Here's an interesting article:
http://www.eurekaler...l-mnm020404.php
So is there a possibility that we can all benefit from this special IGF-1? Comments?
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Mice Regenerate Muscle Tissue
Started by
manofsan
, Jun 14 2005 05:58 AM
5 replies to this topic
#2
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Posted 14 June 2005 - 11:13 AM
I believe so! This produces a different result from hGH administration. If you recall discussions about it (mIGF1) were publsished in 2003 on the President's Council of Bioethics website. Only problem is the mode of delivery which at this stage appears to have only been done using direct gene to muscle type of administration so may not be quite ready for widespread usage (would not necessarily stop very determined athletes with very lateral minded physicians). 
#3
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Posted 14 June 2005 - 11:41 AM
I agree with you Prometheus. If determined athletes and sports doctors move into using mIGF-1 to summon stem cells for regenerative assistance, then it will usher in regenerative stem cell technology into the arena of competitive sports. Where there's demand, there'll be supply.
But then does mIGF-1 not achieve any of the conventional growth in muscle and connective tissue that HGH and IGF-1 give? Is it purely a stem cell summoner? Is it achieving similar results by different means?
What does the "m" in "mIGF-1" stand for, anyway? "modified"? "muscular"?
But then does mIGF-1 not achieve any of the conventional growth in muscle and connective tissue that HGH and IGF-1 give? Is it purely a stem cell summoner? Is it achieving similar results by different means?
What does the "m" in "mIGF-1" stand for, anyway? "modified"? "muscular"?
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#5
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Posted 15 June 2005 - 09:00 AM
The normal IGF-1 is mostly a hormone, i.e. it's made in the liver and goes to circulation. Other forms of IGF-1 such as muscle ("m") or brain one are local mediators, i.e. influence only the immediate surroundings of the cells that make them. I suspect this relates to the fact that mIGF-1 is not directly supplementable.
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