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Nardil (phenelzine) and ADHD drugs

lourdaud's Photo lourdaud 31 Jul 2012

I'm soon going to start a phenelzine trial for atypical depression and as you probably know you have to be careful with food drug interactions when you're on this drug.

I suffer from pretty severe ADHD though and I really need something to help with focus.

I've looked around a bit on the web and anecdotally modafinil should be just fine, which is a great thing as it's the best drug I've tried for ADHD.

Unfortunately modafinil alone doesn't quite cut it, but together with bupropion it helps significantly.

What do you think, would bupropion be too much?? I'd stay with a low dose (150 mg) but bupropion does seem to raise NE quite a lot so it feels a bit risky.. :|o
I read about someone who was on Nardil + 60 mg of dexamphetamine who was having no problems at all but I'm not sure how dex compares to bupropion..
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khemix's Photo khemix 01 Aug 2012

Nardil is a MAO and inhibits the reuptake of norepinephrine and dopamine. Wellbutrin also does this also and this may cause a lot of these neurotransmitters to remain floating around which can result in hypertension or mania. I don't think any sensible doctor will prescribe the two unless doses are carefully checked.
Edited by khemix, 01 August 2012 - 03:30 AM.
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