46 replies to this topic

[maxwatt]

there are a number of animal studies looking at blood lipids and resveratrol. Bix is his own lab rat.

[scottknl]

Duke really has a habit of jumping all over anyone who has an improved lipid profile and suggesting that they're not really all that healthy.

I say nice improvements, Bix. Keep up the good habits.

Edited by scottknl, 16 December 2011 - 06:25 AM.

[DukeNukem]

HDL may be low by Duke's strict standards, but total cholesterol is also low, so as a percentage HDL is higher than the absolute number says, In that HDL is an indirect measure of scavenging activity of fat from artery walls, what this means would depend on what deposits if any there are to scavenge.

Triglycerides are well within normal range by standard reference, but again by Duke's standards are too high. Much would depend on the size and nature of the particles, whether they convert to low density cholesterol, the presence and number of foam cells that deposit lipids in arteries. etc.

The size of the VLDL cholesterol particles is a data point I would want to see. If it is relatively large, I'd say Bix probably has little to worry about. Otherwise, it's hard to say except that by the measure of conventional medical wisdom, the numbers are good.

When HDL is low and trigs are 100+, that's a guarantee that the LDL breakdown includes too much VLDL.

[maxwatt]

HDL may be low by Duke's strict standards, but total cholesterol is also low, so as a percentage HDL is higher than the absolute number says, In that HDL is an indirect measure of scavenging activity of fat from artery walls, what this means would depend on what deposits if any there are to scavenge.

Triglycerides are well within normal range by standard reference, but again by Duke's standards are too high. Much would depend on the size and nature of the particles, whether they convert to low density cholesterol, the presence and number of foam cells that deposit lipids in arteries. etc.

The size of the VLDL cholesterol particles is a data point I would want to see. If it is relatively large, I'd say Bix probably has little to worry about. Otherwise, it's hard to say except that by the measure of conventional medical wisdom, the numbers are good.

When HDL is low and trigs are 100+, that's a guarantee that the LDL breakdown includes too much VLDL.

bixbyte's trilycerides were 60, I assume that means he does not have too much VLDL.

[scottknl]

HDL may be low by Duke's strict standards, but total cholesterol is also low, so as a percentage HDL is higher than the absolute number says, In that HDL is an indirect measure of scavenging activity of fat from artery walls, what this means would depend on what deposits if any there are to scavenge.

Triglycerides are well within normal range by standard reference, but again by Duke's standards are too high. Much would depend on the size and nature of the particles, whether they convert to low density cholesterol, the presence and number of foam cells that deposit lipids in arteries. etc.

The size of the VLDL cholesterol particles is a data point I would want to see. If it is relatively large, I'd say Bix probably has little to worry about. Otherwise, it's hard to say except that by the measure of conventional medical wisdom, the numbers are good.

When HDL is low and trigs are 100+, that's a guarantee that the LDL breakdown includes too much VLDL.

bixbyte's trilycerides were 60, I assume that means he does not have too much VLDL.

The 60 reading was from his wife's report (her numbers are pretty good). His trigs were a higher at 131, not too crazy high, but could be better. His HDL was low at 35. Low HDL and high trigs are a sign bixbyte is eating too many carbohydrates in his diet. The fix is usually to up the intake of healthy dietary fats with good ratio of Omega-6 and Omega-3 fatty acids while lowering consumption of simple carbohydrates. It seems to work in most people who don't have genetic familial high cholesterol.

My experience was similar, to bixbyte's but I also did CRON at the same time. The result was that my numbers were worse than bixbyes at the start and now similar to his wife's. My personal proof of athletic ability is that my 1/2 marathon time dropped by 20 minutes from 2:08 to 1:45. Also my 10K times dropped from 60+ minutes down to 46 minutes. Not too shabby for an old fart.

Edited by scottknl, 18 December 2011 - 01:52 AM.

[bixbyte]

My experience was similar, to bixbyte's but I also did CRON at the same time. The result was that my numbers were worse than bixbyes at the start and now similar to his wife's. My personal proof of athletic ability is that my 1/2 marathon time dropped by 20 minutes from 2:08 to 1:45. Also my 10K times dropped from 60+ minutes down to 46 minutes. Not too shabby for an old fart.

_______

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).
Slow down to 3.3 MPH and my heart rate drops down to a normal 111 in under 2 minutes.
Optimal Heart strength is if your heart rate returns to normal in 2 minutes for a runner.
I am very pleased with supplementing on Resveratrol.

[bixbyte]

My experience was similar, to bixbyte's but I also did CRON at the same time. The result was that my numbers were worse than bixbyes at the start and now similar to his wife's. My personal proof of athletic ability is that my 1/2 marathon time dropped by 20 minutes from 2:08 to 1:45. Also my 10K times dropped from 60+ minutes down to 46 minutes. Not too shabby for an old fart.

_______

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).
Slow down to 3.3 MPH and my heart rate drops down to a normal 111 in under 2 minutes.
Optimal Heart strength is if your heart rate returns to normal in 2 minutes for a runner.
I am very pleased with supplementing on Resveratrol.

____________________________________


Today, After 45 minutes of running at 4.0 MPH on the treadmill.
I ran 4.8 MPH on the treadmill for five minutes my heart rate moved up to 150 Beats.
Then I slowed down to 2.2 MPH and my heart rate returned to the normal 111 Beats in 2.5 Minutes.
If I was an athlete need 163 BPM and should take 2 minutes to return to the normal 111 beats.
Resveratrol supplements appear to be helping my Cardiovascular fitness.
I am having my trouble upping my heart rate since my joints can ache afterwards.
220 - (my age) 57 = 163 Beats and then down to my normal 111 Beats in two minutes is an Athlete.
I can not run fast enough to make 163 beats.
But, I keep trying.

DOSE:
1,500 Milligrams per Day 99% Resveratrol
25 Milligrams Ploydatin
20 Milligrams Piperine

Edited by bixbyte, 17 January 2012 - 07:07 AM.

[Mind]

My experience was similar, to bixbyte's but I also did CRON at the same time. The result was that my numbers were worse than bixbyes at the start and now similar to his wife's. My personal proof of athletic ability is that my 1/2 marathon time dropped by 20 minutes from 2:08 to 1:45. Also my 10K times dropped from 60+ minutes down to 46 minutes. Not too shabby for an old fart.

_______

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).
Slow down to 3.3 MPH and my heart rate drops down to a normal 111 in under 2 minutes.
Optimal Heart strength is if your heart rate returns to normal in 2 minutes for a runner.
I am very pleased with supplementing on Resveratrol.

____________________________________


Today, After 45 minutes of running at 4.0 MPH on the treadmill.
I ran 4.8 MPH on the treadmill for five minutes my heart rate moved up to 150 Beats.
Then I slowed down to 2.2 MPH and my heart rate returned to the normal 111 Beats in 2.5 Minutes.
If I was an athlete need 163 BPM and should take 2 minutes to return to the normal 111 beats.
Resveratrol supplements appear to be helping my Cardiovascular fitness.
I am having my trouble upping my heart rate since my joints can ache afterwards.
220 - (my age) 57 = 163 Beats and then down to my normal 111 Beats in two minutes is an Athlete.
I can not run fast enough to make 163 beats.
But, I keep trying.

DOSE:
1,500 Milligrams per Day 99% Resveratrol
25 Milligrams Ploydatin
20 Milligrams Piperine

Don't run so fast as to damage your heart. Don't be the marathoner (exerciser) who keels over dead. There are some natural limits, not meant to be passed and it seems to change with age. I would hate to see such a good contributor to the forums/Longecity all of a sudden go quiet.

Edited by Mind, 17 January 2012 - 09:11 PM.

[hmm]

bixbyte, it seems to me that even after years, you remain quite stunned at the prospect of finding out that you are a bit of an athlete. I spent a few years once working for a major computer company that was chock full of nerds. Some of these guys, I realized after I got to know them a bit, were actually strong as bulls but hardly realized it because they led a life of the mind. Might you be one of those types (and your wife as well) who never really realized what athletes they always really were? I am wondering if taking rsv has finally liberated you psychologically and allowed you to express yourself (physically) the way nature always intended?

[Anthony_Loera]

Bixbyte,

I really like your regimen! I would add a bit of curcumin to it, but otherwise, it's really good.

Cheers
A

Edited by Anthony_Loera, 18 January 2012 - 05:08 PM.

[platypus]

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).

How is that "ideal"?

[platypus]

Don't run so fast as to damage your heart. Don't be the marathoner (exerciser) who keels over dead. There are some natural limits, not meant to be passed and it seems to change with age. I would hate to see such a good contributor to the forums/Longecity all of a sudden go quiet.

I don't think short bursts of high intensity damage the heart - it's the marathon etc. that are dangerous. Or are you saying one should never venture close to one's maximum pulse?

[scottknl]

I asked longevity researcher Dr. Luigi Fontana about why endurance athletes die from heart arrhythmia. His response was that the endurance exercise damages the pathways (nerve?) that trigger the heart beats after a lifetime of extreme exercise. I didn't have time to get into the mechanism by which this happens though. There's probably some kind of happy medium level of aerobic exercise that will allow a full 150 year life span without triggering heart problems.

[bixbyte]

AM normal dose 1,500 mg Res + 25 mg Polydatin + 10 mg piperine.
Today 15 minutes before treadmill. I wet my index finger and touch 98-99% Pure Resveratrol.
Put the finger with RES powder under my tongue and left the dry RES powder to stay under my tongue.
Ran on the treadmill at 4.8 Miles per hour for 6 minutes.
My Heart Rate moved up to 142 BPM.
Reduced the Treadmill to 3.1 MPH and in 2 minutes my Heart Rate returned the the normal 110 Beats per minute.
Got the ideal return to normal Heart Rhythm in two minutes.
Then I did my remaining run at 4.0 MPH for my one hour workout on the treadmill.
Appears sublingual res is a Cardioprotectant?
I need others runners to share their experiences.

[bixbyte]

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).

How is that "ideal"?

220 - Your Age = Max Heart Rate (my max is 163)
After you reach your Max you must be able to restore your normal Heart Rate in Two minutes.
Then you can be called "Athlete"
Some people their heart can beat erratic and die trying this experiment.
So, I suggest you proceed with caution.
But, I can not push my heart rate up to my Max
I think the resveratrol is a cardioprotectant or maybe I am a natural athlete.
But I do not think I am a natural athlete since my wife is taking the same dose of Res.
She can run faster than I.
My wife is shorter and lighter weight so I believe the same dose is actually 25% more resveratrol in her blood stream..
I look at my wife's blood test results and I see a perfect lipid profile.
My blood tests results are close to great but her results are better and she is faster.
Years of a large daily dose of 98 and 99% Resveratrol.

[platypus]

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).

How is that "ideal"?

220 - Your Age = Max Heart Rate (my max is 163)
After you reach your Max you must be able to restore your normal Heart Rate in Two minutes.
Then you can be called "Athlete"
Some people their heart can beat erratic and die trying this experiment.
So, I suggest you proceed with caution.

Sure, but if you don't have pre-existing issues and are in decent shape, you should strive towards working closer to your max heartrate. Besides, your actual Max heartrate might be higher than 163, you'll only know if you try reaching it.

BTW one thing to conseder is the Heart Rate Reserve, i.e. the difference between your resting pulse and your real Max HR. 110 sounds pretty high for a resting pulse, is that really where you're at when you wake up in the morning & before ytou get out of bed?

But, I can not push my heart rate up to my Max

A treadmill is not so good for trying to get to Max HR. You could for example try intervals on an elliptical machine or doing kettlebell swings.

[scottknl]

I can run 4.5 MPH on treadmill for 5 minutes to up my heart rate to 140 (ideal is 142).

How is that "ideal"?

220 - Your Age = Max Heart Rate (my max is 163)
After you reach your Max you must be able to restore your normal Heart Rate in Two minutes.
Then you can be called "Athlete"
Some people their heart can beat erratic and die trying this experiment.
So, I suggest you proceed with caution.
But, I can not push my heart rate up to my Max
I think the resveratrol is a cardioprotectant or maybe I am a natural athlete.
But I do not think I am a natural athlete since my wife is taking the same dose of Res.
She can run faster than I.
My wife is shorter and lighter weight so I believe the same dose is actually 25% more resveratrol in her blood stream..
I look at my wife's blood test results and I see a perfect lipid profile.
My blood tests results are close to great but her results are better and she is faster.
Years of a large daily dose of 98 and 99% Resveratrol.

Resveratrol has been shown to improve remodeling of arterial wall thickness for maximum opening for blood flow. The areas with too thin walls are built up and the areas with too thick walls slim down. Also perfusion/repurfusion injury (temporary blockage) outcomes are also improved by resveratrol.

I'll have to test my own response to your athlete protocol, thanks for letting me know Bix. My resting heart rate is often in the low 50's or high 40's BPM. I can easily push my heart rate up past the max for my age, but I don't know the recovery time yet. Too much snow for running now. Maybe in a couple of months I can test it. I've also been meaning to do a beep test (aka bleep test) and figure out my V02 max. You tube has several videos on this. I'm willing to bet that I can come close to athlete performance on the V02 tests after 2 or 3 tune-up runs of 10 Km.