you reckon there's any truth to the TCM lore that ginseng should not be consumed with tea? I came across an ebay listing a while back recommending against consumption with tea or radish. Curiously, there was actually some supporting evidence for the radish claim: Effect of Raw Radish on Pharmacological Action of Ginseng, but I could never track down much about taking KRG with tea.
good question, it's hard to say. I tried to find the full article but kept getting errors; it would be interesting to know about the suspected mechanism, active constituents in radish, type of radish, speculations, etc.
My experience has been they are fine to mix in low amounts. Ginkgo and ginseng has been more anxiety inducing for me, as one antagonists GABA-A and the other GABA-B. It's possible ginseng oppose theanine on these grounds, but seems weak speculation at best, and sometimes opposites compliment especially with partial agonists, pre-synaptic sites, long-term effects, convoluted neural pathways and feedback circuits.. it becomes complicated
i know green tea can reduce uptake of other nutrients, but it can also increase delivery of huperzine in albumin to the brain.. so it's kind of a shot in the dark with drug delivery and kinetics.
epi-genetic downregulation may be another thing to watch out for. if green tea slows down methylation and ginseng slows down acetylation and phosphorylation, then combining heavy doses at the same time could really reduce the proteins produced by your cells, resulting potentially even in malaise and fatigue, brain fog and other undesired and paradoxical effects. it could be reminiscent of a small dose of ricin, a ribosome inhibiting and golgi apparatus suffocating poisin which usually kills in 3-5 days and was fired from an umbrella gun incident during the assassination of Bulgarian dissident Georgi Markov
the only other thing i could worry about is saturation of some hormonal mechanism, both ginseng and green tea are known to lower cortisol and potentially some overlap effect on the thyroid and adrenals too. Best thing is to listen to your body, run repeated experiments, and build on your knowledge with your own experience.
Edited by gamesguru, 23 June 2020 - 02:09 AM.