: Recommendations based on grading of evidence-base medical literature and interactive discussion. RESULTS: From animal studies, it is derived that testosterone modulates mechanisms involved in erectile machinery, including expression of enzymes that both initiate and terminate erection. In addition, testosterone is essential for sexual motivation. Whether these findings could be extrapolated to human erections is unclear. Testosterone plays a broad role in men's overall health. Recent studies have established strong associations between low testosterone and metabolic and cardiovascular imbalances. In some studies, low testosterone decreased longevity; however, longitudinal studies do not support the predictive value of low testosterone for further cardiovascular events. The article proposes a standardized process for diagnosis and treatment of endocrine-related male sexual dysfunctions, updating the knowledge on testosterone and prostate safety. There is no compelling evidence that testosterone treatment causes prostate cancer or its progression in men without severe testosterone deficiency (TD). The possible roles of prolactin and thyroid hormones are also examined. CONCLUSIONS: Men with erectile dysfunction, hypoactive sexual desire and retarded ejaculation, as well as those with visceral obesity and metabolic diseases, should be screened for TD and treated. Prospective interventional studies are required before screening for TD in more conditions, including cardiovascular diseases, and considering correction as preventive medicine as much data suggests.

[fatboy]

...my bio-identical cream (one property of which is to prevent formation of Estradiol and DHT), ...

Interesting, except that I'm taking DIM and chrysin in a bio-identical cream prescribed by my doctor.

I've been on Androgel 10g/day for a couple of years now. (Best thing to ever happen to me was the fellas finally giving up the ghost. I feel like I'm 47 yo going on 18.) The DIM and chrysin will inhibit aromatase and conversion to E2 but what's in your cream to inhibit 5-ar conversion to DHT?

I started the 100 mg. pure T sublingual twice a day ...

Do you happen to know the average absorption rate of your sublingual? Is it Big Pharma or compunded? Typical TRT doses are in the range of 70-150 mgs/week of T. Androgel's average absorption rate is about 10% in a 1% concentration so my dose yields an average of about 70mg/week.

Men with prostate cancer (usually already nuked prostate cancer) are concerned about their T:E2 ratio. That's what my doctor's concerned about.

More and more Doctors are starting to agree with this. My TRT is administered by my PCP (not an endocrinologist) and this is also what he believes important.

Good Luck!

[browser]

I'm interested in agonizing the P53 gene so because of this and for the sake of my digestion, I'm going to mix an emulsion tonight without the Curcumin and the Vitamin E and sodium ascorbate. The two aspirins, the Bioperine and grapefruit juice ought to be enough help prevent first pass metabolism of the Resveratrol, though the high dose alone (20 grams) should be enough to swamp any CYP action against it. And no, Anthony, though I'm going to go get a Vitamin C IV from my doctor today, I'm not going to get a prescription from him to drop the Curcumin and the anti-oxidants to protect it from my list of supplements.

FYI

http://anti-agingfir...nt-in-the-news/

FYI

http://www.ncbi.nlm....pubmed/20395211

Cancer Res. 2010 Apr 15;70(8):3382-90.

<h1 style="font-size: 1.3333em; line-height: 1.125em; font-weight: bold; margin: 0.375em 0px;">Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.</h1>Slusarz A, Shenouda NS, Sakla MS, Drenkhahn SK, Narula AS, MacDonald RS, Besch-Williford CL, Lubahn DB.

Department of Biochemistry, University of Missouri, Columbia, Missouri 65211, USA.

<h3 style="font-size: 1em; color: rgb(152, 87, 53); font-weight: bold; margin: 0px;">Abstract</h3>Many botanical compounds have been proposed to prevent cancer. We investigated the cancer treatment and prevention abilities of apigenin, baicalein, curcumin, epigallocatechin 3-gallate (EGCG), genistein, quercetin, and resveratrol both in vivo in transgenic adenocarcinoma of the mouse prostate (TRAMP) mice as well as in vitro in prostate cancer cell lines. In our experiments, these seven compounds act similarly to the Hedgehog antagonist cyclopamine, a teratogenic plant alkaloid, which had been previously shown to "cure" prostate cancer in a mouse xenograft model. With IC(50) values ranging from <1 to 25 mumol/L, these compounds can inhibit Gli1 mRNA concentration by up to 95% and downregulate Gli reporter activity by 80%. We show that four compounds, genistein, curcumin, EGCG, and resveratrol, inhibit Hedgehog signaling as monitored by real-time reverse transcription-PCR analysis of Gli1 mRNA concentration or by Gli reporter activity. Three compounds, apigenin, baicalein, and quercetin, decreased Gli1 mRNA concentration but not Gli reporter activity. Our results show that these compounds are also able to reduce or delay prostate cancer in vivo in TRAMP mice. All seven compounds, when fed in combination as pure compounds or as crude plant extracts, inhibit well-differentiated carcinoma of the prostate by 58% and 81%, respectively. In vitro, we show that all seven compounds also inhibit growth in human and mouse prostate cancer cell lines. Mechanistically, we propose the Hedgehog signaling pathway to be a direct or indirect target of these compounds. These botanicals at pharmacologic concentrations are potentially safer and less expensive alternatives to cyclopamine and its pharmaceutical analogues for cancer therapy. © 2010 AACR.

PMID: 20395211 [PubMed - in process]

[Hedrock]

The combination of Resveratrol + Honokiol seems very promising to me. In my own theory they could (maybe) act synergistic.

This combination is not tested yet, but the single action of honokiol is very impressive. Another advantage is Honokiol does not inhibit the T-cells (other substances often suppress immune system).

Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function.

Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction

Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity.

Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo*

The last article has very impressive pictures and diagrams. You should read it.

Edited by Hedrock, 04 May 2010 - 10:31 PM.

[browser]

This is a repost. The first post of this topic disappeared about 10 minutes after being posted.


My PSA rose 28% during the period I took

- 8 Longevinex (4 weeks)
- 8 Longevinex + 8 grams Quercetin (4 weeks)
- 4 Nitro 250 + 4 MCT Quercetin + 8 grams Quercetin during the rest of the day (4 weeks)
- 12 Nitro 250 + 12 MCT Quercetin + 8 grams Quercetin during the rest fo the day (4 weeks)

My PSA and been gradually dropping and my symptoms had been abating on the twice weekly 75 grams Vitamin C IV and 500 mg. per kg. IP6+Inositol without any of the above.

Other prostate cancer patients, who have already been treated with surgery, radiation and ADT and not on chemo (which Vitamin C IVs can be considered) have told me that they noticed that their PSA rose while taking the 2 Nitro 250s + 2 MCT Quercetins Dr. Snuffy Myers, the noted Prostate Cancer oncologist recommends. These patients have stopped taking Resveratrol. My doctor reported the negative results of taking Resveratrol + Quercetin with prostate cancer to Dr. Myers

I am now asymptomatic as I've not been in 10 years since I began taking for the past 3 weeks:

2 adult aspirins with a glass of grapefruit juice upon arising

20-30 minutes later an emulsion containing

- 1/4 cup coconut oil
- 20 mg. Bioperine
- 20 grams Resveratrol (from Vitaspace)
- 12.5 grams Curcumin (from Vitamspace)
- 1.25 grams sodium ascorbate
- 1,000 IU Vitamin E

The above is blended in a powerful, high speed blender for an hour the night before than blended the next morning with a glass of grapefruit juice for 20-30 minutes, hopefully micronizing and suspending the paste created the night before. The drink is tolerable but there are very disruptive GI disturbances for about 6 hours after downing it. I also stuff Resveratrol (from Vitaspace) between my gums and cheeks from arising to Noon. I'm awaiting 20 mg. Resveratrol lozenges. When they arrive, I'll switch to the lozenges for buccal and sublingual delivery.

It's possible I'm just symptom free because Resveratrol is an anti-inflamatory. I have used special toothpaste for sensitive teeth for years. I recently stopped using the toothpaste and only use an electric toothbrush. When I've done this in the past, my teeth became painfully sensitive to hot and cold. That has not happened this time. I suspect the Resveratrol in my mouth all morning has something to do with this. If my symptoms have gone away from anti-inflammatory effects of the Resveratrol, then why did my symptoms get worse before going to the very high dose of Resveratrol? Curcumin is also an anti-inflammatory. I'll have more of an indication of what's really happening when I get extensive blood work at the end of the month. It's too early for another PSA test but perhaps my doctor and I will get an idea which direction my prostate cancer growth is going.

I need someone with the power to change the title of the topic. Resveratol + Quercetin may promote Prostate Cancer. Or it might not.

I was preparing for the results of my latest blood draw and came upon a slew of cites like This on page 347 where it's stated that
"if you give Taxotere
and measure PSA several days later, you will have
an increase in PSA because of tumor dying out and
releasing PSA."

"There is a 'syndrome' whereby prostate cancer patients treated with radiation exhibit what is referred to as a 'bounce effect.' Essentially, many months (sometimes years) after radiation therapy, a bounce or rise in PSA levels are experienced. This is recognized as normal and studies show it does not effect long term survivability. My experience with radiation is that it does, indeed, often take many months to produce a death effect on cancer cells. A Google search of "PSA bounce" produces many hits to that effect."

"For men with prostate cancer, a rise in PSA levels after radiation therapy -- called PSA bounce -- is not clinically relevant and doesn't affect survival, researchers from Fox Chase Cancer Center report."

[niner]

I need someone with the power to change the title of the topic. Resveratol + Quercetin may promote Prostate Cancer. Or it might not.

Will do.