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Is there a way to kill libido w/o impairing normal function?

libido ssri testosterone antipsychotic sexuality

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#1 khemix

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Posted 29 January 2012 - 11:26 PM


SSRIs damp libido but give no motivation to do anything but to stay in bed all day.

Antipsychotics sort of damp libido but at the cost of turning you into a zombie with no motivation or energy.

Lowering testosterone does the trick too, but seriously screws with energy levels and memory.


Is there anything out there that is more local in lowering just libido and not global so as to effect normal function, specifically motivation and energy. It seems you can't get one without the other. I was thinking maybe norepinephrine as there are stories with Straterra killing the mojo. How about a selective antagonist that targets say D3 receptors. Or alternatively, is there a way to boost energy levels without turning into a sex maniac the way you do with stimulants?

Edited by khemix, 29 January 2012 - 11:27 PM.

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#2 beatsme

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Posted 30 January 2012 - 01:11 AM

Technology isn't always the answer. A strong libido is a sign that you're healthy, and young. Just masturbate more... seriously.
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#3 abelard lindsay

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Posted 30 January 2012 - 01:30 AM

I find that Acetyl-L-Carntine reliably kills my libido for a few hours after taking it.
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#4 chroncile

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Posted 30 January 2012 - 04:27 AM

Why would you want to dampen your libido? My sex drive is incredibly low even though I'm an 18 year old male. Anyway, I found that piracetam further decreased my already low libido.
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#5 DoomAndGloom

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Posted 30 January 2012 - 11:40 AM

Why would you want to dampen your libido? My sex drive is incredibly low even though I'm an 18 year old male. Anyway, I found that piracetam further decreased my already low libido.


I've thought about dampening my own sex drive before, and perhaps my reasons are different from the original poster, but for me its because... I kind of feel like it can get in the way of normal functioning at times. Masturbating takes minutes (even if just a few) out of your day that could be spent doing other things, so does just regular sex, and I currently don't have a partner to have regular sex with any way so that removes the social benefits. I also feel that sex drives modify my reasoning some what and may add to bias (toward people I find attractive for instance), which I don't like. Continuing with that same vein, I don't like how something so primitive can control me.

People have varying sex drives. Maybe you want to increase yours, maybe others want to decrease theres, and some are just fine. Its all personal.

Edited by DoomAndGloom, 30 January 2012 - 11:41 AM.

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#6 Baten

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Posted 30 January 2012 - 12:01 PM

Libido isn't a bad thing. Do you really want to function like a machine? Oh well.
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#7 Googoltarian

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Posted 30 January 2012 - 03:38 PM

Do you really want to function like a machine? Oh well.

Are you implying that fulfilling sexual needs is not functioning like machine? ;)
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#8 nowayout

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Posted 30 January 2012 - 03:51 PM

What's wrong with you? Are you a sex offender? Are you unhappy with your sexual orientation? Drugs are not the answer.
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#9 manic_racetam

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Posted 30 January 2012 - 06:17 PM

People have different reasons for wanting to lower sex drive. On this board it seems to usually be related to having an over-active sex drive that gets in the way of studying, work, or some other important activity.

In response to the OP, some people find that dosing around 75mg a day of Noopept lowers sex drive, and that doesn't seem to carry other negative side effects (subjectively at least). Long-term effects are unknown but it may prove to be a positive short-term solution if you get that side effect.
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#10 nupi

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Posted 30 January 2012 - 07:09 PM

Bacopa is worth a shot but you'll have to try whether it will affect motivation/energy a lot...

#11 Lufega

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Posted 30 January 2012 - 09:03 PM

People have different reasons for wanting to lower sex drive. On this board it seems to usually be related to having an over-active sex drive that gets in the way of studying, work, or some other important activity.


That was exactly my problem. I find that curcumin numbs my libido quite noticeable.
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#12 MrHappy

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Posted 30 January 2012 - 11:22 PM

Agree with nupi - bacopa, at night.



#13 nowayout

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Posted 31 January 2012 - 12:02 PM

One day you might want your libido back. You may never be able to get it back.

The internet is full of desperate young men who lost their libido (and other things such as motivation, clarity of thought, etc.) permanently because of certain drugs or supplements. See for example propeciahelp.com. Some have been driven to suicide because of this.
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#14 nupi

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Posted 31 January 2012 - 12:53 PM

Maybe it's just me, but one of these days someone needs to explain me why the absence of desire for something is inherently a problem. The desire and the inability to execute on it, sure, but absence of sexual desire on its own, how can that be an issue? Unless of course there is something like a meta-desire for sex...

But granted, with motivation I see a much bigger issue as it is far more all-encompassing

Edited by nupi, 31 January 2012 - 12:53 PM.

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#15 Elus

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Posted 31 January 2012 - 08:28 PM

Newton was asexual. I want to be like him. I don't want sexual attraction distracting me from my work. I do not like being controlled in this very specific way, just as I don't like being addicted to a drug.

In some way, sex is the addiction we're all born with (i.e. we desire it impulsively). I want to eliminate this impulse from my own body, but I'm just fine if people desire to keep it in theirs. However, I also want to make sure it doesn't come at the cost of my own cognitive abilities.

I made a thread like this one as well: http://www.longecity...__fromsearch__1

Edited by Elus, 31 January 2012 - 08:31 PM.

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#16 hooter

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Posted 31 January 2012 - 11:52 PM

Try meditation, entheogens and piracetam. I am personally seeing results from this. I am slowly learning how to control my mind into shapes and forms that I desire. I can regulate my libido already to some extent. I don't react with hostility when proven wrong on anything and I'm trying to manage the same for emotions. I already find more beauty in knowledge than art, more depth in non-fiction and fiction and more motivation from learning than anything else. I want the ability to switch from very empathic to complete sociopath at will, from autistic to charismatic, from naive to perceptive. I want to to see all edges of the diamond.

However, there is the downside of becoming less familiar with 'regular' thoughts and established norms. Culture becomes horrifying. Taking the mask off everything isn't pleasant, sometimes deception is necessary to function. To see beyond is a burden and quite alienating. Make your decision accordingly.

Note that I would advise against trying to forcibly become asexual, as one is extremely likely to screw something up to an extraordinary level that way.

Edited by hooter, 31 January 2012 - 11:59 PM.

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#17 pedr0vsky

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Posted 03 February 2012 - 05:37 PM

khemix, is this the problem?

http://en.wikipedia....llness_syndrome

#18 JChief

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Posted 03 February 2012 - 06:32 PM


Is there a way to kill libido w/o impairing normal function? imagining your grandmother naked. :wub:

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#19 Baten

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Posted 03 February 2012 - 06:48 PM

Is there a way to kill libido w/o impairing normal function? imagining your grandmother naked. :wub:


Haha :-D not much of a long-term ideal solution though.

#20 Ampa-omega

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Posted 16 February 2012 - 04:42 AM

are there any known natural anti psychotics? would be useful in this situation

maybe load up your cholinergic system and that should lower dopamine receptor activity?
antihistamines? stuff to mellow out like kava or Holy Basil, which is anti anxiety and an anti androgen. high dosed indole carbinol should lower sex steroid hormones. statins lower cholesterol. methylene blue is a cGMP inhibitor so possible it could inhibit erections if dosed very high

Edited by Ampa-omega, 16 February 2012 - 05:40 AM.


#21 Ampa-omega

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Posted 16 February 2012 - 06:26 AM

mushrooms i heard have lithium and a dht and aromatase inhibitor so you could try eating a lot of mushrooms , any where around 10 or more. worth a shot. theres some stuff on the wiki page for anti androgens http://en.wikipedia....#Phytochemicals, not reccomending for a daily solution only for 'those' days you really need it. nootropics seem like a better daily solution, noopept as example.

Edited by Ampa-omega, 16 February 2012 - 06:43 AM.


#22 ultranaut

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Posted 16 February 2012 - 09:26 PM

I was thinking maybe norepinephrine as there are stories with Straterra killing the mojo. How about a selective antagonist that targets say D3 receptors. Or alternatively, is there a way to boost energy levels without turning into a sex maniac the way you do with stimulants?


Straterra made me insanely horny but totally destroyed my ability to perform. It also made me feel like shit. Worst drug I've ever taken.

Ritalin definitely killed my sex drive (along with my sense of humor).

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#23 hippocampus

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Posted 16 February 2012 - 11:59 PM

Milk thistle can lower libido (because it increases prolaction) and has many health benefits (although no human long-term studies yet ...).
I also agree with hooter, meditation may help you control your libido without lowering it (and I also imagine that if you don't masturbate for a longer time you'll have lower libido - which will rise quickly if you begin masturbating again). OTOH, if you are addicted to masturbation/sex, lowering libido may not be the best answer. If your only motive is that you want more time for work you can also do some other lifestyle changes (afterall you only need to save <15 minutes a day).

#24 Elus

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Posted 17 February 2012 - 11:40 PM

http://en.wikipedia....morphic_nucleus

Role of SDN in controlling of male sexual behaviors

Male sexual behaviors can be divided into two phases: the appetitive phase, which contains highly variable sequence of behaviors such as attracting and courting, and the consummatory phase, during which highly stereotyped copulatory behaviors occur. The medial preoptic area of the brain is considered to control the expression of both male copulation and male appetitive sexual behavior. It is found that large lesions of SDN-POA severely disrupt copulatory behavior in rats. Also, cell-body lesions of SDA pars compacta (ahomologue of SDN-POA) in gerbils produce severe disruptions of male copulatory behavior. Moreover, a study on medial preoptic nucleus (POM) (homologue of medial preoptic nucleus in rats) in quails showed that the activation of male copulatory behavior requires the aromaticity of androgen (testosterone) into an estrogen (17β-estradiol). Like in SDN-POA, aromatase-expression neurons are a specific marker of the nuclear boundary of POM in quails. The intensity of male copulatory behavior is found to positively correlate with the number of the aromatase-expression neurons in the caudal part of POM.[2]

Appetitive behaviors are also partly controlled by medial preoptic area as aromatase-knockout mice show deficits in sexual motivation. However, appetitive behaviors are disrupted by the lesions in rostral part rather than caudal part of medial preoptic area. Lesions of the rostral part of medial preoptic area also diminish preference for female by male rats. Furthermore, in vivo dialysis experiments showed that the level of extracellular dopamine in the mPOA increases as the sexual appetitive sequences progress. mPOA’s involvement in the control of appetitive sexual behaviors is also confirmed by pharmacological manipulations of the dopaminergic system in it. In rats, lesions to mPOA can eliminate the male copulatory behavior but can only diminish appetitive behavior, which suggests that some other parts of the brain, except for mPOA, are also responsible for sexually appetitive behavior.[2]


Also, here is a paper on the biological basis for libido:

The Biological Basis for Libido

Edited by Elus, 18 February 2012 - 12:12 AM.


#25 nowayout

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Posted 17 February 2012 - 11:56 PM

Elevating prolactin, as someone suggested, is NOT good for you. And lowering testosterone, or knocking out its receptors, which come down to the same thing, could be terrible for general health. Sex hormones are not just for sex - they play a role in miriads of other processes in the body fundamental for life, including regulating bone density, endothelial function, insulin sensitivity, and mood - indeed, withdrawing testosterone from the brain is well known to cause terrible depression. And low testosterone in men is associated with a significant early morbidity and mortality.

#26 Elus

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Posted 18 February 2012 - 12:02 AM

Elevating prolactin, as someone suggested, is NOT good for you. And lowering testosterone, or knocking out its receptors, which come down to the same thing, could be terrible for general health. Sex hormones are not just for sex - they play a role in miriads of other processes in the body fundamental for life, including regulating bone density, endothelial function, insulin sensitivity, and mood - indeed, withdrawing testosterone from the brain is well known to cause terrible depression. And low testosterone in men is associated with a significant early morbidity and mortality.



Precisely right. Which is why we won't do this.



Anyway guys, check this out:

http://www.ncbi.nlm....pubmed/16135375

Free Full paper Here: Attached File  Dopamine_Male_Sex_Behavior.pdf   529KB   7 downloads

Dopamine, the medial preoptic area, and male sexual behavior

The medial preoptic area (MPOA), at the rostral end of the hypothalamus, is important for the regulation of male sexual behavior. Results showing that male sexual behavior is impaired following MPOA lesions and enhanced with MPOA stimulation support this conclusion. The neurotransmitter dopamine (DA) facilitates male sexual behavior in all studied species, including rodents and humans. Here, we review data indicating that the MPOA is one site where DA may act to regulate male sexual behavior. DA agonists microinjected into the MPOA facilitate sexual behavior, whereas DA antagonists impair copulation, genital reflexes, and sexual motivation. Moreover, microdialysis experiments showed increased release of DA in the MPOA as a result of precopulatory exposure to an estrous female and during copulation. DA may remove tonic inhibition in the MPOA, thereby enhancing sensorimotor integration, and also coordinate autonomic influences on genital reflexes. In addition to sensory stimulation, other factors influence the release of DA in the MPOA, including testosterone, nitric oxide, and glutamate. Here we summarize and interpret these data.


Now we're getting a lot more selective...


Edited by Elus, 18 February 2012 - 12:11 AM.

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#27 Ampa-omega

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Posted 18 February 2012 - 12:40 AM

Good Stuff Elus Good stuff. most of the suggestions here should be focused on getting more selective. Why i haven't bothered to look into the mechanisms of libido is beyond me, i must of been too ocd with my other interest, I'll remind myself to look into it like you have when i have the time and energy.
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#28 Ampa-omega

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Posted 18 February 2012 - 12:43 AM

Elevating prolactin, as someone suggested, is NOT good for you. And lowering testosterone, or knocking out its receptors, which come down to the same thing, could be terrible for general health. Sex hormones are not just for sex - they play a role in miriads of other processes in the body fundamental for life, including regulating bone density, endothelial function, insulin sensitivity, and mood - indeed, withdrawing testosterone from the brain is well known to cause terrible depression. And low testosterone in men is associated with a significant early morbidity and mortality.


yes that is true, although there are people who function fine even with lower sex hormone/neurosteroid levels. I Think you are right on, it was just a off the line suggestion, that should in fact be more targeted and specified.

#29 lucid

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Posted 18 February 2012 - 01:04 AM

#1 Try CR. It doesn't impair function but will certainly lower drive.

#2 Put a porn-blocker on your comp and give up porn / masturbation for a while. Oddly enough it will really lower your drive and improve your performance. Six part youtube video see here.

Tried both, both work.
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#30 sam7777

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Posted 18 February 2012 - 08:50 AM

Porn is disasterous for controlling sex drive. Really that one will get you.

Kava, milk thistle, holy basil, herbal cholinergics all made me hornier. Just about any damn herb makes me hornier. But piracetam killed my sex drive so bad, that was the single reason I never would take the stuff.



Also tagged with one or more of these keywords: libido, ssri, testosterone, antipsychotic, sexuality

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