10 replies to this topic

[jsncts]

Hey guys,

 

I've recently become interested in the study of longevity and human optmization, and I'd like to put together a relatively simple supplement stack to help get the most from my body and keep my health and cognitive function in tip top condition. I've included my weight lifting supplements in the list, though they are not really relevant.

 

I'm currently taking the following:

 

Morning:

1 x 10mg Lexapro (considering swapping SSRI for CDP Choline - see below)

1 x Swisse Mens Multi-Vitamin

1 x Triple Strength Fish Oil Cap

1 x Vitamin D3 1000iu (I get limited sunlight exposure at work)

30g Whey Protein
5g Creatine Monohydrate

 

Midday:
30g Whey Protein
7g BCAAs
14g Preworkout (Caffeine, Beta Alanine)

 

Evening:

1 x Ciplactin 1mg (Cyproheptadine Hydrochloride)

1 x Sublingual Melatonin 2.5mg

 

Just purchased:
800mg Piracetam tabs
300mg Alpha-GPC tabs

 

 

So, I'm looking to add to this list. Any suggestions?

Also, how should I proceed with the Piracetam and Alpha GPC? (dosage, etc)

Recently I've read alot about people replacing SSRI's with low dose CDP Choline. What do you guys think about this?

Edited by jsncts, 11 June 2014 - 04:17 AM.

[serp777]

I'd take out the sketchy SSRIs if possible. None of them seem to have nice long term side effects. Have you tried typtophan for depression? That is markedly safer and healthier than an SSRI.

 

It would probably be a good idea to add a magnesium supplement in there, since most Americans do not get enough from their diet.

 

Also if you're looking for more, check out ALCAR and alpha lipoic acid. Personally, also, i'd go with noopept if I was going to take a racetam.

[Dolph]

Suggesting a serotonin-precursor like tryptophan as a "safe alternative" to an SSRI is very sketchy. There is no reliably longterm safety data whatsoever (and NO hint of effectiveness either...) and given the problems with drugs that cause a systemic increase of serotonin I wouldn't be surprised at all if pulmonary hypertension and heart valve issues would be prominent in long term tryptophan users.

[serp777]

Suggesting a serotonin-precursor like tryptophan as a "safe alternative" to an SSRI is very sketchy. There is no reliably longterm safety data whatsoever (and NO hint of effectiveness either...) and given the problems with drugs that cause a systemic increase of serotonin I wouldn't be surprised at all if pulmonary hypertension and heart valve issues would be prominent in long term tryptophan users.

 

Many substances and supplements on this web site have little long term saftey data, including the variety of SSRIs. Tryptophan is an essential amino acid and gains some credibility in that sense. Pre and post workout powders can include trytophan as well. Notice how i did not specify the dosage. I was just wondering if the person had tried trytophan as an alternative, since logically it will probably have fewer long term side effects compared to SSRIs.

 

At least trytophan does have some long term studies, even though depression is not conclusive-

 

"Over the past 20 yr, 40 controlled studies have been described concerning the effects of L-tryptophan on human sleepiness and/or sleep. The weight of evidence indicates that L-tryptophan in doses of 1 g or more produces an increase in rated subjective sleepiness and a decrease in sleep latency (time to sleep)."

http://www.ncbi.nlm..../pubmed/6764927

[blood]

1 x Swisse Mens Multi-Vitamin

We know that people who use copper-containing multi-vitamins are at higher risk for dementia.

We also know that relatively small amounts of manganese delivered in highly bioavailable forms (for example when dissolved in drinking water) pose a threat to normal human cognitive function.

Swisse multivitamins contain these two potentially neurotoxic minerals. The forms of these minerals (copper & manganese) provided in the Swisse multi formulas are highly bioavailable and arguably dangerous when consumed over a long period.

E.g., this formulation [Swisse multi for older men] can only be described as evil - it provides multi mg doses of iron (undesirable for men without a deficiency), copper, & manganese:
http://www.swisse.co...ens-ultivite-f1

Edited by blood, 13 June 2014 - 05:22 AM.

[shifter]

Vitamin K2 and D3 are the only ones I would supplement with. The rest you can get more than adequate amounts in your diet. Or if you must supplement, supplement on real sources like chlorella and spirulina. A little bit of kelp if you don't have problems with iodine.

Multis use synthetic vitamins which are not as bio available such as Folic acid instead of Folate. Or way too much of a synthetic vitamin E.

If you want to boost your vitamin C, get a supplement derived from a real food like camu camu or amla. Might not be as much vitamin C per capsule but better for you

Ascorbic acid for vitamin C could be derived from GMO corn.

In short, take only what you need, and get the rest from real biological foods.

[Bluecheer]

1 x Swisse Mens Multi-Vitamin

We know that people who use copper-containing multi-vitamins are at higher risk for dementia.

We also know that relatively small amounts of manganese delivered in highly bioavailable forms (for example when dissolved in drinking water) pose a threat to normal human cognitive function.

Swisse multivitamins contain these two potentially neurotoxic minerals. The forms of these minerals (copper & manganese) provided in the Swisse multi formulas are highly bioavailable and arguably dangerous when consumed over a long period.

E.g., this formulation [Swisse multi for older men] can only be described as evil - it provides multi mg doses of iron (undesirable for men without a deficiency), copper, & manganese:
http://www.swisse.co...ens-ultivite-f1

Would something such as this be the case in most multi vitamins ? Or more specifically "centrums men's multi vitamin"?


Also jsncts I've very interested in your nootropic regimine and was wondering how your going with it ? Do you feel any more able to learn or increased memory and focus?

[yates9]

 

1 x Swisse Mens Multi-Vitamin

We know that people who use copper-containing multi-vitamins are at higher risk for dementia.

We also know that relatively small amounts of manganese delivered in highly bioavailable forms (for example when dissolved in drinking water) pose a threat to normal human cognitive function.

 

Hi, can you give a reference for this issue with copper and manganese?

 

I had searched the forums some years ago and settled on AOR Orthocore as being a reasonably balanced recommended multivitamin. Especially if taken much lower than recommended dose, argument might be if it has any effect at all.. But I read they have both copper 1.5mg and manganese 2.3 mg.

[jsncts]

Also jsncts I've very interested in your nootropic regimine and was wondering how your going with it ? Do you feel any more able to learn or increased memory and focus?

 

 

Honestly I didn't notice a great deal of difference on Piractem and Alpha GPC. I've tapered off until I can kick the SSRI (Lexapro) as I feel it has too many unpleasant interactions with other compounds. Once the SSRI is completely clear of my system (I will be tapering to avoid withdrawals/sides) I plan on experimenting with Noopept and Piracetam and seeing which, if either, works best for me. A friend of mine just started a Noopept regime and says he notices a big difference.

[Bluecheer]

 

Also jsncts I've very interested in your nootropic regimine and was wondering how your going with it ? Do you feel any more able to learn or increased memory and focus?

 

 

Honestly I didn't notice a great deal of difference on Piractem and Alpha GPC. I've tapered off until I can kick the SSRI (Lexapro) as I feel it has too many unpleasant interactions with other compounds. Once the SSRI is completely clear of my system (I will be tapering to avoid withdrawals/sides) I plan on experimenting with Noopept and Piracetam and seeing which, if either, works best for me. A friend of mine just started a Noopept regime and says he notices a big difference.

 

I was going to try the Noopept and Pircatem combo but Ive been a little worried about noopept as i remember hearing it is quite bad for you in the long run, but im not sure how legit that reference was. You should update on how you feel when you try it.

Im thinking of trying phenylpiractem + noopept or just phenylpiractem

[jsncts]

I've read only positive things about Noopept, but will be doing a lot more research before taking it. Will definitely report back with my experiences. Good luck!