This is about cycloastragenol's effects independent of telomerase and telomeres.
I tried 5mg of cycloastragenol with a meal for the first time yesterday.
My experience, but I may revise this, is that it has anti-glutamine/glutamate properties. Some have noted that it has given them "caffeine withdrawal" headaches which would make sense out of this.
It does produce anxiety and a weird "inner tension" sort of adrenaline feeling, comparable to being at a great height and having a strong fear of heights.
Maybe it has affinity for adrenergic receptors?
Some say that it is energizing and improves their sleep and lowers their sleep requirement but this wasn't my experience. I did also take melatonin so it's possible that it interfered.
What is its half-life? I absolutely can't find a single thing about this anywhere, neither on the TA-65 nor Wikipedia page, or anywhere else.