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Results of my 1.5 years of injecting exogenous GDF11

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#241 echoman

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Posted 01 April 2018 - 10:42 PM

Hello folks.... I'm reading where Steve's latest dosing regime is 100 pg/week...diluted bacteriostatic water mix is at 1 unit = 5 pg of GDF11. I'm a little stumped on this one. What's the best way to do this? I can only seem to find Bacteriostatic  water in 30ml bottles. 



#242 stevegperry

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Posted 03 April 2018 - 01:31 AM

Echoman,

 

Yes, diluting something down to where a unit equals only a few picograms is tricky and requires at least two 30 ml bottles of bacteriostatic water.  Here are some formulas and examples to help you out: https://drive.google...d8NTrW61lcf9EVg

 



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#243 echoman

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Posted 04 April 2018 - 12:14 AM

Thankyou very much Steve !



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#244 onz

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Posted 27 April 2018 - 04:52 PM

Steve is scheduled to be one of our guests on the next Longecity podcast!

 

If you have any questions you would like us to ask him post them in this thread: https://www.longecit...th-steve-perry/


Edited by onz, 27 April 2018 - 04:53 PM.


#245 theobromananda

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Posted 09 February 2019 - 04:47 PM

I am interested in ultra-low dosing this as a 20-something. If a 40 year old has 1400ng circulating GDF11, a newborn should have 3500ng considering a decrease of1%/year. Instead of doing the latest low dose of 250 picograms/day for 4-6 weeks, I'd maybe doing a load phase of 40 picograms for 2 weeks at most, and then a dose of 10 pg every one or two weeks.

 

I'd be monitoring the vitals of course, but as my reaction time or blood pressure or HRV probably have not degenerated too much, I would not know what to look for. I am not looking to increase any vitality, I am looking to conserve my health before it deteriorates.

 

Any ideas?



#246 stevegperry

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Posted 09 February 2019 - 07:12 PM

Theo,

 

Read GDF11Rejuvenation.com thoroughly, especially the paper.  I've given up on any kind of formula for GDF11 dosing.  The amount you need to down regulate for my 50+ crowd is typically between 10,0000 and 20,000 pg.  People who exercise need less, sedentary people more. 

 

I have very little data on 20 and 30 somethings, but I'd take no more than 50 pg/day and then watch trending like a hawk.  You could easily down regulate at 2000 pg or less.


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#247 Puppalupacus

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Posted 09 February 2019 - 07:39 PM

So how would you inject endogenous GDF-11?



#248 stevegperry

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Posted 09 February 2019 - 08:16 PM

Please read GDF11Rejuvenation.com on how to inject GDF11.  it's a tough cytokine to work with since you need to titrate dose to key biomarkers like BP, pulse, HRV and reaction time.  That's why most people who take GDF11 join our study.


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#249 ortcloud

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Posted 08 August 2019 - 03:50 PM

Thankyou very much Steve !

 

@echoman

 

It looks like it has been a couple of years since you started.

 

Can you give us an update on your gfd11 experience ?



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#250 ortcloud

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Posted 11 October 2019 - 07:56 PM

Theo,

 

The amount you need to down regulate for my 50+ crowd is typically between 10,0000 and 20,000 pg. 

 

Steve

Am I reading this right? You are saying the starting dose is 10,000pg per day?

 

You recently said 250pg per day is the starting dose for 4-6 weeks.

 

Perhaps you mean total dose 250pg per day times 42 days is 12,500

 

thanks



#251 nickthird

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Posted 16 October 2019 - 03:03 PM

The most important question of the millenium..... You who took this, did it help expand your vocal range or rejuvenate it to a higher pitch?


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#252 lost69

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Posted Today, 12:43 AM

The most important question of the millenium..... You who took this, did it help expand your vocal range or rejuvenate it to a higher pitch?

 

i posted already about this, i got back my whistle register at about 48yo (now 50) and it slowly consolidated like i had it in the past (i think i lost it at about 40yo).it did not expand, just gave me back my range like when i was younger

 

the range goes up til about c7 (vitas dedication).it also boosted all other registers to allow me to sing metal songs like steel heart, queensryche and michael kiske like nothing...i mean vocal folds so elastic like a teen that i can sing low volume, high volume, very little air support or even lack of air support by mistake and the notes come out well anyway

 

the only bad thing is i developped faryngeal reflux lately, at first i could sing despite throat ache but now some days i cannot keep vocal folds closed and i get craks and so on at those very high notes, so some days i cannot sing at all but on no reflux days the range is all there

 

another example: rob halford had lost is range, quite normal at 68yo and this year he has recovered so much range, he probably used stuff like this


Edited by lost69, Today, 12:46 AM.


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#253 nickthird

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Posted Today, 04:09 AM

What is the starting dose for someone close to age 30?

 

Also, does it matter if the source of GDF-11 is E. Coli?


Edited by nickthird, Today, 04:53 AM.






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