DMAE is particularly attractive as a cholinergic drug due to its affordability and enduring nootropic status. The pharmacodynamics of DMAE are still somewhat unknown. It appears to provide a multitude of benefits relevant to anti-ageing medicine.
DMAE is partially converted to choline via cellular phospholipid metabolism: http://www.ncbi.nlm..../pubmed/1173033
Administration of DMAE did not influence brain Acetylcholine levels in rodents: https://www.ncbi.nlm...v/pubmed/850128
DMAE as a scavanger of free radicals:
http://www.ncbi.nlm..../pubmed/6099712
http://www.ingentaco...000001/art00008
DMAE is converted to phosphatidyl-DMAE, which acts as an antioxidant and is incorporated into cell-walls: https://www.ncbi.nlm.../pubmed/2517957
DMAE displays anti-inflamatory properties: https://www.ncbi.nlm...pubmed/15675889
Administration of DMAE in rodents produced a reduction of lipofuscin pigment in the cortex and hippocampus: http://www.readcube.....1978.tb02544.x
This article makes a lot of claims, including increased brain glucose consumption and anti-hypoxia effects, but the references cited are paywalled: http://smart-drugs.n...le-lucidril.htm
Anyone have some new insights to DMAE that I may have missed? What do you guys think about using DMAE with uridine, rather than the more common alpha-GPC? It seems to be effective for increasing available phospholipids and choline.
