But, what is that? Meta-analyses? Epidemiology? What is it?
And from whom? The English seems a bit broken.
And whom were the people used for the trials? Did they have a history of CAD, did it run strongly in their families? What was their overall lifestyle like?
These are pertinent questions.
Your are funny. I'm not a native english speaker and the abstract is very clear on all your questions
What is it? - A meta analysis of primary prevention and secondary prevention randomized controled trials, as outlined below:
METHODS:
We undertook meta-analyses of serious vascular events (myocardial infarction, stroke, or vascular death) and major bleeds in six primary prevention trials (95,000 individuals at low average risk, 660,000 person-years, 3554 serious vascular events) and 16 secondary prevention trials (17,000 individuals at high average risk, 43,000 person-years, 3306 serious vascular events) that compared long-term aspirin versus control. We report intention-to-treat analyses of first events during the scheduled treatment period.
By whom? - they even mention a email address:
Antithrombotic Trialists' (ATT) Collaboration1,
Baigent C,
Blackwell L,
Collins R,
Emberson J,
Godwin J,
Peto R,
Buring J,
Hennekens C,
Kearney P,
Meade T,
Patrono C,
Roncaglioni MC,
Zanchetti A.
Collaborators (39)
Collins R, Peto R, Hennekens C, Doll R, Bubes V, Buring J, Dushkesas R, Gaziano M, Hennekens C, Brennan P, Meade T, Rudnicka A, Hansson L, Warnold I, Zanchetti A, Avanzini F, Roncaglioni MC, Tognoni G, Buring J, Chown M, Gaziano M, Hennekens C, Baigent C, Barton I, Baxter A, Bhala N, Blackwell L, Boreham J, Bowman L, Buck G, Collins R, Emberson J, Godwin J, Halls H, Holland L, Kearney P, Peto R, Reith C, Wilson K.
And whom were the people used for the trials? - also already found in Methods part of the abstract quoted above
(95,000 individuals at low average risk, 660,000 person-years, 3554 serious vascular events)
(17,000 individuals at high average risk, 43,000 person-years, 3306 serious vascular events)
With more than 112,000 in total studied individuals, probably representative of the general population.
Its scary, if one isn't able to read such a simple abstract.