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Trehalose as a cryoprotectant

cryoprotectant trehalose

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3 replies to this topic

#1 Astrocyte

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Posted 05 March 2016 - 05:46 PM


Any tought on using trehalose as a cryoprotectant?

 

Why not use this thread to consolidate information on the subject.

 

 

 



#2 Danail Bulgaria

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Posted 06 March 2016 - 10:50 AM

This is old information. Trechalose has cryoprotective properties. It is not used for people. I don't know why. 



#3 Astrocyte

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Posted 07 March 2016 - 10:22 AM

This is old information. Trechalose has cryoprotective properties. It is not used for people. I don't know why. 

 

This is why I started this thread. Trehalose is available economically since 2000. It is a molecule similar to sucrose and seem not being a problem in regard of biocompatibility. Insects and micro-animals use it as a cryptobiotic agent.

 

The intend was if anybody is aware of its experimental use as a cryoprotectant.
 



#4 Polyamine

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Posted 07 March 2016 - 11:21 AM

It could be that Trehalose just helps balance glutamate by stabilizing S-adenosyl-l-methionine.  Shiitake mushrooms are a soucre of Trehalose.

 

http://www.ncbi.nlm....les/PMC2708026/

 

http://www.sciencedi...304416502003331







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