5 replies to this topic

[Michael-bret Hodges]

Hello community,

I'm new here, so let me introduce myself. I am 21 and a information systems major at Georgia State University. I recently went to the doctor after my roommate was worried I might have sleep apnea because of my snoring patterns and general lack of restful sleep. I have also been on b-12 500 mcg to increase my overall level of energy. It came to somewhat of a suprise to me after to me that my blood work came back with low levels of B-12.

My primary concern is the level of nerve damage that I might have suffered. Does anyone have any advise as how to correct this? Maybe a nootropic or lionmane?

[Hebbeh]

Normally if you are B12 deficient (and aren't vegan), you have pernicious anemia which is a lack of intrinsic factor. Intrinsic factor is a substance produced in the digestive tract that is required for the absorption and uptake of B12. If, in fact, you suffer from pernicious anemia, you will require B12 injections. Sometimes you can get by with megadosing B12 supplements as some with pernicious anemia still make intrinsic factor but just not in sufficient amounts. My mom has suffered with pernicious anemia most of her life and requires periodic B12 injections.

There is no replacement for B12 other than doing what it takes to get levels up to normal. In your case, it would be worthwhile to shoot for therapeutic levels for some period of time as the body plays catch up.

I should add that you should be supplementing with the active form of B12 (methyl B12 or methylcobalamin) rather than plain cyanocobalamin as you may also have a genetic polymorphism that inhibits the pathway to methylate the inactive form (cyanocobalamin) to the needed active form (methylcobalamin). Buy and try some methyl B12 (methycobalamin) which is dosed sublingually and bypasses the intrinsic factor required in oral dosing.

Edited by Hebbeh, 23 December 2013 - 09:17 PM.

[Hebbeh]

After you get your B12 levels stabilized with methyl B12, review these threads to encourage re-myelination with UMP, CDP-choline, phosphatidylcholine, fish oil (DHA), and co-factors. In regards to folate, I would also suggest the active methyl form (5-methylfolate ).

http://www.longecity...ne-uridine-dha/

http://www.longecity...ncrease-myelin/

[finalgates]

use high dosage methyl b12.i use 10mg now foods sublingual.and dibencozide source naturals 8,6mg.in beggining i had headachel more likely from healing.now i am only better.

[kurdishfella]

B12 also needs other b vitamins to work effectivelly b9, b5,and b2. check for other defiencies as well usually when you have one defiency you have more.

Edited by kurdishfella, 29 September 2021 - 08:54 AM.

[kurdishfella]

You probably had fake b12 supplement. In order for b12 to be fully active it needs to bind to a protein. takes about 3 weeks to correct defiency