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A summary of the state of research with Nicotinamide Riboside

nicotinamide riboside guarante sinclair

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#1 maxwatt

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Posted 12 March 2015 - 07:04 PM




A summary of the state of research with Nicotinamide Riboside appears in the above blog by David Stipp on Scientific American's website.  It somewhat predictably concludes :


 If I were a middle-aged mouse, I’d be ready to spend some of the nickels and dimes I’d dragged off the sidewalk to try NR supplements. Even before Sinclair’s paper, researchers had shown in 2012 that when given doses of NR, mice on high-fat diets gained 60 percent less weight than they did on the same diets without NR. Further, none of the mice on NR showed signs of diabetes, and their energy levels improved. The scientists reportedly characterized NR’s effects on metabolism as “nothing short of astonishing.”

But the paucity of human data gives me pause.

Still, there is a basic summary of what is known and how we know it.


David Stipp is a Boston science writer who has focused on gerontology since the late 1990s. His book on the subject, The Youth Pill: Scientists at the Brink of an Anti-Aging Revolution, was published in 2010, and his article, “A New Path to Longevity," appears in the January 2012 issue of Scientific American. Stipp blogs about aging science here.


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