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Cheese and fertility decline

estradiol fertility cheese

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#1 Fred_CALICO

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Posted 27 December 2012 - 02:13 PM


Translated via Google : http://www.lanutrition.fr/les-news/la-qualite-du-sperme-en-fort-declin-en-france.html


A new study of more than 26,600 men confirms, according to others, a decline in "significant" concentration of sperm sperm quality and in France. Between 1989 and 2005, the decrease of the concentration is continuous (1.9% per year) for a total reduction of 32.2%. Thus, in a man of 35 years, the number of spermatozoa increased from 73.6 million / ml to 49.9 million / ml on average.

The study was published Tuesday, December 4 in the journal Human Reproduction.
http://humrep.oxford...415.short?rss=1

It also shows that the proportion of normally shaped sperm is also down 33.4% over the same period.

But the reality may be even grimmer because the sample studied (partners of infertile women) have a profile healthier than the general population of smokers with less and less obese.

Sperm concentrations theoretically remain in the area for fertility according to WHO criteria (more than 15 million / ml). But according to some studies, concentrations below 55 million / ml could affect reproduction and delay the time of conception.

"To our knowledge, the authors write, this is the first study finding a reduction in severe and general sperm concentration and morphology at the scale of an entire country and a significant period. (... ) This is a serious warning. "They add that "the relationship with the environment in particular must be determined."

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http://www.lanutriti...-du-sperme.html


As the great French study published yesterday, which caused a stir in the newsroom and probably among couples seeking to have children: sperm quality is in sharp decline in France. Conducted over 26,600 men it shows that between 1989 and 2005, the concentration of sperm decreased by an average of 32.2%. Thus, in a man of 35 years, the number of spermatozoa increased from 73.6 million / ml to 49.9 million / ml on average, a level of concern even if it can still make babies. The proportion of normally shaped sperm is also down 33.4% over the same period.

The study comes on no other, more limited.

For example, a survey conducted in Paris found a decrease of 2.1% per annum of the sperm concentration sperm donors between 1973 and 1992. The researchers also reported that the concentration of sperm of a man aged 30, born in 1945 was 102 million / ml but only 51 million / ml in a man thirty-born in 1962.

To explain the decline in sperm count and the total number of normal sperm, the traditional factors are incriminated: plasticizers, pesticides, drug residues in water beverages, obesity, the same people who were singled out in the years 1990 when I followed these issues Sciences et Avenir and it became clear that something was happening at the sperm populations in developed countries. These environmental toxins called "endocrine disruptors" certainly play a role.

But it is only very recently that we began to look at the supply side. And the surprise is waiting for you!

Myriam Afeiche, a researcher at the School of Public Health Harvard presented October 23, 2012 a study that has been much talk at the 68th Meeting of the American Society for Reproductive Medicine, which was held in San Diego (California). She sought an association between diet and sperm quality of 189 young men aged 18 to 22 years from a U.S. study, the Rochester Young Men's Study. Results: Men who consume between 1.3 and 7.5 servings of dairy per day whole less of normal sperm than men who consume little dairy (zero to 1.2 servings per day). The researchers found that compared to others, men who consumed more than three servings of whole dairy products had a 25% drop in sperm quality. A portion corresponded to 30 g of cheese, a spoonful of cream, an ice cream cone or a glass of whole milk.

Dr. Afeiche explains the content of cow's milk in female hormones may explain these changes. Whole cow's milk also more likely to contain pesticides and other pollutants that have an affinity for fat. This may be surprising to discover that there are hormones in cow's milk. There because the cows are milked today for a large part of their pregnancy, which was not the case in the past, as shown by surveys in the tribes of nomadic pastoralists. Production first!

When I Reims Conference in November 2012, I gave some figures. For example, there are between 40 and 55 pg / ml estrone sulfate free and 200 to 370 pg / ml estrone sulfate conjugate in cow's milk. This hormone is not destroyed by sterilization and part is converted by each of us estradiol. Moreover, there are also estradiol in milk. The total estrogen (free and conjugated) can exceed 700 pg / ml in skim milk. Milk fat contain their side very high levels of progesterone.

Japanese researchers who investigate the fertility decline in the country, have found an association with the recent explosion in the consumption of dairy products. They calculated that a boy who consumed the equivalent of 50 cL of milk per day, "receives" 160 ng estrone sulfate, a portion of which is converted to estradiol. A closer 40-100 ng daily that the body produces naturally.

This leads us to the French situation. The French consume about 5 kg of cheese per person per year in 1950. This figure was 18 kg in 1980, 23.5 kg in 2000, a little over 24 kg in 2009. We are the second largest consumers of cheese in Europe (kg / person), behind the Greeks. And we occupy the first place in the consumption of butter (8 kg / person / year).

Here is the hypothesis: a major hormonal changes in our environment over the last 60 years in France, is that we are exposed at an early age to female hormones dairy products, due to the change of the mode of production of milk and our appetite for cheese and butter. This exhibition could at least partly explain the decline in sperm quality that is recognized today.

To test this hypothesis, or the reverse, it would launch a study on the issue. I appeal to the dairy industry ...
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#2 Fred_CALICO

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Posted 27 December 2012 - 02:22 PM

Complement : http://www.ncbi.nlm....pubmed/22895856


Biol Reprod. 2012 Oct 25;87(4):101. doi: 10.1095/biolreprod.112.101634. Print 2012 Oct.

Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial.

Robbins WA, Xun L, FitzGerald LZ, Esguerra S, Henning SM, Carpenter CL.


Source

Center for Occupational and Environmental Health, Fielding School of Public Health, University of California Los Angeles, 90095-1772, USA. wrobbins@sonnet.ucla.edu


Abstract

We tested the hypothesis that 75 g of whole-shelled walnuts/day added to the Western-style diet of healthy young men would beneficially affect semen quality. A randomized, parallel two-group dietary intervention trial with single-blind masking of outcome assessors was conducted with 117 healthy men, age 21-35 yr old, who routinely consumed a Western-style diet. The primary outcome was improvement in conventional semen parameters and sperm aneuploidy from baseline to 12 wk. Secondary endpoints included blood serum and sperm fatty acid (FA) profiles, sex hormones, and serum folate. The group consuming walnuts (n = 59) experienced improvement in sperm vitality, motility, and morphology, but no change was seen in the group continuing their usual diet but avoiding tree nuts (n = 58). Comparing differences between the groups from baseline, significance was found for vitality (P = 0.003), motility (P = 0.009), and morphology (normal forms; P = 0.04). Serum FA profiles improved in the walnut group with increases in omega-6 (P = 0.0004) and omega-3 (P = 0.0007) but not in the control group. The plant source of omega-3, alpha-linolenic acid (ALA) increased (P = 0.0001). Sperm aneuploidy was inversely correlated with sperm ALA, particularly sex chromosome nullisomy (Spearman correlation, -0.41, P = 0.002). Findings demonstrated that walnuts added to a Western-style diet improved sperm vitality, motility, and morphology.


PMID: 22895856 [PubMed - in process] Free full text


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Robbins WA, Xun L, Fitzgerald LZ, Esguerra S, Henning SM, Carpenter CL. Walnuts Improve Semen Quality in Men Consuming a Western-Style Diet: Randomized Control Dietary Intervention Trial. Biol Reprod. 2012 Aug 15.


Although the link between the quality of food and the quality of sperm is always highlighted in the story, direct evidence of the impact of different foods lacking. The researchers believe that the modern Western diet may lack certain nutrients and essential fatty acids necessary for fertility.

117 healthy men, aged 21 to 35 have been enrolled in a study to assess the impact of nut consumption on sperm quality. 58 participants were instructed to eat as usual but without the nuts and the remaining 59 people were instructed to continue eating as usual but adding 75 g of walnuts per day for 3 months.

After 3 months, the researchers compared sperm characteristics of both groups. The analyzes show that sperm group who consumed nuts have a better shape and move more easily. More chromosomes present in the semen are better preserved in this group. Finally, blood tests show that the consumption of nuts has increased the omega-3 and omega-6 in the blood.

These results suggest that nut consumption is beneficial for fertility, in addition to many other benefits already known to health. Researchers do not know whether their results are applicable to men who suffer from fertility problems but if that were the case it would be a simple solution to implement.

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#3 Mind

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Posted 27 December 2012 - 06:38 PM

The hormone connection/theory in dairy is interesting. My parents and grandparents generation had zero problems conceiving vast numbers of children even though they consumed large quantities of dairy. However, their dairy products were high fat and organic, not crappy like most of the dairy nowadays.

#4 sthira

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Posted 27 December 2012 - 08:23 PM

Eat walnuts; eat not cheese.

#5 Fred_CALICO

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Posted 27 December 2012 - 08:51 PM

Not, not !
Why not both ?

http://cheese.about....tes/tp/nuts.htm

(Humor)

Edited by sell58, 27 December 2012 - 08:58 PM.


#6 daouda

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Posted 27 December 2012 - 11:01 PM

How can a frenchman manage to live without cheese?

#7 Fred_CALICO

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Posted 28 December 2012 - 12:57 AM

How can a frenchman manage to live without cheese?

Comment un americain peut vivre sans arme ?
Et pourtant ce sont des hommes, Madame !
Ils ont des larmes, comme les autres êtres humain.
Bonne nuité, man daouda.
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#8 nupi

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Posted 29 December 2012 - 02:46 PM

The hormone connection/theory in dairy is interesting. My parents and grandparents generation had zero problems conceiving vast numbers of children even though they consumed large quantities of dairy. However, their dairy products were high fat and organic, not crappy like most of the dairy nowadays.



They presumably also started conceiving children much earlier than most who are struggling today...

I am also not sure if it is the hormones in diary (in any case, it is more than that) as rBST is banned in the EU and fertility (as measured by biomarkers, not birthrate) is on the decline here as well. I find the claims that the huge hormonal loads that the pill puts on water sources and potentially some of the connections that are being made to plastics (if the chemicals can induce sex change in fish they cannot possibly be good for humans) to be more convincing.

Of course, personally I would welcome an alternative, non-invasive contraception method for men but I doubt that I will start to eat plastics because of that :)

Edited by nupi, 29 December 2012 - 02:49 PM.


#9 niner

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Posted 29 December 2012 - 07:49 PM

There has been a long term decline in testosterone levels in American males (compared to the same age cohort, so aging of society isn't a factor), and I suspect you'd probably see this throughout the developed world. I've not seen data to that effect, though, and inter-country differences might provide clues toward causality. I think someone needs to demonstrate that endocrine disruptors like BPA are not responsible for all this, or get them the hell out of our food and lives. Diet is an interesting connection. It should be a simple matter to measure hormone levels and types in dairy and other products, and to relate that to the known effects of such hormone supplementation on humans. We should try to compare that to overall hormone levels in dairy from 50 years (or more) ago, when farming practices were distinctly different. Another factor that plays into some of our modern hormone-related weirdness, like kids hitting puberty at much earlier ages, is simply nutrient excess. We eat too much, particularly protein, crappy carbs, and crappy oils. From 1950 to now, the French have nearly quintupled their cheese consumption. The US situation is similar, though I think not as extreme. Maybe someone should look at the sperm quality of clean paleo, vegan, raw, and CR dieters, and see what they look like.

#10 misterE

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Posted 30 December 2012 - 05:22 AM

I’ve been researching this phenomenon as well. The major cause for the low sperm count and androgen levels observed in western societies (according to my research), is mainly caused by the obesity epidemic. Body-fat converts androgens into estrogens. Estrogens suppress LH and FSH secretion. LH stimulates testosterone production, while FSH stimulates sperm production.

Obviously these hormonal changes that have been occurring have also mirrored the drastic change in diet that occurred in the 20th century and the rise of the obesity epidemic as a result of our dietary shift.

Estrogens in milk defiantly have a negative role. A Japanese study (which was alluded to in the opening post) found that after drinking a pint of milk, a decrease in LH, FSH and testosterone and an increase in estrone in both men and children was observed [1]. Another factor that probably plays a role is the estrogen actually given directly to livestock (cows, chickens, pigs etc.) [2].

Examining the western-diet and how it has changed says a lot. Compared to 1909, Americans are eating more meat, dairy, total fat and total sugar and less whole-grains, beans and potatoes [3-4]. Cheese consumption has gone from 4 pounds per year in 1909 to 33 pounds!

Researchers have actually looked at hormone levels in men eating different diets. Vegan men (eating no dairy) have about 15% higher testosterone levels compared to men eating the typical western diet [5].

Diet and obesity are the two largest contributors to this alarming trend. But there are also many other small factors that also play a negative role like dioxins; synthetic chemicals that accumulate in fat tissue, have been shown to alter hormones involved with fertility. The primary source of dioxins is in animal-fat [6] and especially fish. Pesticides sprayed on produce also have harmful effects on fertility.

So if someone were to ask me how to best avoid this from happening to them, I would advise them to:

1. Eat low on the food chain (eat mostly a plant-based diet); this limits your exposure to dioxins and estrogen found in meat, eggs and dairy products. It also cuts out most saturated-fat that also boosts estrogen levels [7-8].


2. Stay lean, men should keep body-fat percentage below 15%, women should be 20%. Keeping body-fat low, keeps an enzyme called aromatase low. Aromatase is the enzyme that converts androgens into estrogens.

3. Eat organic as much as possible or grow your own food. This limits your exposure to pesticides.

4. Water filtration if you live in a city. Much of the estrogen (which comes from birth control) is recirculated back into the city drinking water.



[1] Pediatr Int. 2010 Feb;52(1):33-8. Exposure to exogenous estrogen through intake of commercial milk produced from pregnant cows. Maruyama K, Oshima T, Ohyama K.

[2] Handb Exp Pharmacol. 2010;(195):355-67. Hormonal growth promoting agents in food producing animals. Stephany RW.

[3] Am J Clin Nutr. 2010 May;91(5):1530S-1536S. Trends in food availability, 1909-2007. Barnard ND.

[4] Am J Clin Nutr January 1959 vol. 7 no. 1 91-97. The American Diet—Past and Present. Trulson MF.

[5] Br J Cancer. 2000 Jul;83(1):95-7. Hormones and diet: low insulin-like growth factor-I but normal bioavailable androgens in vegan men. Allen NE, Appleby PN, Davey GK.

[6] http://www.epa.gov/p...ubs/dioxins.htm


[7] Am J Clin Nutr. 1986 Dec;44(6):945-53. The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women. Goldin BR, Adlercreutz H, Gorbach SL.


[8] Am J Med. 1985 Jan;78(1):23-7. Effects of a high-complex-carbohydrate, low-fat, low-cholesterol diet on levels of serum lipids and estradiol. Rosenthal MB, Barnard RJ, Rose DP.

Edited by misterE, 30 December 2012 - 05:37 AM.


#11 Luminosity

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Posted 30 December 2012 - 05:29 AM

I believe that the dairy in France is organic and often raw as well. There are a lot of exposures to estrogenic chemicals now but I think they mostly come from food and chemicals in the environment. I believe that they help cause obesity too. Body fat can cause estrogen, at least in women, but I think that most estrogenic exposures are from other sources.

When I was young, males did not have man boobs, including most heavy males. Girls did not have their periods at nine.

#12 nupi

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Posted 30 December 2012 - 12:28 PM

Vegan men (eating no dairy) have about 15% higher testosterone levels compared to men eating the typical western diet [5].



Would be a lot more interesting to compare them to lacto-vegetarians to have a somewhat comparable base line (arguably, vegetarians and vegans are more health conscious than the average population so that would have a major confounding effect). The typical western diet is so screwed up as to be a pretty worthless base-line.

#13 daouda

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Posted 30 December 2012 - 12:53 PM

It also cuts out most saturated-fat that also boosts estrogen levels [7-8].

I thought I remembered that saturated fats were actually "good for T" (T being derived from cholesterol)
A little googling later, found that article (disregard the cheesy background, it seems well-researched)
http://www.t-nation....sterone_booster
Could you comment on it? It also contains a reference that shows the opposite of that study you mentionned ;
Male vegetarians have been shown to have lower levels of plasma Testosterone compared to their meat eating counterparts(4).
4. Howie BBJ, Shultz TTD. Dietary and hormonal interrelationships among vegetarian Seventh-Day Adventists and nonvegetarian men. The American journal of clinical nutrition 1985;42:127-34.

#14 misterE

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Posted 30 December 2012 - 02:57 PM

Would be a lot more interesting to compare them to lacto-vegetarians to have a somewhat comparable base line


Actually that is exactly what the study did. They compared vegans, vegetarians and men eating the standard western diet. Vegan men had 8% more testosterone than vegetarians and 15% more than those eating the western-diet.

#15 misterE

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Posted 30 December 2012 - 03:10 PM

Could you comment on it? It also contains a reference that shows the opposite of that study you mentionned ;




In the short-term saturated-fat boosts free-testosterone (mainly by lowering SHBG, which isn't healthy anyhow), but long term saturated-fat is quite estrogenic, that is why saturated-fat is condemned in causing breast and prostate cancer (both estrogenic cancers). Plus animal-fat (just like human body-fat) contains aromatase-enzymes! So when people are eating animal-fat, they are literally eating aromatase.

#16 Hebbeh

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Posted 01 January 2013 - 01:42 AM

http://extremelongev...olong-lifespan/

Evidence Suggests Blue Cheese May Prolong Lifespan

Dietary choices play an unquestionable role in health and longevity, though just how much is uncertain. We understand much about what foods are health promoting, but new evidence finds a surprising addition to that list.
A new report raises the possibility that aged moldy cheese may be protective of health. This may come as a bit of a surprise considering that cheese isn’t usually considered a very healthy food choice. Since it contains saturated animal fats, high calories and high salt usually cheese consumption is not recommended.
The new paper asserts that cheese may be a key ingredient of the French paradox, the name given to the observation that French have long lifespans and low disease rates despite an apparently poor high fat diet. To this point, much of the French paradox has been attributed to regular red wine consumption and its attendant high resveratrol exposure.
In the current report, the authors review data suggesting that it may actually be the cheese French eat, particularly the molded variety, which promotes health and longevity.
They point out there is good data that cheese consumption reduces LDL levels and lowers blood pressure, both factors that would reduce the incidence of heart disease. Furthermore, they note that cheese lowers serum markers of inflammation including c-reactive protein, tumor necrosis factor, and interleukins 6 and 8. Lower levels of these compounds are associated with reduced disease risk, cancer risk, and mortality.
The reason for these effects, the authors explain, is the fact that while cheese is ripening, the active bacteria produce numerous novel exogenous peptides and macromolecules that may have beneficial biological effects in humans.
Some of these compounds reduce angitotensin converting enzyme (ACE) which reduces blood pressure. Others reduce clotting.
They also point out that blue cheeses have even more such benefit due to the unusually intensive activity of the bacteria used in these products, P. Roqueforti.
They write:


“The core of ripened molded cheeses contains a unique variety of substances…that are not present in other cheeses. In particular, Roquefort and other blue cheeses contain andrastins A–D which are potent inhibitors of…cholesterol biosynthesis. Andrastin A is also known to display strong antitumor activities, suggesting its anti-cancer potential . Other substances, including roquefortine, have strong anti-bacterial properties.”

They also show that geographic variation in good health is linked to rates blue cheese consumption. Further not only does the typical French diet contain abundant amounts of this cheese, but so too does the popular and health promoting Mediterranean diet.
The authors point out long term controlled studies looking at the effects of blue cheese on disease need to be performed.

http://extremelongev...oads/cheese.pdf
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#17 Adaptogen

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Posted 01 January 2013 - 10:06 AM

so blue cheese is healthy?? that is excellent news. i have been eating so much blue cheese lately and was curious as to if it was unhealthy

#18 misterE

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Posted 03 January 2013 - 01:58 AM

I don't know... blue-cheese is still made from cow milk. And cow milk is (one of) the main source(s) of estrogen in the western-diet, plus it contains saturated-fat and cholesterol, both of which have been shown (in hundreds, if not thousands of studies) to promote cardiovascular-disease and insulin-resistance.



As for the claim that cheese eating can lower LDL cholesterol… I have to challenge that claim and ask for a citation. Eating saturated-fat and cholesterol raises LDL! Dairy products contribute more saturated-fat in the western-diet than any other food stuff.

Plus, as I mentioned earlier cheese consumption has increased from 4 pounds per person a year… to a whopping 34 pounds per person per year… I don’t think we need to be eating anymore cheese any time soon, unless you don’t want to give it up and keep convincing yourself its good for ya.

If you can look past your dinner plate, perhaps you will see that dairy is detrimental to your health, the animals' health and the health of the planet.

#19 Adaptogen

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Posted 03 January 2013 - 02:03 AM

yeah dairy is terrible. i have completely stopped drinking milk, although i would drink raw milk if i had a good source nearby.

but i do love a good quality cheese. the harder and saltier the better

#20 nupi

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Posted 03 January 2013 - 10:13 AM

Plus, as I mentioned earlier cheese consumption has increased from 4 pounds per person a year… to a whopping 34 pounds per person per year… I don’t think we need to be eating anymore cheese any time soon, unless you don’t want to give it up and keep convincing yourself its good for ya.


You most definitely cannot compare the yellow plastic that is passed off as cheese in the US to proper European cheese (which is what the French would eat).

Dietary cholesterol and saturated fats have a relatively small impact on your blood cholesterol so arguing you should not eat cheese on that grounds is pretty silly (in facts, MCTs improve blood lipids if anything). Arguing that you should limit arachidonic acid is more defensible but then again, in an otherwise solid diet, I do not see that as a major issue.
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#21 Adaptogen

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Posted 03 January 2013 - 10:15 AM

Plus, as I mentioned earlier cheese consumption has increased from 4 pounds per person a year… to a whopping 34 pounds per person per year… I don’t think we need to be eating anymore cheese any time soon, unless you don’t want to give it up and keep convincing yourself its good for ya.


You most definitely cannot compare the yellow plastic that is passed off as cheese in the US to proper European cheese (which is what the French would eat).

Dietary cholesterol and saturated fats have a relatively small impact on your blood cholesterol so arguing you should not eat cheese on that grounds is pretty silly (in facts, MCTs improve blood lipids if anything). Arguing that you should limit arachidonic acid is more defensible but then again, in an otherwise solid diet, I do not see that as a major issue.


Ah, the classic Swiss cheese defense ;)

#22 nupi

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Posted 03 January 2013 - 10:31 AM

Adaptogen: As I am somewhat lactose intolerant, I do not even eat that much cheese (the only Swiss cheese I can bear is Gruyere, in any case). And I hate the taste of milk, so I am definitely not what you would call a diary apologist :)

#23 misterE

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Posted 08 January 2013 - 04:28 AM

Dietary cholesterol and saturated fats have a relatively small impact on your blood cholesterol





Saturated-fat and cholesterol boosts total and LDL cholesterol and are the two nutrients mostly associated with heart-disease... And there are plenty (thousands) of studies that back that up!


Ornish and Esselstyn; the two doctors who have actually reversed atherosclerosis, used diets extremely low, not only in saturated-fat, but total-fat (to about 15% of total calories) and free of cholesterol (0mg).

Edited by misterE, 08 January 2013 - 04:30 AM.

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#24 niner

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Posted 08 January 2013 - 01:16 PM

Ornish and Esselstyn; the two doctors who have actually reversed atherosclerosis, used diets extremely low, not only in saturated-fat, but total-fat (to about 15% of total calories) and free of cholesterol (0mg).


Hasn't William Davis reversed atherosclerotic plaque in a number of people using a low carb diet, along with certain nutrients?

#25 The Immortalist

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Posted 08 January 2013 - 07:36 PM

There has been a long term decline in testosterone levels in American males




Posted Image

Edited by The Immortalist, 08 January 2013 - 07:38 PM.


#26 misterE

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Posted 11 January 2013 - 03:54 AM

Hasn't William Davis reversed atherosclerotic plaque in a number of people using a low carb diet, along with certain nutrients?






No, I don't believe he has. If so, he never published his results in the peer-reviewed scientific literature.

Are you aware of any peer reviewed studies (in general) showing reversal of atherosclerosis on a low-carb diet?

Edited by misterE, 11 January 2013 - 03:54 AM.

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