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[M-Blog] The End to Tooth Decay?


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#1 ImmInst

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Posted 13 December 2010 - 06:09 PM


The health of your mouth mirrors the condition of your body’s health as a whole. Research shows that more than 90 percent of all systemic diseases (involving many organs or the whole body) manifest themselves orally: swollen gums, mouth ulcers, dry mouth and/or excessive gum problems. Such systemic diseases include diabetes, cancer, heart disease, kidney disease, and leukemia. Bottom line: great oral care equates to better health.

But what if you could brush your teeth with toothpaste that ensures that cavities will be a thing of the past? What if you could eat candy with a property that prevents plaque from forming on the surfaces of your pearly whites?

Armed with knowledge of the structure and mechanism of the enzyme responsible for the plaque that cakes your teeth, professors Bauke Dijkstra and Lubbert Dijkhuizen from The Groningen University can push forward to identify the substance that inhibits the enzyme glucansucrase. The bacterium Streptococcus mutans uses glucansucrase to attach itself to the tooth enamel, ferment sugar-releasing acids that in turn dissolve the calcium in teeth. This is how cavities occur and why this bacterium is the main cause of tooth decay.

Read more about the structure, mechanism, and evolution of glucansucrase:
http://www.scienceda...01203101341.htm




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#2 robomoon

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Posted 13 December 2010 - 09:31 PM

This must get ready for implementation into a highly profitable nano-toothpaste. The superior oral drug for extra costly and special scientific prescription procedures performed by professional dentists. So any pharmacy store and dentist can make a great profit with it, not from a hole in the tooth, but from the prevention of such. Without greater profits for anyone, developers of an exclusive glucansucrase inhibitor will only bite on granite.

Edited by robomoon, 13 December 2010 - 09:42 PM.


#3 Mind

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Posted 12 February 2012 - 03:58 PM

Another method of fighting tooth decay:

http://www.scienceda...11116045657.htm

In a recent clinical study, 12 subjects who rinsed just one time with the experimental mouthwash experienced a nearly complete elimination of the

S. mutans

bacteria over the entire four-day testing period. The findings from the small-scale study are published in the current edition of the international dental journal

Caries Research

.


Dental caries, commonly known as tooth decay or cavities, is one of the most common and costly infectious diseases in the United States, affecting more than 50 percent of children and the vast majority of adults aged 18 and older. Americans spend more than $70 billion each year on dental services, with the majority of that amount going toward the treatment of dental caries.



#4 Danail Bulgaria

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Posted 12 February 2012 - 06:20 PM

The idea to kill Streptococcus mutans is everything but new. So far many things are tried - antibiotics, vacines, mouthwashes, tablets dissolving in the mouth and whatevery You may think of. And each time in the researches appears a very promissing compound, and every time the compound gets busted. One of the reasons for that, that are supposed to is the fact, that Streptococcus mutans is very adaptive and variable.
However, the practice showed, that there are effective way for prevention and an effective way of treatment of the tooth decay. These, everybody knows of, are the correct brushing of the teeth(profilaxy), and the treatment is the mechanical removal of the carious tissue, and replacing the removed hard tissues with artifitial materials.




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